The Effects of Intensity on Exercise-Induced Hypoalgesia During a Knee Extension Exercise
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Pressure Pain Threshold
研究概览
简要总结
The primary purpose of this study is to to compare immediate changes in pressure pain threshold at the exercising muscle (quadriceps) and a non-exercising muscle (upper trapezius) during low and high weight knee extension exercise. Participants will attend one session that consists of pain sensitivity testing, completion of pain-related psychological questionnaires, and random assignment to one of three interventions: 1) knee extension exercise with a high weight, 2) knee extension exercise with a low weight, or 3) quiet rest.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Pain-free
- •18-60 years old
- •Participant can appropriately perform the knee extension exercise (assessed during screening)
排除标准
- •Non-English speaking
- •Regular use of prescription pain medications
- •Current or history of chronic pain condition
- •Currently taking blood-thinning medication
- •Systemic medical condition known to affect sensation, such as uncontrolled diabetes or neurological conditions
- •Any contraindication to the application of ice, such as: uncontrolled hypertension, cold urticaria, cryoglobulinemia, paroxysmal cold hemoglobinuria, circulatory compromise
- •Known presence of cardiovascular, pulmonary, or metabolic disease
- •Current use of tobacco products
- •Not physically ready to exercise without a medical exam as indicated by the Physical Activity Readiness Questionnaire Plus (PAR-Q+)
- •Surgery, injury, or fracture to the lower back or lower extremity within the past 6 months
研究组 & 干预措施
High Intensity Exercise
Participants will complete a knee extension exercise with weight equivalent to 75% of their 1-repetition maximum for 3 sets of 10 repetitions.
干预措施: Seated knee extension exercise (Other)
Low Intensity Exercise
Participants will complete a knee extension exercise with weight equivalent to 30% of their 1-repetition maximum for 3 sets of 10 repetitions.
干预措施: Seated knee extension exercise (Other)
Quiet Rest
Participants will sit quietly for two minutes, three times.
结局指标
主要结局
Pressure Pain Threshold
时间窗: 1 day
A digital pressure algometer will be applied to the quadriceps and upper trapezius for two trials each. Participants are instructed to say "stop" or "pain" so the stimulus can be terminated "when the sensation first transitions from pressure to pain" (pain threshold). Participants will rate the pain experienced during the threshold testing using a 101-point numeric pain rate scale (NPRS) anchored with 0= no pain to 100= the most intense pain sensation imaginable immediately following each testing time.
次要结局
- Conditioned Pain Modulation(1 day)
研究者
Abigail Wilson
Assistant Professor
University of Central Florida