Laser-Assisted Versus Conventional Intracytoplasmic Sperm Injection
- Conditions
- Infertility, MaleInfertility
- Registration Number
- NCT00114725
- Lead Sponsor
- Shady Grove Fertility Reproductive Science Center
- Brief Summary
Laser-assisted intracytoplasmic sperm injection (ICSI) has been suggested as a more effective alterative to conventional ICSI when this method of insemination is indicated for patients undergoing in vitro fertilization (IVF). Laser-assisted ICSI differs from conventional ICSI in that a laser is used to drill a small hole through the hard outer coating surrounding an egg before the injection needle containing a single sperm is inserted into the egg. The hole eliminates compression of the egg that normally occurs with conventional ICSI, and thus may reduce the chance of damage. Laser-assisted ICSI is hypothesized to result in increased egg survival, and perhaps improved embryo quality, compared to conventional ICSI.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 60
- Diagnosis of infertility
- Scheduled for IVF with ICSI
- Retrieval of fewer than 6 mature oocytes
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- FACTORIAL
- Primary Outcome Measures
Name Time Method oocyte survival rate 1 day after ICSI
- Secondary Outcome Measures
Name Time Method normal fertilization rate 1 day after ICSI embryo fragmentation rates 2 and 3 days after ICSI embryo compaction rate through day 7 after ICSI embryo cell numbers 2 and 3 days after ICSI blastocyst formation rate through day 7 after ICSI
Trial Locations
- Locations (1)
Shady Grove Fertility Reproductive Science Center
🇺🇸Rockville, Maryland, United States