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Clinical Trials/NCT03755895
NCT03755895
Completed
Phase 2

Randomized Trial Comparing the Hypnosis Versus Standard Care of Anxiety and Pain in Patients With Brachytherapy

Institut de Cancérologie de Lorraine1 site in 1 country68 target enrollmentNovember 2, 2019

Overview

Phase
Phase 2
Intervention
formal hypnosis
Conditions
Cancer
Sponsor
Institut de Cancérologie de Lorraine
Enrollment
68
Locations
1
Primary Endpoint
Anxiety evaluation
Status
Completed
Last Updated
7 months ago

Overview

Brief Summary

Formal hypnosis is a non-drug technique known to decrease anxiety and pain during the preoperative procedure.

In brachytherapy, the practice of hypnosis has been shown to be feasible and beneficial for patients treated for prostate cancer The goal of the study is to demonstrate the added value of hypnosis during a brachytherapy detachment by improving the comfort of the patient.

The investigators want to evaluate the contribution of hypnosis during brachytherapy detachment by quantifying the anxiety and pain felt by the patient during the procedure.

Registry
clinicaltrials.gov
Start Date
November 2, 2019
End Date
May 25, 2022
Last Updated
7 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Institut de Cancérologie de Lorraine
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Adult patients ≥ 18 and ≤ 80 years
  • Patients expected to benefit a brachytherapy detachment Under KALINOX® for one of the types of applications described below:
  • Deep interstitial application: anal canal, vagina, vulva
  • Gynecological application: mold, Utrecht® system or Venezia® system
  • Ability to provide written informed consent
  • Patients affiliated to the social security system

Exclusion Criteria

  • Minor and patients over 80 years old
  • Patients with major hearing loss
  • Patients who had recent ocular surgery with oculiare gas injection.
  • Patients suffering from psychotic disorders, and dementias.
  • Patients who do not understand the French language
  • Patients under guardianship or deprived of liberty
  • Patients with a contraindication to the administration of KALINOX®

Arms & Interventions

experimental

patients to benefit from brachytherapy detachment under KALINOX and formal hypnosis

Intervention: formal hypnosis

experimental

patients to benefit from brachytherapy detachment under KALINOX and formal hypnosis

Intervention: Kalinox

active comparator

patients to benefit from brachytherapy detachment under KALINOX

Intervention: Kalinox

Outcomes

Primary Outcomes

Anxiety evaluation

Time Frame: 1day

The patient's anxiety will be assessed using the State-Trait Anxiety Inventory scale ("state of anxiety") before premedication (in the bedroom) and immediately after the brachytherapy detachment (in the examination room) during brachytherapy detachment using two care management: standard care versus standard care with formal hypnosis. The State-Trait Anxiety Inventory (STAI) is a commonly used measure of trait and state anxiety (Spielberger et al, 1983). The scale include 20 items. Higher scores indicate greater anxiety

Secondary Outcomes

  • Realization of the brachytherapy detachment(1day)
  • Time of brachytherapy detachment(1day)
  • Anxiety evaluation(1 day)
  • Pain evaluation: numeric scale(1 day)
  • Patient's perception of the care(1day)

Study Sites (1)

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