Virtual Environment to Aid Cognitive Stimulation of Elderly People With Early Alzheimer's

Not Applicable

Completed

• Conditions: Alzheimer Disease
• Interventions: Other: Virtual Environment

• Registration Number: NCT04919005
• Lead Sponsor: University of Mogi das Cruzes

Brief Summary

This research was carried out with the objective of verifying the possibility of intervention through cognitive training protocols to assist in the stimulation of neurons and to delay the degradation resulting from Alzheimer's disease in its initial phase. The specific objective of this research was to develop and validate a virtual environment of games (called SorrisoTur) that allows the intervention of cognitive training.

Detailed Description

SorrisoTur encompasses cognitive training concepts and protocols in playful situations, which were coded in the form of 2D mini-games that are run on a computer connected to the Web, and designed to stimulate cognitive domains, such as memory, executive functions, spatial-visual skills, language (expression, comprehension, reading, and writing) and personality/behavior. For the comparison of results, three groups were created; one group of elderly people with Alzheimer's disease at an early stage, one group formed by healthy elderly, and another group with young people and applied Mini-Mental State Examination (MMSE) and Wechsler Intelligence Scale for Adults (WAIS-III) before and after of interventions with the games.

Study Timeline

• Study Start: 2016-07-01
• Primary Completion: 2017-04-30
• Study Completion: 2017-07-20
• Status Verified: 2021-06
• Study First Submitted: 2021-06-02
• Study First Submitted QC: 2021-06-02
• Last Update Submitted: 2021-06-02
• Study First Posted: 2021-06-09
• Last Update Posted: 2021-06-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 34

Inclusion Criteria

• People with physical or psychological conditions allow interacting with digital games;
• Elderly over 60 years with mild Alzheimer;
• Seniors over 60 Healthy;
• Healthy Youth;

Exclusion Criteria

• People without physical or psychological conditions allow interacting with digital games;
• Elderly people over 60 years old who have any type of dementia other than Alzheimer, or moderate or severe Alzheimer;

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Healthy elderly people	Virtual Environment	Twelve healthy elderly people. Each participant underwent a pre-test, the intervention with a Virtual Environment, and a post-test.
Elderly people with Alzheimer's in the initial phase	Virtual Environment	Seven elderly people with Alzheimer's in the initial phase. Each participant underwent a pre-test, the intervention with a Virtual Environment, and a post-test.
Healthy young people	Virtual Environment	Fifteen healthy young people. Each participant underwent a pre-test, the intervention with a Virtual Environment, and a post-test.

Primary Outcome Measures

Name	Time	Method
Change on Wechsler Intelligence Scale for Adults (WAIS-III)	Baseline and after 4 weeks	The WAIS-III is an intellectual assessment that aims to analise the measures of the following Factorial Scales and Indexes: Verbal IQ (intelligence quotient), Execution IQ, Total IQ, Verbal Understanding Index, Perceptual Organization Indexes, Operational Memory Indexes and Processing speed index.
Change on Mini Mental State Examination (MMSE)	Baseline and after 4 weeks	The MMSE is a data collection instrument widely used in cases of dementia, it evaluates temporal and spatial orientation, short-term memory (immediate or attention) and skills of evocation, calculation, praxis, visuospatial, communication and language.

Trial Locations

Locations (1)

Terigi Augusto Scardovelli; 🇧🇷 Mogi das Cruzes, São Paulo, Brazil