NCT00363324已完成2 期
Effects of Autologous Bone Marrow Celss on Acute ST-Elevation Myocardial Infarction
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 100
- 试验地点
- 2
- 主要终点
- Arrhythmia risk variables
研究概览
简要总结
This study is aimed to assess the effect of bone marrow cells on arrhythmia risk variables in patients with a acute myocardial infarction.
详细描述
This is a randomized, double-blinded study, where patients treated with thrombolytic therapy for acute myocardial infarction are randomized to receive bone-marrow derived stem cells or sham-infusion at the time percutaneous coronary intervention of the target vessel. The end-points are many arrhythmia risk variables, suchs as heart rate variability, T-wave alternans and many ECG variables as well as systolic and diastolic left ventricular function.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Acute ST-elevation myocardial infarction treated with thrombolytic therapy
排除标准
- •Indication for rescue PCI, severe clinical heart failure, age <18 years
结局指标
主要结局
Arrhythmia risk variables
left ventricular function
restenosis assessed by IVUS
次要结局
- exercise tolerance
研究者
研究点 (2)
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