ISRCTN16562415
Completed
N/A
The impact of dietary interventions for irritable bowel syndrome on luminal microbiota, symptoms, nutrient intake and quality of life: a randomised controlled trial
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Irritable bowel syndrome
- Sponsor
- King's College London
- Enrollment
- 69
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
2020 Results article in https://pubmed.ncbi.nlm.nih.gov/32433273/ results (added 07/08/2020)
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Men and women aged 18\-65 years with diarrhoea\-predominant IBS (IBS\-D), mixed\-type IBS (IBS\-M) or unsubtyped IBS (IBS\-U) based on Rome III criteria who do not have a major medical condition (diabetes, psychiatric or current eating disorders), gastrointestinal disease (e.g. inflammatory bowel disease, coeliac disease) or history of previous GI surgery, except cholecystectomy and haemorrhoidectomy
- •2\. Individuals able to give informed consent
- •3\. Individuals naive to the dietary intervention
Exclusion Criteria
- •1\. Females who report to be pregnant or lactating
- •2\. Consumption of antibiotics, prebiotics or probiotics (in food products or as supplements) in the last 4 weeks prior to, or during the study
- •3\. Use of unpermitted medications
- •4\. Participants who have received bowel preparation for investigative procedures in the 4 weeks prior to the study
- •5\. Participants who have had changes to IBS medications or dose in the 4 weeks prior to the study
- •6\. Less than 2 days of at least moderate abdominal pain or discomfort in the screening week
- •7\. Individuals with additional specific dietary needs
- •8\. Individuals with excess alcohol or caffeine intake as assessed by diet questionnaires as these substances may confound symptom results
Outcomes
Primary Outcomes
Not specified
Similar Trials
Completed
N/A
Dietary interventions for irritable bowel syndromeISRCTN02275221King's College London (UK)95
Completed
N/A
Oral rehabilitation coupled with dietary intervention for older patientsutritionNutritional, Metabolic, EndocrineISRCTN66118345Queen's University Belfast (UK)54
Completed
N/A
Dietary Interventions in inflammatory bowel disease (IBD)Topic: GastroenterologySubtopic: GastroenterologyDisease: All GastroenterologyDigestive SystemInflammatory bowel disease (IBD)ISRCTN17061468King's College London52
Completed
N/A
Efficiency of following Mediterranean diet recommendations in the real world in the incidence of gestational diabetes mellitusISRCTN13389832The Health Research Institute of San Carlos (Instituto de Investigación Sanitaria San Carlos)1,066
Completed
N/A
Delivered Dietary Intervention for Children With Irritable Bowel SyndromeIrritable Bowel SyndromeAbdominal PainNCT01339117Baylor College of Medicine40