Premature Rupture of Membranes at 34 to 37 Weeks' Gestation :Active vs Conservative Management
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Premature Rupture of Membrane
- Sponsor
- Assiut University
- Enrollment
- 120
- Primary Endpoint
- the percentage of patients with chorioamnionitis
- Last Updated
- 7 years ago
Overview
Brief Summary
Prelabour rupture of membrane is defined as rupture of membranes prior to the onset of labour. Approximately 8% of pregnant women at term experience PROM, but the decision as to how term PROM should be managed clinically remains controversial, and there is wide variation in practice with no clear consensus on what constitutes optimal treatment. Although for the majority of women labour will start spontaneously within 24 hours following term PROM, up to 4%of women will not experience spontaneous onset of labour within seven days.
Investigators
Asmaa Abd El Sattar Ahmed
Principal investigator
Assiut University
Eligibility Criteria
Inclusion Criteria
- •Preterm premature rupture of membranes.
- •Singleton gestation.
- •Pregnant between 34 weeks 0 days to 36 weeks 6 days.
Exclusion Criteria
- •Non cephalic presentation.
- •fetal distress.
- •Labour on admission.
- •Medical or obstetric complications such as(suspected chorioamnionitis ,hypertensive disorders, diabetes mellitus , active genital herpes , placenta previa , infection, meconium stained amniotic fluid ,severe fetal anomalies).
Outcomes
Primary Outcomes
the percentage of patients with chorioamnionitis
Time Frame: 24 hours
Clinical chorioamnionitis is defined in the absence of other causes of hyperpyrexia by a temprature of \>38 C with either uterine tenderness , leucocytosis , maternal or fetal tachycardia , or foul smelling vaginal discharge