Randomised controlled clinical study to evaluate the efficacy of triphalabadriplakshadi kwath parisheka in the in management of ahiputana ( Diaper rash)in children
试验速览
- 阶段
- 2/3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 93
- 试验地点
- 1
- 主要终点
- strava(Discharge) will be decreased
研究概览
简要总结
-
Ahiputana (Diaper rash ) is a common in infants and very common feeding baby . it can be corelatted with diap-er rash disease whivh is kapharaktaj.
-
Predominant disorder mentioned in ayurvedik textbook
-
It comes under different types of Kshudrarog
4)It is caused due to unhygienic conditions like absence of proper cleaning after defecation and urination
-
Diaper rash is caused by B proteus in fecal matter.
-
In that diaper region inflammatory disorder characterized by the development of erythema, papules and sometimes vesiculation with scaling is seen diaper rash
-
It involves uppermost layer of the epidermis the stratum corneum and develops as a diapered skin.
8)The over hydration of skin promotes the development of higher PH than skin PH.Stool enzymes like protease and lipase have increased their activity which leads to increase in PH.and causes skin break down. In addition mechanical friction from the diaper cause skin break down.
PREVALANCE
It is common dermatological disorder of infants resulting in a large number of visits to physician each year. the prevalence in infants has been estimated to be 4 to 35%
RATIONALE OF STUDY
Diaper dermatitis is common frustrating disorder and occurs in children as the children can not telerate the pain or itching due to napkin rash so they cry for long time which hamper the mentality of parents. In this condition children are so irritable they avoid their daily food intake and results in weight loss of children.
As skin of children is very sensitive, the conventional treatment in modern medicine has side effect such as allergic reaction, irritation , other skin diseases.
So Ayurvedic medicine Triphalabadariplakshadi Kwath Parishek would be easy to follow, provide result in short duration and cost effective as well as easy for application and also free from side effects in managment of Ahiputana in children
NULL HYPOTHESIS(H0)- Triphalabadariplakshadi Kwath Parisheka is not effective in managment of Ahiputana in children.
ALTERNATE HYPOTHESIS(H1)-Triphalabadriplakshadi Kwath Parisheka is effective in managment of Ahiputana in children.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 4.00 Month(s) 至 2.00 Year(s)（—）
- 性别
- All
入选标准
- •1.Children diagnosed of Ahiputana(Diaper rash)with the presenting symptoms like strav,irritability,redness.
- •2.Symptoms of Ahiputana (Diaper rash)within 10 days.
- •3.Children in between the age group of 4 months to 2 year irrrespective of gender,socioeconomic religion, diet.
排除标准
- •1.Children above the age group of 2 year and below 4months 2.Children suffering from any other systemic disorder eg.acutegastroenteritis with dehydration,helmenthes infection,lactogen intolerance ,secondary infection.etc.
- •3.Symptoms of Ahiputana (Diaper rash) more than 10 days.
- •4.Children who have other generalised skin infections other than Ahiputana(Diaper rash).
结局指标
主要结局
strava(Discharge) will be decreased
时间窗: 10 days
Irritability(cry) will be decreased
时间窗: 10 days
Sthanik Varna (Erythema)will be decreased
时间窗: 10 days
次要结局
- Sthanik vyapti(region of rash) will be decreased(10 days)
研究者
DrJayshri Ram Motegaonkar
Chhatrapati shahu Maharaj Shikshan sanstha