Effect of anxiety on propofol induced decrease in blood pressure in children undergoing elective surgery

Not yet recruiting

• Conditions: Children undergoing elective surgery under general anaesthesia induced with propofol

• Registration Number: CTRI/2017/11/010649
• Lead Sponsor: AIIMS New Delhi

Brief Summary

1.     DREGER VA,TREMBECK TF: Management of perioperative anxiety in children. AORN Journal;2006,84(5):788-804.

2.     Fortier MA, Del Rosario AM, Martin SR,Kain ZN. Perioperative anxiety in children. Paediatr Anaesth. 2010;20:318-322.

3.      Kain ZN, Wang SM, Mayes LC, Caramico LA,Hofstadter MB. Distress during the induction of anesthesia and postoperative behaviouraloutcomes. Anesth Analg. 1999;88:1042-1047.

4.     Kain ZN, Mayes LC, Caldwell-Andrews AA,Karas DE, McClain BC. Preoperative anxiety, postoperative pain, and behavioralrecovery in young children undergoing surgery. Pediatrics. 2006;118:651-658.

5.     Reves JG, Glass P, Lubarsky DA.Miller’s Anesthesia. 7 Churchill Livingstone; Philadelphia:2010. IntravenousAnaesthetics.

6.     RothW, Dobrenz S, Dietal A, et al. Sympathetic activation in broadly definedgeneralized activation anxiety disorder. J Psychiatr Res. 2008;42:205-12.

7.     HanssR, Bein B, Ledowski T, et al. Heart rate variability predicts severehypotension after spinal anesthesia foe elective caesarean delivery.Anesthesiology.2005;102:1086-93.

8.     Morley AP,Papageorgiou CH, Marinaki AM, Cooper DJ and Lewis CM. The effect ofpre-operative anxiety on induction of anaesthesia with propofol. Anaesthesia2008; 63(5):467-473.

9.     Kain ZN, Mayes LC, Cicchetti DV,Bagnall AL, Finley JD, Hofstadter MB. The Yale Preoperative Anxiety Scale: howdoes it compare with a “gold standardâ€? Anesth Analg. 1997;85:783-788.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2017-11-25
• Study Start: 2018-01-01

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

The study will be conducted on 100 children in age group of 3-12 years, ASA grade I and II, undergoing elective day care surgeries.

Exclusion Criteria

Emergency surgery, child with developmental delay, age <3 years and >12years.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To assess the prevalence of preoperative anxiety in children of Indian population prior to surgery.	Every minute after anaesthesia induction with propofol till 10th minute
propofol.	Every minute after anaesthesia induction with propofol till 10th minute
To assess the effect of preoperative anxiety on arterial pressure changes after induction with	Every minute after anaesthesia induction with propofol till 10th minute

Secondary Outcome Measures

Name	Time	Method
No secondary outcomes are studied	Not applicable

Trial Locations

Locations (1)

AIIMS New Delhi; 🇮🇳 South, DELHI, India

AIIMS New Delhi

🇮🇳South, DELHI, India

Dr Puneet Khanna

Principal investigator

9873106516

k.punit@yahoo.com