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Effect of combined COX-1 and COX-2 inhibition on platelet aggregation in-vivo

Conditions
enhanced clotting
thrombosis
10034468
10014523
Registration Number
NL-OMON30233
Lead Sponsor
Vrije Universiteit Medisch Centrum
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
Not specified
Target Recruitment
20
Inclusion Criteria

healthy men

Exclusion Criteria

Use of medical drugs, smoking, supersensitivity to aspirin

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>Amount of aggregation to ADP and epinephrine before and after aspirin at some<br /><br>seconds after the blood left the canula</p><br>
Secondary Outcome Measures
NameTimeMethod
<p>Amount of aggregation to ADP and arachidonic acid before and after aspirin in a<br /><br>whole blood aggregopmeter , at more than one hour after blood collection</p><br>
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