NCT01297426撤回不适用
Leptin Signaling in Humans
适应症
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 试验地点
- 1
- 主要终点
- Westerns / activation of signaling pathways (uo to two hours after treatment)
研究概览
简要总结
Obesity does not respond to high circulating levels of the hormone leptin. This study is aiming at finding out why this happens and open new avenues for treatment of obesity.
详细描述
Ex vivo and in vitro identification and study of leptin signaling pathways in commercially available cell lines serum/ plasma samples and discarded tissues from humans.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •men and women
- •ages 18 to 65
- •BMI ranges between 20 and 45 kg/m2
排除标准
- •subjects requiring special diets
- •history of illness other than obesity of diabetes
- •taking medications known to influence glucose metabolism
- •subjects with history of anaphylactic reaction or hypersensitivity to e. coli derived proteins or anesthetic agents
- •women who are breastfeeding, pregnant or wanting to become pregnant
- •subjects with bleeding dyscrasia or poor wound healing
结局指标
主要结局
Westerns / activation of signaling pathways (uo to two hours after treatment)
时间窗: 04/01/2016
次要结局
未报告次要终点
研究者
研究点 (1)
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