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Clinical Trials/NCT04662645
NCT04662645
Completed
Not Applicable

Embedded Palliative Care in the Management of Advanced Thoracic Malignancies

Ohio State University Comprehensive Cancer Center1 site in 1 country68 target enrollmentDecember 12, 2018

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Caregiver
Sponsor
Ohio State University Comprehensive Cancer Center
Enrollment
68
Locations
1
Primary Endpoint
Capacity and productivity to be evaluated
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

This trial studies how well embedded palliative care works in managing symptoms in participants with stage III-IV thoracic malignancies that has come back and their caregivers. Embedded palliative care may improve distress and anxiety in participants and caregivers.

Detailed Description

PRIMARY OBJECTIVES: I. To determine feasibility of embedding a palliative care (PC) physician within the James Thoracic Oncology Clinic. II. To assess patient and caregiver outcomes over a 12-month period within an embedded onco-palliative care clinic model. III. To evaluate and describe clinician attitudes and beliefs regarding utilization of embedded palliative care as well as symptoms of provider burnout. IV. To analyze health care utilization among participants receiving embedded onco-palliative care. OUTLINE: Participants and caregivers undergo embedded palliative care comprising symptom management (physical and psychological), advanced directives and goals of care discussion, caregiver support, and referral for adjunctive supportive services as needed at each clinic visit. After completion of study, patients are followed for up to 1 year.

Registry
clinicaltrials.gov
Start Date
December 12, 2018
End Date
December 5, 2020
Last Updated
2 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Carolyn Presley

Principal Investigator

Ohio State University Comprehensive Cancer Center

Eligibility Criteria

Inclusion Criteria

  • Patients with advanced or metastatic cancer of the chest (lung, thymus, or pleura): stage III or IV, recurrent disease
  • Patients will receive therapy (chemotherapy, immunotherapy, targeted therapy or radiation therapy) at The Ohio State University
  • New patients (defined as patients who have received no therapy for metastatic disease or have started treatment for metastatic disease within the last 30 days) or established patients with advanced cancer receiving anti-cancer therapy, no limit on prior therapies
  • Patient and caregiver must be able to read and understand consent form
  • Patients must designate a willing caregiver to participate although caregiver consent is not required for patient participation

Exclusion Criteria

  • Patients who are already enrolled or have been previously enrolled in palliative care or hospice services as an outpatient. Inpatient palliative care consultation prior to enrollment is permitted
  • Patients who do not qualify for active anti-cancer therapy and opt to enroll in hospice services prior to study enrollment
  • Patients who are unable to read or understand consent form
  • Patients receiving primary systemic treatment outside of Ohio State. Outside radiation therapy is permitted

Outcomes

Primary Outcomes

Capacity and productivity to be evaluated

Time Frame: Up to 12 months

Clinician capacity and productivity will be evaluated by looking at scheduling as well as billing productivity. Preliminary data will be summarized and collected. Confidence intervals will also be calculated for feasibility rates.

Anxiety assessment using Hospital Anxiety and Depression Scale (patient outcome)

Time Frame: Up to 12 months

Anxiety assessed using the Hospital Anxiety and Depression Scale

Work/social needs assessed using SCNS- P and C (Caregiver outcome)

Time Frame: Up to 12 months

Caregiver needs assessment using Supportive Care Needs Survey - Patients \& Caregivers (SCNC-P\&C)

Information needs assessed using SCNS- P and C (Caregiver outcome)

Time Frame: Up to 12 months

Caregiver needs assessment using Supportive Care Needs Survey - Patients \& Caregivers (SCNC-P\&C)

Demand of palliative care services to be evaluated

Time Frame: Up to 12 months

Preliminary data will be summarized and collected. Confidence intervals will also be calculated for feasibility rates.

Symptom burden (patient outcome) supportive care screen

Time Frame: Up to 12 months

Will be assessed using Supportive care screen.

Symptom burden (patient outcome) Functional Assessment of Cancer Therapy-Lung

Time Frame: Up to 12 months

Will be assessed using Functional Assessment of Cancer Therapy-Lung

Symptom burden (patient outcome) using HADS

Time Frame: Up to 12 months

Will be assessed using Hospital Anxiety and Depression Scale (HADS)

Functional status assessed using Functional Activities Scale (patient outcome)

Time Frame: Up to 12 months

Functional status assessment using Functional Activities Scale (FAS)

Psychological/emotional needs assessed using SCNS- P and C (Caregiver outcome)

Time Frame: Up to 12 months

Caregiver needs assessment using Supportive Care Needs Survey - Patients \& Caregivers (SCNC-P\&C)

Acceptance from providers to assess utilization of palliative care services

Time Frame: Up to 12 months

Acceptance will be evaluated utilizing provider surveys (to capture provider opinions on palliative care utilization) as well as rate of enrollment. Preliminary data will be summarized and collected. Confidence intervals will also be calculated for feasibility rates.

Resource assessment of staff and space

Time Frame: Up to 12 months

Resources required, including patient care rooms and nursing support will also be evaluated. Preliminary data will be summarized and collected. Confidence intervals will also be calculated for feasibility rates.

Symptom burden using National Comprehensive Cancer Network distress thermometer (patient outcome)

Time Frame: Up to 12 months

Will be assessed using National Comprehensive Cancer Network distress thermometer

Depression assessment using Hospital Anxiety and Depression Scale (patient outcome)

Time Frame: Up to 12 months

Depression assessed using the Hospital Anxiety and Depression Scale

Health care service needs assessed using Supportive Care Needs Survey Partners and Caregivers (SCNS- P and C) (Caregiver outcome)

Time Frame: Up to 12 months

Caregiver needs assessment using Supportive Care Needs Survey - Patients \& Caregivers (SCNC-P\&C)

Health care utilization outcomes

Time Frame: Up to 12 months

Will be captured using Integrated Health Information Systems electronic medical record data as well as patient reported events.

Self-reported barriers and attitudes regarding palliative care assessed using Ohio State Palliative Care Provider Survey (Provider outcome)

Time Frame: Up to 12 months

Ohio State Palliative Care Provider survey used to assess perceived barriers to referral

Secondary Outcomes

  • Challenges for patients, caregivers, and the treating oncologist in an embedded palliative care model(Up to 12 months)

Study Sites (1)

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