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An Observational Study of Local Relapse After High Grade Osteosarcoma

Recruiting
Conditions
Osteosarcoma
Registration Number
NCT06017518
Lead Sponsor
Istituto Ortopedico Rizzoli
Brief Summary

multicenter retrospective and prospective study in patients with high-grade osteosarcoma

Detailed Description

This is a multicenter retrospective and prospective study that will analyze all cases with of diagnosis of local relapse in high-grade osteosarcoma from 01 January 1980 and all new cases referring to each participant site.

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
150
Inclusion Criteria
  • Patients who experienced LR as first event of recurrence after treatment for localized high-grade osteosarcoma of bone, including cases with synchronous lung metastases
  • Adequate patient compliance to follow-up visits
  • Written informed consent prior to any study-specific analysis and/or data collection
  • No age limits
Exclusion Criteria
  • Cases of LR demonstrated after > 3 months after metastatic disease
  • Impossibility to ensure adequate compliance

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
post local relapse survival24 months follow up

the aim of the study is to analyse the factors influencing post local relapse survival

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (2)

Azienda Ospedaliero-Universitaria Pisana

🇮🇹

Pisa, PI, Italy

IRCCS Istituto Ortopedico Rizzoli

🇮🇹

Bologna, BO, Italy

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