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Efficiency of Toothpaste with or without Sodium Lauryl Sulfate on Plaque Index and Gingival Index

Completed
Conditions
Healthyno history of medication use no oral mucosal diseases
Gingival index
Plaque index
Sodium lauryl sulfate
Toothpaste
Registration Number
TCTR20240706002
Lead Sponsor
Srinakharinwirot University
Brief Summary

This study suggested that patients using SLS-free toothpaste were likely to less gingival inflammation than patients using SLS-containing toothpaste. Although the results on the overall effect on oral mucosa are not different between the two toothpastes, SLS-free toothpaste may be useful as an admissible alternative for individuals with oral mucosal lesions

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
30
Inclusion Criteria

This study included thirty healthy participants aged 20-60 years.
All participants provided informed consent.

Exclusion Criteria

Patients using medications that affect oral wound healing, such as corticosteroids
Patients undergoing antibiotic treatment
Pregnant or breastfeeding individuals
Patients with uncontrolled diabetes or other systemic diseases
Smokers
Patients with chronic oral mucosal diseases (e.g., lichen planus, pemphigus vulgaris, pemphigoid)
Individuals already using sodium lauryl sulfate-free toothpaste

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Plaque index (PI), Gingival index (GI) and oral mucosa At first viisit, second visit, third visit and fourth visit Oral examination where baseline measurements were recorded, including PI, GI, and oral mucosa . A randomized, double-blind crossover study to use one of two toothpastes: SLS-containing or SLS-free.
Secondary Outcome Measures
NameTimeMethod
Participants' satisfaction with each type of toothpaste. The fourth visit Satisfaction questionnaire
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