MedPath

Medical Benefit Evaluation of Ambulatory Activity Combining Rehabilitation and Therapeutic Education, Using an Intelligent Electric Bike for the Health, for the Effort Rehabilitation and the Quality of Life Improvement for Patients Suffering of Moderate Fibromyalgia (FIBROVELIS)

Not Applicable
Conditions
Electric Bike
Fibromyalgia
Adapted Physical Activity
Chronic Pain
Therapeutic Education
Interventions
Other: Ambulatory activity combining rehabilitation and therapeutic education, using an Intelligent Electric Bike for the Health.
Registration Number
NCT04318054
Lead Sponsor
University Hospital, Grenoble
Brief Summary

The aim of this study is to decrease the impact of the fibromyalgia on the daily quality of life of the patients suffering of moderate fibromyalgia at 6 months by the practice of an adapted physical activity coupled with therapeutic education workshop.

Detailed Description

Fibromyalgia is chronic pain syndrome expressed as fluctuacting musculotendinous or articular pain and chronic tiredness. Among the non-pharmacological treatments, apart the "psychological" accompanying, the EULAR (European League Against Reumatism) recommends the physical activity in first intention. Thus, physical reconditioning has an important place in fibromyalgia. Aerobic conditioning or reconditioning programs for effort induce for some patients a benefit on quality of life, tiredness and pain. In France, these programmes are mostly carried out in "follow-up and rehabilitation" type care structures.

Outdoor exercise re-training with the Intelligent Electric Bike for Health combined with therapeutic education sessions are proposed in the study. These activities, adapted to each group and patient, can best achieve the objective in an ambulatory format closer to the patient's daily life.

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
56
Inclusion Criteria
  • Patient aged 18 and over
  • Patient available for a following of 18 months
  • Patient available for go to sessions of Intelligent Electric Bike for the Health, 2 half-day by week during 8 weeks in the 2 months following the randomization.
  • confirmed fibromyalgia according to the criteria of the American College of Rhumatology 2010 since at least one year with a stable treatment since at least 3 months.
  • Patients with a score of 39 ≤ FIQ < 59 (moderate fibromyalgia impact)
  • Patient in capacity to pedal on a bike outside.
  • Patient who haven't contraindications at the practice of an moderate physical activity or bike (acute coronary pathology less than 2 years, locomotor problems of the spine or lower limbs incompatible with the bike practice).
  • Weight lower than 125 kg (maximal load for the Intelligent Electric Bike for the Health).
  • Patient having signed the written consent after appropriate information and delivery of the information note.
  • Patient affiliated at the social security or beneficiary of such a scheme
Exclusion Criteria
  • Substantial variation of the therapeutic care in the 3 months previous the inclusion (change of drug class, beginning of physical reconditioning in an unit of follow-up and rehabilitation care, or a cognitive-behavioral technique)
  • Patient with treatement which can deteriorate the attention
  • Patient suffering of a serious chronic desease destabilized (acute coronary pathology and/ or CVA in the last 6 months, serious asthma, serious heart failure, respiratory, lung or kidney failure, progressive inflammatory rheumatic disease...)
  • Women under contraception and with a pregnancy project
  • Patient already includes in a research protocol involving the human person
  • Protected persons

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Deferred intervention groupAmbulatory activity combining rehabilitation and therapeutic education, using an Intelligent Electric Bike for the Health.Deferred intervention group : fibromyalgia patients consulting in Grenoble Alps University Hospital who will practice, one year after the inclusion, an ambulatory activity combining rehabilitation and therapeutic education, using an Intelligent Electric Bike for the Health during 8 weeks (2 times by week).
Immediate intervention groupAmbulatory activity combining rehabilitation and therapeutic education, using an Intelligent Electric Bike for the Health.fibromyalgia patients consulting in Grenoble Alps University Hospital who will practice, in the 2 months following the randomization, an ambulatory activity combining rehabilitation and therapeutic education, using an Intelligent Electric Bike for the Health during 8 weeks (2 times by week).
Primary Outcome Measures
NameTimeMethod
Decrease the impact of the fibromyalgia on the daily quality of life of the patients suffering of moderate fibromyalgia at 6 months by the practice of an adapted physical activity coupled with therapeutic education.6 months

Evolution of the Fibromyalgia Impact Questionnaire (FIQ) at 6 months compared to baseline.

Secondary Outcome Measures
NameTimeMethod
Diminuate the health care consumption of the subjects at 3, 6 and 12 months compared to baseline.3, 6 and 12 months

Decrease of the pharmacological consumption (by therapeutic class : analgesic, antidepressant, antiepileptic, other), medical and paramedical consultation, hospitalization, professional absenteeism, resort to complementary medicine between the inclusion, 3 months, 6 months and 12 months.

Evaluation of the kinetic of the evolution at the inclusion, at short-term (3 months), at medium-term (6 months) and at long-term (12 months) of the FIQ (Fibromyalgia Impact Questionnaire).3, 6 and 12 months

Evolution of the FIQ score between the inclusion, 3 months, 6 months and 12 months.

Improve the global quality of life3, 6 and 12 months

Improvement of the questionnaire EQD-3L between the inclusion, 3 months, 6 months and 12 months.

Evaluate in a global way the disease evolution according to the 4 axis of the EULAR (pain, tiredness, sleep quality, physical activity).3, 6 and 12 months

Evolution of fibromyalgia between the inclusion, 3 months, 6 months and 12 months according to the TSK (Tampa Scale for Kinesiophobia).

Study the impact of the Fibrovelis program on the evolution of the muscular parameter.3 months (second to last trip of the intervention program).

Change from baseline of the muscular parameters record by the Intelligent Electric Bike for the Health during an standardized stress test repeted at the end of after the intervention program.

Evaluate the effect size of the intervention between 12 and 18 months for the diferred intervention group.12 and 18 months

Evolution of the Fibromyalgia Impact Questionnaire (FIQ) and principal secondary outcomes at 18 months compared to 12 months for the diferred intervention group.

In the 2 groups, describe and analyze the effort adaptation in a population suffering of moderate fibromyalgia according the muscular power parameters.3 months

Change from Baseline of the muscular power data.

Improve the mood3, 6 and 12 months

Improvement of the questionnaire HADS between the inclusion, 3 months, 6 months and 12 months.

Improve the perception of the impact of the disease in the relations with close relations3, 6 and 12 months

Evaluation by a close relation of the disease evolution and the relational impact via an VAS between the inclusion, 3 months, 6 months and 12 months.

Compare the percentage of patients who achieve an FIQ<39 at 6 months (threshold defining an fibromyalgia impact weak).6 months

Percentage comparison of the patients who achieve an FIQ\<39 at 6 months.

Improve self-esteem3, 6 and 12 months

Improvement of the score de Rosenberg between the inclusion, 3 months, 6 months and 12 months.

Study the impact of the Fibrovelis program on the evolution of cardio-respiratory physiological efficiency parameter.3 months (second to last trip of the intervention program).

Change from baseline of the cardio-respiratory physiological parameters record by the Intelligent Electric Bike for the Health during an standardized stress test repeted at the end of after the intervention program.

Evaluate the remanence of the long-term effect for the immediate intervention group18 months

Evolution of the Fibromyalgia Impact Questionnaire (FIQ) and principal secondary outcomes at 18 months compared to Baseline for the immediate intervention group.

In the 2 groups, describe and analyze the effort adaptation in a population suffering of moderate fibromyalgia according the cardio respiratory parameters.3 months

Change from Baseline of the cardio respiratory physiological data.

© Copyright 2025. All Rights Reserved by MedPath