Assessment of efficacy of intravenous lignocaine infusion for postoperative analgesia and quality of recovery compared to intravenous fentanyl in patients undergoing robotic,laproscopic oncosurgeries
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- 1)To assess postoperative pain using nrs
研究概览
简要总结
After intubation intravenous lignocaine will be started via a dedicated pump via dedicated line,at a dose of 50mcg/kg/min for 1st hr followed by 25mcg/kg/min for next hour followed 12mcg/kg/min for next 22hrs
Pain will be recorded using NRS at 0,4,8,12,20,24 ,36,72hrs
On postoperative days 2 and 3 ,qor-15 questionnaire will be administered to assess quality of recovery
Patients will also be assessed for postoperative nausea and vomiting and bowel recovery
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 70.00 Year(s)（—）
- 性别
- All
入选标准
- •ASA class I and II undergoing robotic and laparoscopic gynaecologic and urologic oncosurgeries under GA 2) Patients who receive intravenous lignocaine infusion as perioperative analgesic.
排除标准
- •Known allergy to lignocaine 2)Intraoperative conversion from minimally invasive to laparotomies 3)Patients with hepatic,renal dysfunction, severe cardiac disease and seizure disorders 4)Inability to comprehend NRS or QoR-15 5)Known allergy to paracetamol and NSAIDs 6)Body weight less than 45 kg.
结局指标
主要结局
1)To assess postoperative pain using nrs
时间窗: 1) for 72hrs postoperatively | 2)2nd and 3rd postoperative day
2)To assess quality of recovery using QoR-15 questionnaire
时间窗: 1) for 72hrs postoperatively | 2)2nd and 3rd postoperative day
3)To assess incidence of PONV and return of bowel function
时间窗: 1) for 72hrs postoperatively | 2)2nd and 3rd postoperative day
次要结局
- 1) To assess analgesic efficacy of iv lignocaine infusion with another analgesic modality-iv fentanyl(2)Time to discharge from hospital)
研究者
Dr Rajasree O
Regional Cancer Centre