Postprandial Response to Almond Consumption in Overweight Hispanic Pregnant Women
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 18
- 试验地点
- 2
- 主要终点
- Change in markers for glucose intolerance.
研究概览
简要总结
Currently, about one third of all women entering pregnancy are obese. The prevalence of metabolic disorders during pregnancy has increased concurrently with the rise in maternal obesity. Although dietary interventions are used routinely to reduce metabolic disease in non-pregnant obese individuals, no specific dietary advice is provided to obese, pregnant women unless they develop gestational diabetes mellitus. In this study, the investigators will specifically assess the effect of replacing dairy fats with almonds in a breakfast meal on the postprandial metabolic response. This cross-over, randomized control trial will examine the postprandial metabolic response to 0 or 2 oz of almonds in standardized test meals in pregnant Hispanic women with prepregnancy BMI between 25 and 40. Hispanics are at higher risk for gestational diabetes and the metabolic syndrome. The investigators hypothesize that consuming almonds in place of dairy fat reduces the glycemic response and improves the postprandial lipid profile in these high-risk women.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Prevention
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 19 Years 至 40 Years(Adult)
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Pregnant Hispanic women
- •Between 30 and 36 weeks gestation
- •Prepregnancy BMI between 25 and 40
排除标准
- •Diagnosis of gestational diabetes mellitus
- •Preexisting diabetes mellitus
- •Renal disease
- •Thyroid disease
- •Cardiovascular disease
- •History of drug abuse
- •Nut allergies
结局指标
主要结局
Change in markers for glucose intolerance.
时间窗: 0, .5, 1, 2, 3, 4, 5 hours following a meal
After consuming the breakfast meal markers for glucose intolerance will be measured at the time points listed
次要结局
- Change in metabolic markers(0, .5, 1, 2, 3, 4, 5 hours following a meal)
