europrotective effects of L-Carnitine and Fat emulsion in the CVA Ischemic patients
Not Applicable
Completed
- Conditions
- cerebrovascular accident ischemic.Cerebrovascular accident NOS
- Registration Number
- IRCT201510043014N11
- Lead Sponsor
- Vice chancellor for research, Mazandaran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
CVA ischemic MCA inpatient, admitted during first 24 hours after the onset of symptoms, 21-75 years old
Exclusion criteria: less than 21years old and more than 75 years old, hepatic failure( rise hepatic enzymes >5nl, cirrhosis), treatment by valproate, treatment by hemodialysis, sepsis, ARDS, triglyceride > 400, acute pancreatitis plus hyperlipidemia, plt < 70000, signs and symptoms appearance more than 72 hours before admission, CNS infections, seizure, migraine.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method euron specific enolase: NSE. Timepoint: base, 24hr after admission, 48hr after admission, 7th days after admission. Method of measurement: 5 cc serum plasma.;S100B. Timepoint: base, 24hr after admission, 48hr after admission, 7th days after admission. Method of measurement: 5 cc serum plasma.;Lactate dehydrogenase. Timepoint: base, 24hr after admission, 48hr after admission, 7th days after admission. Method of measurement: 5 cc serum plasma.;Pirovate dehydrogenase. Timepoint: base, 24hr after admission, 48hr after admission, 7th days after admission. Method of measurement: 5 cc serum plasma.
- Secondary Outcome Measures
Name Time Method Evaluation neurologic outcomes : Neurologic examination of GCS, cranial nerves, motor nerves, sensory nerves. Timepoint: At admission time and when Discharge from hospital. Method of measurement: Physical examination.