The use of aerobic exercise to augment training of motor skill in stroke rehabilitatio

Not Applicable

• Conditions: Nervous System Diseases; Stroke; Stroke rehabilitation

• Registration Number: ISRCTN24868616
• Lead Sponsor: meå University (Sweden)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2011-04-05
• Last Update Posted: 21 August 2023
• Study Completion: 2024-06-30

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 46

Inclusion Criteria

1. An approval from the patient's physician
2. Aged 18 years and over, either sex
3. First time stroke
4. Stroke =3 months ago
5. BL-motor assessment score less than or equal to 45
6. Able to pick up and release a tennis ball 3 times in 1 minute
7. Mini-mental state examination (MMSE) score greater than or equal to 24
8. Able to cycle on a stationary bicycle 4 x 5 minutes with 1 minute rest between intervals at an exertion level corresponding to 13 on Borgs RPE-scale

Exclusion Criteria

1. Participants in both groups missing 3 hours or more of training
2. Participants in the intervention group missing more than one session of aerobic exercise, or from two or more interrupted aerobic exercise sessions lacking the same amount of aerobic exercise.
3. Other brain injury than stroke, e.g. intracranial haemorrhage caused by aneurysmal rupture or trauma
4. Neurological disorder such as Parkinson's disease or peripheral nerve damage
5. Stroke affecting brainstem and/or cerebellum
6. Previous participation in constraint-induced movement therapy (CIMT)
7. Current participation in other stroke treatment directed at motor skill
8. Injection of anti-spasticity drugs into upper extremity musculature within the past 3 months

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Motor skill by BL-motor assessment, at baseline and after intervention