Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) Could Decrease the Incidence of Oxygen Desaturation During Suspension Laryngoscopy: a Randomized Controlled Trial (Optilaryngo)

Not Applicable

Completed

• Conditions: Pharynx; Anomaly; Apnea, Postanesthetic; Desaturation of Blood; Larynx Disease; Anesthesia; Apnea
• Interventions: Device: optiflow

• Registration Number: NCT03843580
• Lead Sponsor: University Hospital, Caen

Brief Summary

Suspension laryngoscopy is realised during apnea. In effect, surgeons are in the mouth of the patient and we can't have access at the aiways.

So investigators like to use a Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) to increase time of apnea and decrease the impact of oxygen desaturation.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2019-02-13
• Study First Submitted QC: 2019-02-14
• Study First Posted: 2019-02-18
• Study Start: 2019-04-23
• Status Verified: 2020-02
• Primary Completion: 2021-02-10
• Study Completion: 2022-02-10
• Last Update Submitted: 2022-02-17
• Last Update Posted: 2022-02-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• suspension laryngoscopy

Exclusion Criteria

• THRIVE contraindication:
• epistaxis
• undrained pneumothorax
• Recent gastroesophageal surgery (1months)
• Skull Fractures

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
oxygenation optiflow	optiflow	optiflow oxygenation during apnea

Primary Outcome Measures

Name	Time	Method
desaturation defined as the number of patient who presented at least one desaturation during suspension laryngoscopy	Two hours	the number of patient who presented at least one desaturation during suspension laryngoscopy. An oxygen desaturation define like SpO2\<96%

Secondary Outcome Measures

Name	Time	Method
hypoxemia (decrease the number of Hypoxemia event define like SpO2<90%)	2 hours	Decrease the number of Hypoxemia event define like SpO2\<90%
side effect	2 hours	decrease the number of side effects

Trial Locations

Locations (2)

Centre François Baclesse; 🇫🇷 Caen, France

CaenUH; 🇫🇷 Caen, Normandie, France