A Prospective Study of Acute Nontraumatic Chest Pain - Warning and Classification
概览
- 阶段
- 不适用
- 干预措施
- Clinical evaluation, laboratory and cardiac imaging results, medication, surgery, and any hospitalization
- 疾病 / 适应症
- Chest Pain
- 发起方
- Xiao-nan He
- 入组人数
- 10000
- 试验地点
- 1
- 主要终点
- Adverse events
- 状态
- 招募中
- 最后更新
- 2个月前
概览
简要总结
Acute non-traumatic chest pain is one of the common causes of presentation in emergency patients, but the causes of acute non-traumatic chest pain are complex, the severity of the condition varies greatly, and the specificity of symptoms is not high. Machine learning and intelligent auxiliary models can greatly shorten the time of clinical decision-making, and improve the accuracy of etiological diagnosis in patients with chest pain, reduce the rate of misdiagnosis and missed diagnosis, and provide a clear direction for further treatment.
详细描述
Prospective observational studies used outpatient and follow-up information to construct an auxiliary early warning model of acute non-traumatic chest pain based on federated learning, and optimized the accuracy of early warning models through retrospective and prospective studies of large cohort data, and established an efficient and stable early warning and classification model for acute non-traumatic chest pain.
研究者
Xiao-nan He
Chief physician of Emergency and Critical Care Center of Beijing Anzhen Hospital
Beijing Anzhen Hospital
入排标准
入选标准
- •Age ≥ 18 years
- •Symptom onset or worsening within 24 hours before presentation, with a chief complaint of acute chest pain meeting the broad definition of chest pain (2021 AHA)
- •Presentation to the emergency department, with a clinical diagnosis consistent with non-traumatic chest pain
- •Signed informed consent
排除标准
- •traumatic chest pain
- •systemic pain caused by malignant tumors or rheumatic diseases involving the chest
- •Patients were lost to follow-up
研究组 & 干预措施
No cardiovascular adverse and cerebrovascular events (MACCE) occurred during the 1-month period
No cardiovascular and cerebrovascular adverse events (MACCE)，which included cardiovascular death, all-cause mortality, nonfatal myocardial infarction, refractory angina, new onset heart failure and stroke. Follow-up visits are conducted by in-person or telephone and registration is carried out.
干预措施: Clinical evaluation, laboratory and cardiac imaging results, medication, surgery, and any hospitalization
Group of major cardiovascular and cerebrovascular adverse events (MACCE) occurring during 1 month
Cardiovascular and cerebrovascular adverse events occur, the rest of the same as in the previous group
干预措施: Clinical evaluation, laboratory and cardiac imaging results, medication, surgery, and any hospitalization
结局指标
主要结局
Adverse events
时间窗: 30 days after presenting to the emergency departments(ED)
The primary outcome was a composite of adjudicated major adverse cardiovascular and cerebrovascular events (MACCE), which included cardiovascular death, all-cause mortality, nonfatal myocardial infarction, refractory angina, new onset heart failure and stroke.