ISRCTN69188731
Completed
Not Applicable
A prospective, open, randomized, multicenter study comparing the effects of everolimus versus mycophenolate sodium as compared to ciclosporin as maintenance therapy in renal allograft recipients, on chronic allograft damage and cardiovascular parameters.
Academic Medical Center (AMC), Renal Transplant Unit (The Netherlands)0 sites255 target enrollmentFebruary 14, 2006
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Renal transplant
- Sponsor
- Academic Medical Center (AMC), Renal Transplant Unit (The Netherlands)
- Enrollment
- 255
- Status
- Completed
- Last Updated
- 11 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. First or second renal transplant
- •2\. Female or male 18\-70 years old
- •3\. Cadaveric or non\-HLA identical living donor
- •4\. Understands risks and purpose of study
- •5\. Written informed consent
Exclusion Criteria
- •1\. Double kidney transplants, kidney\-pancreas transplants, 3rd or 4th transplant
- •2\. PRA \>50% historic or current
- •3\. Pregnancy or unwilling to use contraception during the study
- •4\. Cholesterol \>8\.5 mmol/l
- •5\. History of therapy resistance against HMG co\-reductase inhibitors
Outcomes
Primary Outcomes
Not specified
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