To Compare The Efficacy Of Dexmedetomidine V/S Fentanyl In General Anesthesia Technique In Laparoscopic Surgeries
Phase 1
Completed
- Conditions
- Health Condition 1: K352- Acute appendicitis with generalized peritonitis
- Registration Number
- CTRI/2021/07/034882
- Lead Sponsor
- Shilpa Sarang Kore
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 40
Inclusion Criteria
patients undergoing elective laparoscopic surgeries
patients undergoing elective laparoscopic surgeries under general anaesthesia
haemodynamically stable patients with routine investigations within normal limits without any other comorbidities
availability of informed written consent
Exclusion Criteria
Patient refusal
Patients with ASA III or more
Age below 18 years and above 60 years
patients posted for emergency surgeries
patients who are on drugs that can influence hemodynamic and autonomic functions.
patients with predictably difficult airway or difficult intubation
history of cardiac disease and neurologic disease
pregnancy and breast feeding women
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To Compare the efficacy of dexmedetomidine v/s fentanyl based general anaesthesia technique in attenuating neuroendocrine and hemodynamic stress response in laparoscopic surgeries.Timepoint: Every 5 minutes post intubation
- Secondary Outcome Measures
Name Time Method Observe side effects of dexmedetomidine and fentanyl and their managementTimepoint: Anytime after administrating drugs until 24 hours post op;to investigate the effects of dexmedetomidine and fentanyl on modulation of neuroendocrine stress response during elective laparoscopic surgeriesTimepoint: half an hour post intubation, 2 hours post extubation;To study the effects of dexmedetomidine and fentanyl on hemodynamic parameters during perioperative periodTimepoint: Every five minutes post intubation