Bone Marrow Cells in Myocardial Infarction
Phase 2
Completed
- Conditions
- Acute Myocardial Infarction
- Registration Number
- NCT00363324
- Lead Sponsor
- University of Oulu
- Brief Summary
This study is aimed to assess the effect of bone marrow cells on arrhythmia risk variables in patients with a acute myocardial infarction.
- Detailed Description
This is a randomized, double-blinded study, where patients treated with thrombolytic therapy for acute myocardial infarction are randomized to receive bone-marrow derived stem cells or sham-infusion at the time percutaneous coronary intervention of the target vessel. The end-points are many arrhythmia risk variables, suchs as heart rate variability, T-wave alternans and many ECG variables as well as systolic and diastolic left ventricular function.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
- Acute ST-elevation myocardial infarction treated with thrombolytic therapy
Exclusion Criteria
- Indication for rescue PCI, severe clinical heart failure, age <18 years
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Arrhythmia risk variables left ventricular function restenosis assessed by IVUS
- Secondary Outcome Measures
Name Time Method exercise tolerance
Trial Locations
- Locations (1)
University of Oulu
🇫🇮Oulu, Finland