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Clinical Trials/NCT01830998
NCT01830998
Unknown
Not Applicable

Study of Cognitive Dysfunction and Diabetes

Wuhan General Hospital of Guangzhou Military Command3 sites in 1 country400 target enrollmentJanuary 2012
ConditionsDementiaDMMCI

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Dementia
Sponsor
Wuhan General Hospital of Guangzhou Military Command
Enrollment
400
Locations
3
Primary Endpoint
MMSE Olfactory function dementia
Last Updated
11 years ago

Overview

Brief Summary

The rate of cognitive decline due to ageing is increased 1.5-fold to 2.0-fold in individuals with type 2 diabetes.There are no established specific treatment measures to prevent or ameliorate cognitive impairments in patients with diabetes. we want to detecte early clinical dementia in diabete.

Detailed Description

Clinically relevant cognitive decrements in relation to diabetes mainly occur during two crucial periods in life: the period of brain development in childhood, and the period when the brain undergoes neurodegenerative changes associated with ageing.Potential leads for treatment are to optimise glycaemic control and avoid and treat vascular risk factors.we want to detecte early clinical dementia in diabete by MMSE and Olfactory function.

Registry
clinicaltrials.gov
Start Date
January 2012
End Date
December 2014
Last Updated
11 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Wuhan General Hospital of Guangzhou Military Command
Responsible Party
Principal Investigator
Principal Investigator

zhipeng xu

doctor

Wuhan General Hospital of Guangzhou Military Command

Eligibility Criteria

Inclusion Criteria

  • Patients with type 2 diabetes(Age\>50 years)

Exclusion Criteria

  • with stroke or other complications.

Outcomes

Primary Outcomes

MMSE Olfactory function dementia

Time Frame: 2 years

MMSE,Olfactory function and PET(fMRI) were observed.

Study Sites (3)

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