Effect of neuromuscular blockade and reversal by sugammadex versus neostigmine on breathing when hypoxic or hypercapnic in volunteers

Completed

• Conditions: perioperatieve verslapping; perioperative muscle relaxation

• Registration Number: NL-OMON46872
• Lead Sponsor: eids Universitair Medisch Centrum

Brief Summary

Trial is onging in other countries

Detailed Description

Not available

Study Timeline

• Study Completion: 2018-12-11
• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 36

Inclusion Criteria

Healthy male volunteers aged 18 and older with a body mass index < 30 kg/m2.

Exclusion Criteria

Known or suspected neuromuscular disorders impairing neuromuscular function; allergies to muscle relaxants, anesthetics or narcotics; a (family) history of malignant hyperthermia or any other muscle disease; any medical, neurological or psychiatric illness (including a history of anxiety).

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Magnitude of the hypoxic and hypercapnic ventilatory responses.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>NA</p><br>