Evaluating combined intraarticular and intraosseous PRP Vs intraarticular PRP injection in early knee osteoarthritis.
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 42
- 试验地点
- 1
- 主要终点
- Assessment of improvements in clinical VAS score, radiological parameters, and functional outcomes using WOMAC and KOOS scores
研究概览
简要总结
Patients presenting with symptoms of early osteoarthritis of knee in PGIMER OPD will be evaluated for the study after clinical and radiological examination. Those who are in the inclusion criteria will be recruited under one of the two groups which include combined intraarticular with intraosseous PRP and intraarticular PRP alone in randomized manner.
Clinical outcome will be evaluated by questionnaire follow up in 1st, 3rd and 6th month for each sample.
The aim of the study is to evaluate whether there is any significant difference in the clinical outcome between the two groups of patients
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Investigator Blinded
入排标准
- 年龄范围
- 35.00 Year(s) 至 70.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients from age of 35 to 70.
排除标准
- •Secondary osteoarthritis.
- •Immunocompromised status or uncontrolled diabetes.
- •Symptomatic OA affecting joints other than the knee.
- •Recent intra-articular steroid or hyaluronic acid injections in the knee joint.
- •Anticoagulation therapy.
- •Active or previous infections.
结局指标
主要结局
Assessment of improvements in clinical VAS score, radiological parameters, and functional outcomes using WOMAC and KOOS scores
时间窗: 6 months
次要结局
- To look for any adverse effects due to combined intra-osseous and intra-articular PRP injection in early OA knee (fever, pain, allergic reactions etc).(6 months)
研究者
Dr Ankit Dadra
Post graduate Institute of Medical Education and Research