Clinical study to evaluate the effectiveness of Physostigma venenosum 6c, Eserinum 6c and homoeopathic ‘constitutional remedies’ in developmental myopia
Trial Snapshot
- Phase
- Phase 4
- Status
- Recruiting
- Sponsor
- Enrollment
- 160
- Locations
- 1
- Primary Endpoint
- All three medicines were effective in slowing down myopia progression, also reduction in diopters is noted along with reduction in the intensity of the associated symptoms.​
Study Overview
Brief Summary
​The complications caused by myopia is more than the complications of eye conditions caused by diabetes.​Homoeopathy has registered success records in treating various ophthalmic conditions.​ Homoeopathy offers simple solutions as an alternative to the intricate daily routines, expensive and invasive procedures which are usually suggested to reduce the progression of myopia. The increasing problem of myopia can be tackled well with proper use of Homoeopathic medicines.​Previous studies has been conducted with Ruta grav., Physostigma vene., constitutional medicines from BBCR repertory. ​Current study aims to see the effectiveness of Phys ven. 6C, Eser. 6C and Constitutional remedy with a control group.
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Masking
- None
Eligibility Criteria
- Ages
- 19.00 Year(s) to 45.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •Participants with varying degrees of myopia more than​ -0.5D, with a specified age range 19 years to 45 years, will be included.​ Moderate to High myopic children in ages ranging 7 to 11 years.​ Moderate to low myopic children in ages ranging 7 to 11 with parental myopic history are included.​ Bilateral or unilateral myopia (ICD11-9D00.0) associated with astigmatism, blurred vision, headache or eye strain are included.​.
Exclusion Criteria
- •Anyone who is already under homoeopathic treatment.​ Anyone who has undergone recent myopia-related treatment (use of ophthalmic solutions or surgical measures).​ Congenital conditions (ICD11-LD27.Y, LA14.0Y, LA12.Y, 9B70)​ Degenerative myopia (ICD11-9B76)​.
Outcomes
Primary Outcomes
All three medicines were effective in slowing down myopia progression, also reduction in diopters is noted along with reduction in the intensity of the associated symptoms.​
Time Frame: Ophthalmic assessment done once in three months until one year and followed up for six more months
​
Time Frame: Ophthalmic assessment done once in three months until one year and followed up for six more months
Progression of myopia was better in the constitutional medicine group.​
Time Frame: Ophthalmic assessment done once in three months until one year and followed up for six more months
No remission of myopia or associated symptoms post treatment with constitutional medicine.​
Time Frame: Ophthalmic assessment done once in three months until one year and followed up for six more months
Secondary Outcomes
- Establishing anti myopic activity of specific drugs(Every three months after the beginning of treatment protocol ophthalmic assessment is done for one year, i.e., four assessments for each patient)
Investigators
Antony Rozario J
Vinayaka mission’s homoeopathic medical college and hospital, VMRF-DU, Salem