Planned Vaginal Delivery vs Planned Cesarean Delivery in Preterm Twins

Completed

• Conditions: Twin Pregnancy
• Interventions: Other: Survival at discharge; Other: Survival without severe morbidity

• Registration Number: NCT04232436
• Lead Sponsor: University Hospital, Montpellier

Brief Summary

The incidence of twin pregnancies has increased and currently accounts for 1.8% of all deliveries. 47.5% of twins are born prematurely (vs. 6% for singletons) of which 9.9% before 32SA. Caesarean section rates are also higher than for singletons (53.7% vs 19.2%) and 31.8% of caesarean sections are performed before delivery.

The optimal mode of delivery for preterm twins remains controversial. The latest recommendations for clinical practice emphasize that it is not appropriate to recommend one mode of delivery rather than another in the case of twin pregnancies at any term.

In view of all these elements, we wished to carry out a retrospective study at the Montpellier University Hospital in order to compare the neonatal outcome of preterms twins according to their mode of delivery : planned vaginal delivery versus planned cesarean delivery.

Detailed Description

Not available

Study Timeline

• Study Start: 2019-07-01
• Primary Completion: 2019-07-30
• Status Verified: 2020-01
• Study First Submitted: 2020-01-14
• Study First Submitted QC: 2020-01-14
• Study First Posted: 2020-01-18
• Study Completion: 2020-03-01
• Last Update Submitted: 2020-06-04
• Last Update Posted: 2020-06-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 204

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Planned vaginal delivery	Survival without severe morbidity	Planned vaginal delivery
Planned cesarean delivery	Survival without severe morbidity	Planned cesarean delivery
Planned vaginal delivery	Survival at discharge	Planned vaginal delivery
Planned cesarean delivery	Survival at discharge	Planned cesarean delivery

Primary Outcome Measures

Name	Time	Method
survival at discharge and survival	during neonatal hospitalization	survival at discharge and survival without severe morbidity

Secondary Outcome Measures

Name	Time	Method
survival at 2 years of corrected	during the first two years corrected age	survival at 2 years of corrected
age without neurosensory impairment	during the first two years corrected age	age without neurosensory impairment

Trial Locations

Locations (1)

Uhmontpellier; 🇫🇷 Montpellier, France