Safety of Sticker Pad Containing Essential Oil Containing Lavender and Ylang-ylang Oil Attached to the Collar for Decrease Blood Pressure in Healthy Volunteer
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 56
- 试验地点
- 1
- 主要终点
- Adverse reactions of the respiratory tract, skin, eye, and central nervous system
研究概览
简要总结
The aims of the study were to evaluate safety of sticker pads containing lavender and ylang ylang oil in healthy volunteers.
详细描述
The lavender and ylang ylang oil pad was attached to the shirts of healthy volunteers for 2 hours. The outcomes were evaluated before, during and 30 minutes after removal of the pad. Adverse reactions, irritation score, and quality of life were assessed. Blood pressure and pulse rate were also measured
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •age 18 to 60 years
- •no allergic history of lavender and ylang ylang oil
- •no dermatological diseases, immunocompromised diseases, seizures, asthma, or respiratory diseases.
排除标准
- •an unstable condition of other diseases
- •olfactory problems
- •pregnancy
- •lactation
研究组 & 干预措施
Sticker pads containing lavender and ylang ylang oil
Sticker pads , size 160 mm2, were produced by a certified ISO 9001 manufacturer and contained 0.3% lavender oil and 0.7% ylang ylang oil. The sticker pad was attached to the shirts of healthy volunteers for 2 hours. The outcomes were evaluated before, during and 30 minutes after removal of the pad.
干预措施: Sticker pads containing lavender and ylang ylang oil (Device)
结局指标
主要结局
Adverse reactions of the respiratory tract, skin, eye, and central nervous system
时间窗: 2 hours
The severity scores were 0 (no symptoms) to 3 (severe symptoms)
次要结局
- Irritation of eye, respiratory, other neurological, and toxicity reaction(2 hours)
- Diastolic blood pressure(2 hours)
- Pulse rate(2 hours)
- Systolic blood pressure(2 hours)
- Rhinoconjunctivitis quality of life questionnaire(2 hours)
研究者
Pornanong Aramwit, Pharm.D., Ph.D
Professor
Chulalongkorn University