Effect of Functional Task Exercise Program on Older Adults with Cognitive Impairment at Risk of Alzheimer Disease
Not Applicable
Completed
- Conditions
- Mild cognitive impairmentNeurological - Alzheimer's disease
- Registration Number
- ACTRN12610001025022
- Lead Sponsor
- James Cook University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
1) Memory/cognitive complaint; (2) Objective cognitive impairment in 1 or more domains; but with (3) intact personal selfcare functions; (4) Absence of Dementia
Exclusion Criteria
(1) History of brain lesion/ psychoactive substance abuse/co-morbid medical condition associated with cognitive/ functional decline; (2) Clinically significant depression; (3) significant impairment of vision, hearing or communication(4) Medical conditions render patients unable to engage in physical activity, such as severe cardiac failure
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Chinese version of Neurobehavioral Cognitive Status Examination[Baseline, at completion (10 weeks) and 3 months after completion of intervention];Specific cognitive functions: Trail making test A and B to assess visual scanning mental flexibility, and executive functions. Verbal fluency test to assess speed of answer; mental organization; search strategies, and short- and long-term Memory. Auditory-Verbal Learning Test to assess evaluates immediate memory span, new learning, susceptibility to interference, retention of memory and recognition memory. Problems in Everyday Living Test to assess ability of practical problem solving related to everyday life.[Baseline, at completion (10 weeks) and 3 months after completion of intervention]
- Secondary Outcome Measures
Name Time Method Health status & Quality of Life: Medical Outcomes 12-Item Short-Form (SF-12) Health Survey[Baseline, at completion (10 weeks) and 3 months after completion of intervention];Functional Status: Activities of Daily Living Questionnaire and Lawton Instrument Activities of Daily Living Scale to assess functional level.<br>Zarit Caregiver Burden Interview to measure the carer burden[Baseline, at completion (10 weeks) and 3 months after completion of intervention]