Study of Cognitive Dysfunction and Diabetes
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 400
- 试验地点
- 3
- 主要终点
- MMSE Olfactory function dementia
研究概览
简要总结
The rate of cognitive decline due to ageing is increased 1.5-fold to 2.0-fold in individuals with type 2 diabetes.There are no established specific treatment measures to prevent or ameliorate cognitive impairments in patients with diabetes. we want to detecte early clinical dementia in diabete.
详细描述
Clinically relevant cognitive decrements in relation to diabetes mainly occur during two crucial periods in life: the period of brain development in childhood, and the period when the brain undergoes neurodegenerative changes associated with ageing.Potential leads for treatment are to optimise glycaemic control and avoid and treat vascular risk factors.we want to detecte early clinical dementia in diabete by MMSE and Olfactory function.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 50 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients with type 2 diabetes(Age>50 years)
排除标准
- •with stroke or other complications.
结局指标
主要结局
MMSE Olfactory function dementia
时间窗: 2 years
MMSE,Olfactory function and PET(fMRI) were observed.
次要结局
未报告次要终点
研究者
zhipeng xu
doctor
Wuhan General Hospital of Guangzhou Military Command