Nutritional Strategies for Optimizing Adaptations and Recovery Following Training 'Low'.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 9
- 主要终点
- Muscle protein fractional synthetic rate (FSR)
研究概览
简要总结
A randomized interventions study using a crossover design. Ten well trained triathletes or bikeriders will be included for to undergo two trail separated by about 3 weeks. The night before the trail each subject will performe a high intense interval trainings session on an ergometer bike. during the night an infusion of aminoacid tracers will be initiated. The subject is woken at 6.30 a.m. Blood samples and a musclebiopsy will be collected prior to the morning bike ride at 8.00a.m. Immediately before the morning bike ride is started the subject will ingest a drink of 0,5g protein or a non-caloric placebo (random order). During the bike ride and the following 4,5 hours blood will be drawn with regular intervals. at time point 0, 60 and 180 min after the training session biopsies are collected.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Health Services Research
- 盲法
- Single (Participant)
盲法说明
Masking was done by providing similar tasting drinks at both trails. One was placebo, one was protein a drink
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Healthy well-trained triathletes or cyclists
- •VO2max > 55 ml O2/kg/min
- •Training and has been training more than 7 times a week the last 6 months.
排除标准
- •VO2max < 55 ml O2/kg/min
- •Has chronic disease
- •has incjected with tracer on a previous occasion.
结局指标
主要结局
Muscle protein fractional synthetic rate (FSR)
时间窗: FSR was measure over at time period of six hours
次要结局
- Muscle signalling(Determined in biopsies sampled before and immediatly after 90min exercise in addition to one and four hours after exercise.)
- Nitrogen excretion(Urine is collected during two periods. Collection period one: 12 hours prior to morning exercise. Collection period 2: During and four hours following exercise. Blood samples is drawn repeatedly from before to four hours after exercise.)
- Tracer kinetics dilution model(six hours)
研究者
Mette Hansen
Assistant professor, PhD
University of Aarhus