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Efficacy and tolerance of Liraglutide for weight loss in obese type 2 diabetic hemodialysis patients

Phase 1
Conditions
obese type 2 diabetic hemodialysis patients
Therapeutic area: Body processes [G] - Metabolic Phenomena [G03]
Registration Number
EUCTR2020-000043-31-FR
Lead Sponsor
Groupe Hospitalier Paris Saint-Joseph
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Authorised-recruitment may be ongoing or finished
Sex
All
Target Recruitment
30
Inclusion Criteria

- Patient aged = 18 and <70
- Patient on hemodialysis for more than 6 months
- Type 2 diabetic patient
- Patient with a BMI> 30 kg / m2 with a Temporary Contraindication for kidney transplant for renal transplant due to overweight by his graft center
- Patient affiliated to a health insurance plan
- French speaking patient
- Patient having given free, informed and written consent
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 10
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range 20

Exclusion Criteria

- Patient with a Temporary Contraindication for kidney transplant for a cause other than overweight
- Patient with personal or family history of thyroid medullary cancer
- Patient with a history of acute or chronic pancreatitis
- Patient who has already had hypersensitivity to liraglutide (or to any other component of the product)
- Patient who has already had a severe digestive intolerance to taking GLP-1 receptor agonists (such as exenatide or lixisenatide)
- Patient already included in an interventional risk research protocol (RIPH1)
- Pregnant or lactating woman
- Patient under guardianship or curatorship
- Patient deprived of liberty

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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