Randomized, open and controlled clinical trial to evaluate pain after elective open surgery of the liver and pancreas in patients treated with spinal anesthesia with morphine chloride. On-Q incisional catheters.

Rafael Uña0 个研究点目标入组 60 人开始时间: 2019年7月4日最近更新: 2019年12月10日

适应症

试验速览

暂无简介。

•- Age between 18 and 75 years
•- Hepatic or pancreatic pathology that is going to be operated through open scheduled surgery at the La Paz university hospital (hepatic resection or pancreatic resection with Whipple type reconstruction).
•- Sign informed consent.
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range 60
•F.1.3 Elderly (>=65 years) no
•F.1.3.1 Number of subjects for this age range

•? Patients allergic to local anesthetics.
•? Patients classified as ASA IV.
•? Patients diagnosed with mental retardation (communicative disability with the researcher).
•? Technical impossibility to carry out spinal anesthesia (scoliosis, postsurgical manipulation of the lumbar spine and / or lipoma).
•? Patients previously operated on for open surgery by midline laparotomy.
•? Personal history of chronic use (more than 1 month) of opioids.
•? Patients with chronic renal failure (estimated glomerular filtration rate less than 60 ml / min / 1.73 m2 and / or creatinine greater than 1.5 mg / dl.
•? Patients diagnosed with epilepsy (treated with antiepileptic drugs for more than 1 year).
•? Patients with hepatic impairment (Child B Classification and / or C in the last month).
•? Patients with morbid obesity (BMI greater than 39).
•? Patients diagnosed with obstructive sleep apnea syndrome who are being treated with nocturnal CPAP.
•? Patients who according to the investigator's criteria will not be able to perform the study procedures.

发起方

Rafael Uña