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Effect of Chlorhexidine, Fluoride and Green Tea Oral Gel on Pediatric Salivary Cariogenic Bacteria

Phase 1
Completed
Conditions
salivary S. mutans and Lactobacillus in children
Child, Chlorhexidine, Fluoride, Green tea, Streptococcus mutans, Real-time PCR
Registration Number
TCTR20210913005
Lead Sponsor
Kerman University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
60
Inclusion Criteria

Children who were in good physical health with no systemic diseases who had not used antibiotics at least 3 weeks before the study, were included. Other inclusion criteria were the absence of oral soft tissue lesions, any active or severe periodontal disease and no prosthetic or orthodontic appliances. Also, it was confirmed that participants had no history of food or drug allergies and had not used xylitol gums or any type of mouthwash or gel containing fluoride at least 3 weeks before the study.

Exclusion Criteria

Children who were in good physical health with no systemic diseases who had not used antibiotics at least 3 weeks before the study, were included. Other inclusion criteria were the absence of oral soft tissue lesions, any active or severe periodontal disease and no prosthetic or orthodontic appliances. Also, it was confirmed that participants had no history of food or drug allergies and had not used xylitol gums or any type of mouthwash or gel containing fluoride at least 3 weeks before the study

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
salivary S. mutans and Lactobacillus before intervention, 30 minutes and one week after intervention Based on laboratory guidelines, samples were stored in a container with ice cubes and transferred to the laboratory for analysis with real-time quantitative Polymerase Chain Reaction).
Secondary Outcome Measures
NameTimeMethod
/A N/A N/A
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