Proteomic Analysis of HLA Complex in Solid Cancers: Breast, Ovary, Colon, Rectum, Stomach, and Pancreas

• Conditions: Colorectal Neoplasms; Stomach Neoplasms; Pancreatic Neoplasms; Breast Neoplasms; Ovarian Cancer

• Registration Number: NCT00419627
• Lead Sponsor: Hillel Yaffe Medical Center

Brief Summary

The purpose of this study is to evaluate the presence of proteins in solid tumors which may lead to an immune response

Detailed Description

The main objective of the study is to evaluate which proteins are presented by the HLA complex of solid tumors. Secondary objectives include to evaluate whether an immune response specific to these proteins has actually been provoked and whether there is a similar immune response following recurrence. Real specimens will be evaluated using PCR and mass spectrometry.

Study Timeline

• Status Verified: 2007-01
• Study First Submitted: 2007-01-05
• Study First Submitted QC: 2007-01-05
• Last Update Submitted: 2007-01-05
• Study First Posted: 2007-01-08
• Last Update Posted: 2007-01-08
• Study Start: 2007-02

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 160

Inclusion Criteria

• Patients with adenocarcinoma of breast, colon, rectum, ovary , stomach, pancreas

Exclusion Criteria

• Withdrawal of consent
• Small specimen which does not allow to retrieve tissue without interfering with pathologic evaluation

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

Hillel Yaffe Medical Center; 🇮🇱 Hadera, Israel