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临床试验/NCT01919476
NCT01919476已完成不适用

Postprandial Response to Almond Consumption in Overweight Hispanic Pregnant Women

UCSF Benioff Children's Hospital Oakland2 个研究点 分布在 1 个国家目标入组 18 人开始时间: 2011年9月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
18
试验地点
2
主要终点
Change in markers for glucose intolerance.

研究概览

简要总结

Currently, about one third of all women entering pregnancy are obese. The prevalence of metabolic disorders during pregnancy has increased concurrently with the rise in maternal obesity. Although dietary interventions are used routinely to reduce metabolic disease in non-pregnant obese individuals, no specific dietary advice is provided to obese, pregnant women unless they develop gestational diabetes mellitus. In this study, the investigators will specifically assess the effect of replacing dairy fats with almonds in a breakfast meal on the postprandial metabolic response. This cross-over, randomized control trial will examine the postprandial metabolic response to 0 or 2 oz of almonds in standardized test meals in pregnant Hispanic women with prepregnancy BMI between 25 and 40. Hispanics are at higher risk for gestational diabetes and the metabolic syndrome. The investigators hypothesize that consuming almonds in place of dairy fat reduces the glycemic response and improves the postprandial lipid profile in these high-risk women.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Prevention
盲法
Single (Investigator)

入排标准

年龄范围
19 Years 至 40 Years(Adult)
性别
Female
接受健康志愿者

入选标准

  • Pregnant Hispanic women
  • Between 30 and 36 weeks gestation
  • Prepregnancy BMI between 25 and 40

排除标准

  • Diagnosis of gestational diabetes mellitus
  • Preexisting diabetes mellitus
  • Renal disease
  • Thyroid disease
  • Cardiovascular disease
  • History of drug abuse
  • Nut allergies

结局指标

主要结局

Change in markers for glucose intolerance.

时间窗: 0, .5, 1, 2, 3, 4, 5 hours following a meal

After consuming the breakfast meal markers for glucose intolerance will be measured at the time points listed

次要结局

  • Change in metabolic markers(0, .5, 1, 2, 3, 4, 5 hours following a meal)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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