Internet-Versus Group-Administered Cognitive Behavior Therapy for Panic Disorder

Phase 3

Completed

• Conditions: Panic Disorder
• Interventions: Behavioral: Internet-based cognitive behavior therapy (CBT).; Behavioral: Group CBT

• Registration Number: NCT00845260
• Lead Sponsor: Karolinska Institutet

Brief Summary

Panic Disorder with or without agoraphobia (PD/A) is a common, and unless it is treated, often chronic psychiatric disorder. The are effective pharmacological as well as psychological treatments for PD/A. Because of the lack of availability of the most effective psychological treatment, cognitive behavior therapy (CBT), self-help based CBT treatments have been developed. One of those are Internet-based CBT. The aim of this study is to compare the effectiveness of Internet and group CBT for PD/A in a regular psychiatric setting. 113 patients are consecutively and randomly assigned to either treatment (both lasting 10 weeks). The main outcome measure is the Panic Disorder Severity Scale(PDSS). The study hypothesis is that treatments will show equal effectiveness.

Detailed Description

Not available

Study Timeline

• Study Start: 2004-12
• Primary Completion: 2007-12
• Study Completion: 2007-12
• Status Verified: 2009-02
• Study First Submitted: 2009-02-17
• Study First Submitted QC: 2009-02-17
• Last Update Submitted: 2009-02-17
• Study First Posted: 2009-02-18
• Last Update Posted: 2009-02-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 113

Inclusion Criteria

• Primary Panic Disorder with or without Agoraphobia (PD/A)

Exclusion Criteria

• active substance abuse
• physiological etiology of panic symptoms
• under 18 years of age
• severe depression or suicidal ideation.
• if on drugs for PD, not having had a constant dosage for 2 months
• undergoing other cognitive behavioral treatment

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Internet CBT	Internet-based cognitive behavior therapy (CBT).	Internet-based cognitive behavior therapy (CBT).
Group CBT	Group CBT	Group cognitive behavior therapy (CBT).

Primary Outcome Measures

Name	Time	Method
Panic Disorder Severity Scale (PDSS)	Pre, post at 6-month follow-up

Secondary Outcome Measures

Name	Time	Method
Montgomery-Åsberg Depression Rating Scale (MADRS) Anxiety Sensitivity Index (ASI) Sheehan Disability Scale (SDS)	Pre, post and 6-month follow-up

Trial Locations

Locations (1)

Karolinska Institutet, Department of Clinical Neuroscience, Section of psychiatry, Karolinska Hospital Solna R5; 🇸🇪 Stockholm, Sweden