A randomized comparison of Pericapsular nerve group (PENG)block and combined Pericapsular nerve group (PENG) with Lateral Femoral cutaneous nerve of thigh for Postoperative analgesia in Hip fracture surgery

Phase 2

• Conditions: eck of femur fracture.; Hip fracture,Pericapsular nerve group (PENG) block,elderly falls,opioid consumption,postoperative opioid.

• Registration Number: TCTR20211203001
• Lead Sponsor: Faculty of medicine ,Chiangmai university.

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-12-03
• Study Completion: 2023-06-01
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: nknown
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

Aged 55 years or above.
Body weight 35 kg. or above.
ASA classification l-lll
closed fracture neck of femur.

Exclusion Criteria

- Previous hip surgery
- Inability to understand and report pain severity
- Decreased mental status or confusion state
- Uncontrolled cardiovascular and respiratory diseases
- Hepatic or renal failure
- Chronic opioids use
- Allergy to bupivacaine or other medications used in the protocol
- Contraindications for spinal anesthesia: patient refusal, coagulopathy, increased intracranial pressure, local skin infection at needle insertion site, preload- and afterload-dependent cardiovascular disease (eg. aortic stenosis), intravascular volume depletion, sepsis, abnormal spine anatomy
- Contraindications for all PNBs: patient refusal, preexisting neurological deficit, abnormal anatomy of back or inguinal area

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
opioid comsumption,effectiveness of ultrasound-guided Pericapsular nerve group (PENG)block and combined Pericapsular nerve group (PENG) with Lateral Femoral cutaneous nerve of thigh in hip fracture 24 hours after end of the intervention dose of opioid comsumption.

Secondary Outcome Measures

Name	Time	Method
the reduce of motor weakness 24 hours after end of the intervention Oxford muscle strength grading.,efficacy of ultrasound-guided pericapsular nerve group (PENG) block combined pericapsular nerve group block (PENG) with lateral femoral cutaneous nerve (LFCN) block (imaging time + needling time Performance timeand number of needle punctures are recorded,compare safety of ultrasound-guided pericapsular nerve group (PENG) block combined pericapsular nerve group block (PENG) with lateral femoral cutaneous nerve (LFCN) block 72 hours after end of the intervention evaluated by recording incidences of complications of the PNBs including intravascular injection, paresthesia, local anesthetic systemic toxicity (LAST)