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Indirect Measurement of Respiratory Quotient in Unipulmonary Ventilation.

Completed
Conditions
Respiratory Quotient Measurement
Registration Number
NCT03751605
Lead Sponsor
Centre Hospitalier Universitaire, Amiens
Brief Summary

The measurement of VO2 and VCO2 makes it possible to calculate the respiratory quotient (RQ) (VCO2 / VO2) which is a reflection of human energy metabolism and therefore of anaerobiosis. A study has been conducted in our department to demonstrate the ability of the indirectly measured respiratory quotient (RQ) from the inspired and exhaled breath analysis of the anesthetic respirator to predict the onset of anaerobic metabolism and postoperative complications in the operating room.

Unipulmonary ventilation is the rule in thoracic surgery: it improves surgical exposure and protects the operated lung.

However, no study has examined the impact of these mechanisms on the indirect measurement of RQ in unipulmonary ventilation. The main objective of our work is to validate indirect RQ measurement during unipulmonary ventilation. The secondary objective was to assess the predictability of postoperative complications of indirect QR.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
50
Inclusion Criteria
  • Age>18 years old
  • Adults admitted to the operating room for thoracic surgery requiring unipulmonary ventilation
Exclusion Criteria
  • Cardiac surgery
  • Laparoscopy
  • Preoperative oxygen therapy

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Indirect respiratory quotientduring surgery
Secondary Outcome Measures
NameTimeMethod
occurrence of at least one post-operative complicationthrough study completion, an average of 6 months

the aim is to predict the occurrence of at least one complication with the use of indirect respiratory quotient

Trial Locations

Locations (1)

CHU Amiens

🇫🇷

Amiens, France

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