Continuous Versus 1-min Oscillometric Arterial BP Monitoring
- Conditions
- Anesthesia, General
- Interventions
- Device: 1-min interval oscillometric methodDevice: arterial catheterization method
- Registration Number
- NCT05792436
- Lead Sponsor
- Seoul National University Hospital
- Brief Summary
Hypotension is common during surgery and about one-third of hypotension occur during the period from anesthesia induction to skin incision. Therefore, monitoring blood pressure during this period is crucial.
Two methods are used for measuring blood pressure during surgery: the intermittent measurement method (oscillometric method) and the continuous measurement method (arterial catheterization method). The latter is frequently used in surgical patients who require meticulous hemodynamic management, although there is no clearly defined indication for its use. Despite the benefits of arterial catheterization, it is often delayed after induction of general anesthesia, and blood pressure is monitored intermittently using the oscillometric method.
A recent study showed that continuous arterial pressure monitoring using arterial catheterization method during the induction of general anesthesia reduced hypotension significantly compared to 2.5-min interval intermittent arterial pressure monitoring using oscillometric method. The study was conducted on patients scheduled for continuous arterial pressure monitoring during surgery and the group with continuous arterial pressure monitoring showed significantly lower incidence of hypotension during the first 15 minutes of anesthesia induction.
However, measuring blood pressure using the oscillometric method at 1-min interval, rather than 2.5-min interval, may not be significantly inferior to continuous monitoring via arterial catheterization in terms of hypotension occurrence. This study aims to compare hypotension incidence between arterial catheterization method and oscillometric method with 1-min interval during induction of anesthesia in non-cardiac surgery patients.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 244
- Adult patients aged 19 or older undergoing scheduled non-cardiac surgery with general anesthesia and continuous invasive arterial blood pressure monitoring via the radial artery
- Arterial access is clinically necessary before induction of anesthesia (e.g., moderate or higher degree of aortic stenosis, moderate or higher degree of heart failure, coronary artery disease requiring revascularization, intracranial aneurysm with a significant risk of rupture, etc.)
- Emergency surgery
- American Society of Anesthesiologists (ASA) physical status 5 or 6
- Arterial access is required in a different artery other than the radial artery (e.g., the femoral artery)
- Electrocardiogram other than sinus rhythm
- Refusal to participate in the study
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description 1-min interval oscillometric method 1-min interval oscillometric method 1-min interval blood pressure monitoring using oscillometric method during induction of anesthesia arterial catheterization method arterial catheterization method Continuous blood pressure monitoring through arterial catheter during induction of anesthesia
- Primary Outcome Measures
Name Time Method MAP integral From the start of anesthesia induction to 15 minutes after The area under the mean arterial pressure (MAP) of 65 mmHg calculated using the MAP recorded every second
- Secondary Outcome Measures
Name Time Method Area under MAP of 60, 50, 40 mmHg (mmHg∙min) From the start of anesthesia induction to 15 minutes after calculated using the MAP recorded every second
Exposure to MAP <65, <60, <50, and <40 mmHg (binary) From the start of anesthesia induction to 15 minutes after calculated using the MAP recorded every second
MAP standard deviation (mmHg) From the start of anesthesia induction to 15 minutes after calculated using the MAP recorded every second
Use of vasopressor (dose) From the start of anesthesia induction to 15 minutes after ephedrine (mg), phenylephrine (μg/kg), norepinephrine (μg/kg)
Duration of MAP <65, <60, <50, <40 mmHg (min) From the start of anesthesia induction to 15 minutes after calculated using the MAP recorded every second
Exposure to continuous MAP <65, <60, <50, <40 mmHg for 1 minute or longer (binary) From the start of anesthesia induction to 15 minutes after calculated using the MAP recorded every second
Area above MBP of 100, 110, 120, 140 mmHg (mmHg∙min) From the start of anesthesia induction to 15 minutes after calculated using the MAP recorded every second
Crystalloid (ml) From the start of anesthesia induction to 15 minutes after Total amount of crystalloid administered
Use of vasopressor (binary) From the start of anesthesia induction to 15 minutes after ephedrine, phenylephrine, norepinephrine (binary)
Trial Locations
- Locations (2)
Seoul National University Hospital
🇰🇷Seoul, Korea, Republic of
Korea University Guro Hospital
🇰🇷Seoul, Korea, Republic of