IRCT20100706004329N9招募中3 期
Comparison of metformin and placebo on breast mammography density in healthy women over 40 years
试验速览
- 阶段
- 3 期
- 状态
- 招募中
- 入组人数
- 146
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 40 years 至 no limit（—）
- 性别
- Female
入选标准
- •Female gender
- •Age over 40 years
排除标准
- •Suspicion of malignancy
- •Used of drugs that affect metabolic status, such as weight, glucose, and lipid-lowering agents During the study or three months before the study
- •History of breast cancer
- •Proven or suspected pregnancy and lactation during the intervention
- •Other medical conditions, such as cardiovascular disease, epilepsy, renal or hepatic disorders
- •Contraindications for metformin use (such as hypersensitivity to biguanides, acidemia, heart disease, alcohol consumption, gastroparesis, hepatic disease, hyperthyroidism or hypothyroidism, severe iron deficiency anemia, renal impairments)
- •History of unwanted and intolerable side effects of metformin (such as abdominal pain, chest pain, chills, cholestasis, diarrhea, dizziness, increased liver enzymes, severe headache, hepatitis, hypoglycemia, megaloblastic anemia, myalgia, nausea, Palpitations, rash, rash, vomiting)
- •Suffering from hormonal disorders and metabolic diseases such as hypo or hyperthyroidism, metabolic syndrome, diabetes, severe hyperlipidemia, galactorrhea
研究者
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