Efficacy of universal prophylaxis with oral ivermectin for strongyloidiasis in patients administered high-dose corticosteroids
- Conditions
- Strongyloidiasis in patients who administered high-dose corticosteroids.S. stercoralis, strongyloidiasis, ivermectin, prophylaxis, corticosteroids
- Registration Number
- TCTR20221115001
- Lead Sponsor
- /A
- Brief Summary
During follow-up period, S. stercoralis was detected in three patients, two in prophylaxis group and one in definite therapy group which had no statistically significant difference (p-value 1.000). No case of disseminated strongyloidiasis was found. The expense to perform universal prophylaxis strategy was higher than the definite therapy significantly (562.80 vs 254.37 THB/case, p-value .001).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 250
18 years of age or older
Admitted to Khon Kaen University Srinagarind Hospital between January 2015 and June 2019
Received at least 0.5 mg/kg/day of prednisolone or equivalent for at least 14 consecutive days
Had received ivermectin or other drugs for S. stercoralis such as albendazole within 30 days before enrollment
Had evidence of strongyloidiasis but did not receive treatment within seven days
Allergic to ivermectin
Medical records were missing important information
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method umber of S. stercoralis cases detected at 12 months after high dose steroid initiation Fecal examination
- Secondary Outcome Measures
Name Time Method Cost at 12 months after high dose steroid initiation Thai Baht