Amygdala Neurofeedback in Military Aggression: A Pilot Study

Completed

Conditions: aggression regulation problems
Reactive aggression
10021563

Registration Number: NL-OMON48677

Lead Sponsor: niversitair Medisch Centrum Utrecht

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 20

Inclusion Criteria

- Dutch military personnel or veterans
- Age 18-60
- The presence of impulsive aggression problems according to the criteria as described by Coccaro (2012)
- Provide written informed consent

Exclusion Criteria

- Alcohol or drug abuse and/or dependence
- A history of neurological disorders (e.g., Parkinson*s disease, CVA, multiple sclerosis)
- Claustrophobia
- The presence of a pacemaker or other metallic implant that might interfere with MRI acquisition

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study parameters of the proposed study are (i) the tolerability of the<br /><br>training procedure, as measured by a short self-report questionnaire, (ii) the<br /><br>degree to which self-regulation training is successful, measured by statistical<br /><br>analysis of the amygdala signal during feedback runs, and (iii) transfer of the<br /><br>training effects, measured by statistical analysis of the amygdala signal<br /><br>during transfer runs.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>The secundary study parameters of the proposed study are (i) the extent to<br /><br>which the neurofeedback procedure reduces symptoms related to impulsive<br /><br>aggression, as measured by five self-report questionnaries, and (ii) the extent<br /><br>to which functional connectivity between the amygdala and prefrontal cortex is<br /><br>increased as a result of the training procedure, as measured by functional<br /><br>connectivity analysis.</p><br>