Giving medicine dexamethasone two times as compared to one time only to decrease pain and edema after major surgery of the abdomen.
Phase 3
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2024/06/069469
- Lead Sponsor
- All India Institute of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Adult patients of ASA physical status I and II scheduled for elective major open abdominal surgery
Exclusion Criteria
Diabetic
COPD or asthma
History of peptic ulcer disease
Current or recent steroid intake within last 4 weeks
Any concurrent infection
BMI more than 35
Pregnancy and lactation
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method a)mean post-operative CRP level <br/ ><br>b)mean post-operative VAS score (by asking patients to grade the worst pain experienced by them during the preceding 12 hours) <br/ ><br>Timepoint: a)postoperative days 1 and 3 and 5 <br/ ><br>b)recorded twice daily at 8-9 am and 8-9 pm up to postoperative day 5
- Secondary Outcome Measures
Name Time Method