the Predictive Value of neutrophil-to Lymphocyte Ratio on Preeclampsia- Eclampsia
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Preeclampsia
- Sponsor
- Zekai Tahir Burak Women's Health Research and Education Hospital
- Enrollment
- 600
- Locations
- 1
- Primary Endpoint
- the effect of neutrophil lymphocyte ratio in preeclampsia eclampsia
- Last Updated
- 12 years ago
Overview
Brief Summary
Neutrophil/lymphocyte ratio (NLR) is a marker of systemic inflammation and endothelial dysfunction. In recent years, it has been reported that the individual components of the differential white cell count, specifically the neutrophil and lymphocyte counts,may have clinical utility in predicting diseases. An elevated NLR has been shown to be a prognostic indicator in various malignancies. İn the literature, many studies have been shown that NLR have predictive value in determining the prognosis of various diseases (cardiac or noncardiac diseases ). However, little is known about the predictive values of NLR in pregnancy complications. This study aimed to evaluate the potential predictive value of NLR in preeclampsia- eclampsia.
Detailed Description
In recent years, have been reported that the individual components of the differential white cell count, specifically the neutrophil and lymphocyte counts, may have clinical utility in predicting diseases. An elevated NLR has been shown to be a prognostic indicator in various malignancies. İn the literatüre have been shown that NLR have predictive value in determining the prognosis of various diseases (cardiac or noncardiac diseases.However, little is known about the predictive values of NLR and PLR in gestational DM, preeclampsia and the other pregnancy complications. Retrospective data were collected for patients who was diagnosed with , preeclampsia- eclampsia, The NLR was defined as the absolute neutrophil count divided by the absolute lymphocyte count.
Investigators
Ayse Kirbas
Ayse Kirbas, MD
Zekai Tahir Burak Women's Health Research and Education Hospital
Eligibility Criteria
Inclusion Criteria
- •pregnant women who developing preeclampsia eclampsia at pregnancy
Exclusion Criteria
- •Known chronically maternal disease multiple pregnancy older than 40 years old
Outcomes
Primary Outcomes
the effect of neutrophil lymphocyte ratio in preeclampsia eclampsia
Time Frame: up to 6 months
during 6 months ,the patients who was recorded with preeclampsi/eclampsia at our hospital ,first trimester whole blood count was taken and neutrophil lymphocyte ratio was calculated and recorded