Does artificial sweetener affect energy expenditure and food intake?

Not Applicable

Completed

• Conditions: Obesity; Diet and Nutrition - Obesity

• Registration Number: ACTRN12614000879662
• Lead Sponsor: niversity of South Australia

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-08-19
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

Normal or overweight (BMI 18-35 kgm-2)
- Non-diabetic and no gastrointestinal diseases
- Literate and able to report food intake

Exclusion Criteria

- Taking medications that affect metabolism and appetite
- Food intolerance or allergies
- Vegetarian

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Energy expenditure and respiratory quotient (RQ) using an indirect calorimetry TrueMax2400, ParvoMedic[30min pre-preload ingestion (at rest), and 0-30min, 45-75min and 90-120min after preload ingestion];Appetite via visual analog scales[Pre- and post-preload ingestion, and pre- and post-meal challenged after energy expenditure assessment];Food intake measured through self-administered food intake diary with instructions[At meal challenge after energy expenditure measurement, and for the remaining day through food record.]

Secondary Outcome Measures

Name	Time	Method
Habitual food intake is assessed using a multi-pass 24-hour dietary recall method[At baseline];Eating behaviour using Three Factor Eating Questionnaire[At baseline];Habitual physical activity using a validated questionnaire, Johansson G & Westerterp KR (2008) Assessment of the physical activity level with two questions: validation with doubly labeled water. Int J Obes 32, 1031-1033.[At baseline];Body weight and body fat percentage using a bio-electrical impedence scale[At baseline and before each indirect calorimeter measurement]