Effectiveness of Lee Silverman Voice Treatment (LSVT LOUD) on voice, swallowing and cough function in Parkinson’s Disease: A randomized controlled trial

Not Applicable

Recruiting

• Conditions: Parkinson's disease; Neurological - Parkinson's disease; Physical Medicine / Rehabilitation - Speech therapy

• Registration Number: ACTRN12619001146189
• Lead Sponsor: niversity of Auckland

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2019-08-16
• Last Update Posted: 5 July 2021

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

1)Individuals with PD who meet the inclusion criteria for LSVT LOUD (*see below).
2)Ability to attend the full programme (16 therapy session) and follow up reviews, swallow and cough studies.
3)Ability to complete self-reported questionnaires (PDQ-8, VHI-10, EAT-10, HARQ, and CETI-M) by written completion of the questionnaires or oral report. Carer support can be provided.
*Criteria for Lee Silverman Voice Therapy (LSVT LOUD)
a)Motivated and able to commit to intensive therapy
b)Adequate hearing
c)Adequate cognition and memory
d)Positive results on stimulability testing suggesting likely response to treatment (is the people able to improve loudness and quality? Can they achieve sustained vowel phonation, high and low pitch slide on ‘ah’ and functional phrases?)
e)Socially active and keen to increase participation
f)Otolaryngologist assessment reporting no contraindications to treatment.

Inclusion criteria for healthy control group
1) aged-matched healthy individuals
2) no history of neurological disorders

Exclusion Criteria

1)People with PD without voice dysfunction.
2)Diagnosis of atypical PD.
3)Speech or voice disorder unrelated to PD.
4)Vocal pathology requiring alternative treatment e.g. surgery
5)History of neurosurgical treatment.
6)History of laryngeal surgery or pathology.
7)Previous history of head and neck radiotherapy treatment
8)Co morbidity affecting swallowing ability eg. cerebrovascular accident, neurogenic dysphagia of other aetiology, post-surgical dysphagia, infective dysphagia or dementia, active tumour in larynx/ oesophagus, or Zenker’s diverticulum.
9)Currently pregnant, as evidenced by a positive result on a pregnancy test if the people are within child bearing age (younger than 45 years of age).
10) Presence of a tracheotomy tube or airway obstruction necessitating a tracheotomy tube.
11) Swallowing problem requiring immediate attention.
12) Allergic reaction to the barium contrast agent.
13) People under palliative care.
14) History of speech treatment or LSVT LOUD in the last 2 years.

Study & Design

• Study Type: Interventional
• Study Design: Not specified