Clinical Performance of Two Daily Disposable Soft Contact Lenses

Not Applicable

Completed

Interventions: Device: Verofilcon A contact lenses
Device: Nesofilcon A contact lenses

Brief Summary: The purpose of this study is to compare the clinical performance of PRECISION1 contact lenses with Biotrue contact lenses.

Detailed Description: Subjects will be expected to attend 3 visits. Subjects will be expected to wear their study contact lenses every day for at least 10 hours per day over an 8-day period for each study lens type. The total duration of a subject's participation in the study will be up to 22 days.

Recruitment & Eligibility

Inclusion Criteria

Successful wear of spherical soft contact lenses with at least 3 months wearing experience, with a minimum wearing time of 5 days per week and 10 hours per day.
Willing to wear habitual spectacles for vision correction when study lenses are not worn, as needed.
Willing to wear contact lenses for at least 16 hours on the day prior to Visit 2 and the day prior to Visit 3.
Other protocol-defined inclusion criteria may apply.

Key

Exclusion Criteria

Participation in a clinical trial within the previous 30 days or currently enrolled in any clinical trial.
Habitual PRECISION1, Biotrue, and DAILIES TOTAL1 contact lens wear.
Monovision and multifocal lens wear.
Other protocol-defined exclusion criteria may apply.

Arm && Interventions

Group	Intervention	Description
PRECISION1, then Biotrue	Verofilcon A contact lenses	Verofilcon A contact lenses worn first, with nesofilcon A contact lenses worn second, as randomized. Each study lens type will be worn bilaterally (in both eyes) at least 10 hours per day for 8 -0/+3 days. A fresh pair of lenses will be worn each day.
PRECISION1, then Biotrue	Nesofilcon A contact lenses	Verofilcon A contact lenses worn first, with nesofilcon A contact lenses worn second, as randomized. Each study lens type will be worn bilaterally (in both eyes) at least 10 hours per day for 8 -0/+3 days. A fresh pair of lenses will be worn each day.
Biotrue, then PRECISION1	Verofilcon A contact lenses	Nesofilcon A contact lenses worn first, with verofilcon A contact lenses worn second, as randomized. Each study lens type will be worn bilaterally (in both eyes) at least 10 hours per day for 8 -0/+3 days. A fresh pair of lenses will be worn each day.
Biotrue, then PRECISION1	Nesofilcon A contact lenses	Nesofilcon A contact lenses worn first, with verofilcon A contact lenses worn second, as randomized. Each study lens type will be worn bilaterally (in both eyes) at least 10 hours per day for 8 -0/+3 days. A fresh pair of lenses will be worn each day.

Primary Outcome Measures

Name	Time	Method
Least Squares Mean Distance Visual Acuity (VA) With Study Lenses	Day 8 (-0/+3 days), each study lens type	Visual Acuity (VA) was collected for each eye individually with study lenses in place using a letter chart. VA was measured in logarithm of the minimum angle of resolution (logMAR). A logMAR value of 0 corresponds to 20/20 Snellen acuity (normal distance eyesight), with a lower logMAR value indicating better visual acuity.

Secondary Outcome Measures

Name	Time	Method

Locations (8): Tallahassee Eye Center
🇺🇸
Tallahassee, Florida, United States
Kindred Optics at Maitland Vision
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Maitland, Florida, United States
Franklin Park Eye Center PC
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Franklin Park, Illinois, United States
Heart of America Eye Care
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Shawnee Mission, Kansas, United States
Complete Eye Care Of Medina
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Medina, Minnesota, United States
ProCare Vision Centers, Inc.
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Granville, Ohio, United States
Clarke EyeCare Center
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Wichita Falls, Texas, United States
Stine Eye Center
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Weston, Wisconsin, United States