Study to Evaluate Efficacy and Safety of PF-04965842 With or Without Topical Medications in Subjects Aged 12 Years and Older With Moderate to Severe Atopic Dermatitis
- Conditions
- Dermatitis, Atopic
- Interventions
- Registration Number
- NCT03422822
- Lead Sponsor
- Pfizer
- Brief Summary
B7451015 is a Phase 3 study to evaluate Abrocitinib with or without Topical Medications in patients aged 12 years and older who have moderate to severe atopic dermatitis and have completed a qualifying parent study. The efficacy and safety of two dosage strengths of Abrocitinib, 100 mg and 200 mg taken orally once daily, will be evaluated over variable lengths of study participation. The study consists of a 92 week initial treatment period followed by a variable length secondary treatment period during which subjects will receive treatment with open-label abrocitinib until availability of commercial product in their country, or until the sponsor terminates the study in that country.
The B7451015 study also includes a sub-study evaluating whether abrocitinib has any potential effects on adolescent bone with regard to abnormal bone findings in knee MRI. The sub-study will be conducted in selected countries at selected sites. Eligible subjects are those who were 12 to \<18 years of age at the screening visit of the qualifying parent study and who are currently participating in the main B7451015 study. The sub-study will include serial Magnetic Resonance Imaging (MRI) annually and continue until all enrolled subjects are 18 years of age and have been imaged at least once or have discontinued/withdrawn.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ACTIVE_NOT_RECRUITING
- Sex
- All
- Target Recruitment
- 3164
-
Evidence of a personally signed and dated informed consent document indicating that the subject or their parent(s)/legal guardian, if applicable, have been informed of all pertinent aspects of the study.
-
Male or female subjects of 12 years of age or older, at the time of informed consent and meets inclusion criterion for minimum body weight (if applicable) from qualifying Parent study. Adolescent subjects below the age of 18 years old (or country-specific age of majority) will only be enrolled in this study if instructed by the sponsor and approved by the country or regulatory/health authority. If these approvals have not been granted, only subjects aged 18 years (or country-specific age of majority) and older will be enrolled.
-
Willing and able to comply with scheduled visits, treatment plan, laboratory tests and other study procedures.
-
Must have completed the full treatment period of a qualifying Parent study OR must have completed the full rescue treatment period of a qualifying Parent study (if applicable) OR must have completed the full open-label run-in period in B7451014 and did not meet the protocol-specified response criteria at Week 12.
-
Female subjects who are of childbearing potential (which includes all female subjects aged 12 years and older, regardless of whether they have experienced menarche) must ot be intending to become pregnant, currently pregnant, or lactating. The following onditions apply:
- Female subjects of childbearing potential must have a confirmed negative pregnancy test prior to allocation to treatment.
- Female subjects of childbearing potential must agree to use a highly effective method of contraception (as per Section 4.4.1) for the duration of the active treatment period and for at least 28 days after the last dose of investigational product.
For Czech Republic only, 5 b. is revised and 5 c. is added to require:
Female subjects of childbearing potential 15 years of age who are at risk of pregnancy must agree to use a highly effective method of contraception for the duration of the active treatment period and for at least 28 days after the last dose of investigational product.
c. Female subjects less than 15 years of age must not be sexually active, and abstinence per the below definition should be confirmed prior to enrollment. NOTE: Sexual abstinence, defined as completely and persistently refraining from all heterosexual intercourse (including during the entire period of risk associated with the study treatments) may obviate the need for contraception ONLY if this is the preferred and usual lifestyle of the subject.
-
Female subjects of non-childbearing potential must meet at least 1 of the following criteria:
-
Have undergone a documented hysterectomy and/or bilateral oophorectomy;
-
Have medically confirmed ovarian failure; or
-
Achieved postmenopausal status, defined as follows: cessation of regular menses for at least 12 consecutive months with no alternative pathological or physiological cause and have a serum follicle-stimulating hormone (FSH) level confirming the postmenopausal state. All other female subjects (including female subjects with tubal ligations) are considered to be of childbearing potential. 7. Must agree to avoid prolonged exposure to the sun and not to use tanning booths, sun lamps or other ultraviolet light sources during the study.
- Must agree to avoid use of prohibited medications throughout the duration of the study. Exclusion Criteria
- Other acute or chronic medical or psychiatric condition including recent (within the past year) or active suicidal ideation or behavior or laboratory abnormality that may increase the risk associated with study participation or investigational product administration or may interfere with the interpretation of study results and, in the judgment of the investigator, would make the subject inappropriate for entry into this study.
- Currently have active forms of other inflammatory skin diseases, ie, not AD or have evidence of skin conditions (eg, psoriasis, seborrheic dermatitis, Lupus) at the time of Day -1 that would interfere with evaluation of atopic dermatitis or response to treatment.
- Discontinued from treatment (or rescue treatment period/open-label run-in period, if applicable) early in a qualifying Parent study OR triggered a discontinuation criterion at any point during the qualifying Parent study which in the opinion of the investigator, or sponsor, is an ongoing safety concern.
- Ongoing adverse event in the qualifying Parent study which in the opinion of the investigator, or sponsor, is an ongoing safety concern.
- Investigator site staff members directly involved in the conduct of the study and their family members, site staff members otherwise supervised by the investigator, or subjects who are Pfizer employees, including their family members, directly involved in the conduct of the study.
There are also additional separate inclusion and exclusion criteria to assess eligibility specifically for the B7451015 MRI sub-study.
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Abrocitinib 100 mg Abrocitinib 100 mg Abrocitinib 100 mg QD PO Abrocitinib 100 mg Placebo Abrocitinib 100 mg QD PO Abrocitinib 200 mg Abrocitinib 100 mg Abrocitinib 200 mg QD PO Abrocitinib 200 mg Abrocitinib 200 mg Abrocitinib 200 mg QD PO
- Primary Outcome Measures
Name Time Method Treatment emergent adverse events Throughout study regardless of availability of commercial product until at least 2024, or until the sponsor terminates the study; an estimated maximum of 8 years The incidence of treatment emergent adverse events
Serious adverse events and adverse events leading to discontinuation Throughout study regardless of availability of commercial product until at least 2024, or until the sponsor terminates the study; an estimated maximum of 8 years The incidence of serious adverse events and adverse events leading to discontinuation
Change from baseline in clinical laboratory values Throughout study regardless of availability of commercial product until at least 2024, or until the sponsor terminates the study; an estimated maximum of 8 years Change from baseline in clinical laboratory values
Change from baseline in electrocardiogram (ECG) measurements Throughout study regardless of availability of commercial product until at least 2024, or until the sponsor terminates the study; an estimated maximum of 8 years Change from baseline in electrocardiogram (ECG) measurements
Change from baseline in vital signs Throughout study regardless of availability of commercial product until at least 2024, or until the sponsor terminates the study; an estimated maximum of 8 years Change from baseline in vital signs
- Secondary Outcome Measures
Name Time Method Patient Global Assessment (PtGA) Baseline, Week 2, Week 4, Week 12, Week 24, Week 36, Week 48, Week 60, Week 72, Week 84, Week 92 Change from baseline of PtGA at all scheduled time points
Body Surface Area (BSA) affected Throughout study regardless of availability of commercial product until at least 2024, or until the sponsor terminates the study; an estimated maximum of 8 years Change from baseline in the percentage BSA affected at all scheduled time points
Investigator's Global Assessment (IGA) Baseline, Week 2, Week 4, Week 12, Week 24, Week 36, Week 48, Week 60, Week 72, Week 84, Week 92 Response based on the IGA score of clear (0) or almost clear (1) (on a 5 point scale) and a reduction from baseline of \>=2 points at all scheduled time points
Eczema Area and Severity Index (EASI) Throughout study regardless of availability of commercial product until at least 2024, or until the sponsor terminates the study; an estimated maximum of 8 years Response based on greater than or equal to 50%, 75% and 90% improvement from baseline in the EASI total score (EASI50, EASI75, and EASI90) at all scheduled time points
Pruritus Numerical Rating Scale (NRS) Baseline, Week 2, Week 4, Week 12, Week 24, Week 36, Week 48, Week 60, Week 72, Week 84, Week 92 Response based on an improvement greater than or equal to 3 points and greater than or equal to 4 points from baseline in the pruritus NRS at all scheduled time points
Dermatology Life Quality Index (DLQI) or Children's DLQI (CDLQI) Baseline, Week 12, Week 24, Week 36, Week 48, Week 60, Week 72, Week 84, Week 92 Change from baseline in DLQI or CDLQI at all scheduled time points
Patient Oriented Eczema Measure (POEM) Baseline, Week 12, Week 24, Week 36, Week 48, Week 60, Week 72, Week 84, Week 92 Change from baseline in POEM at all scheduled time points
Hospital Anxiety and Depression Scale (HADS) Baseline, Week 12, Week 24, Week 36, Week 48, Week 60, Week 64, Week 72, Week 84, Week 92, Week 96 Change from baseline in HADS at all scheduled time points
EuroQol Quality of Life 5 Dimension 5 Level Scale (EQ-5D-5L) or EuroQol Quality of Life 5 Dimension Youth Scale (EQ-5D-Y) Baseline, Week 24, Week 48, Week 60, Week 72, Week 92 Change from baseline of EQ-5D-5L or EQ-5D-Y at all scheduled time points
Steroid-Free Days Throughout study regardless of availability of commercial product until at least 2024, or until the sponsor terminates the study; an estimated maximum of 8 years Number of steroid-free days will be assessed throughout the duration of the study.
Serum Hs-CRP Levels Throughout study regardless of availability of commercial product until at least 2024, or until the sponsor terminates the study; an estimated maximum of 8 years Serum Hs-CRP levels at all scheduled time points
Change in height standard deviation score (SDS) Throughout study regardless of availability of commercial product until at least 2024, or until the sponsor terminates the study; an estimated maximum of 8 years Change in height standard deviation score (SDS) at all scheduled time points
Proportion of abnormal findings in knee MRI in adolescent subjects exposed to abrocitinib 100mg and 200mg QD Throughout sub-study until all enrolled subjects are 18 years of age and have been imaged at least once or have discontinued or withdrawn; an estimated maximum of 4 years Proportion of abnormal findings in knee MRI in adolescent subjects exposed to abrocitinib 100mg and 200mg QD
Trial Locations
- Locations (528)
Tilda Research Inc.
🇺🇸Irvine, California, United States
Beach Allergy and Asthma Specialty Group, A Medical Corporation
🇺🇸Long Beach, California, United States
Center for Clinical Studies, LTD.LLP
🇺🇸Webster, Texas, United States
Ventavia Research Group
🇺🇸Hurst, Texas, United States
Summit Clinical Research, LLC
🇺🇸Franklin, Virginia, United States
Bugát Pál Kórház, Bőrgyógyászati Szakrendelés
🇭🇺Gyöngyös, Hungary
Trial Pharma Kft.
🇭🇺Püspökladány, Hungary
Borsod-Abaúj-Zemplén Megyei Központi Kórház és Gyermek Gasztroenterológia II. emelet
🇭🇺Miskolc, Hungary
Pecsi Tudomanyegyetem Klinikai Kozpont, Bor-,Nemikortani es Onkodermatologiai Klinika
🇭🇺Pecs, Hungary
Szegedi Tudomanyegyetem Szent-Györgyi Albert
🇭🇺Szeged, Hungary
ALLERGO-DERM BAKOS Kft.
🇭🇺Szolnok, Hungary
Medmare Bt
🇭🇺Veszprem, Hungary
Rabin Medical Center
🇮🇱Petah Tikva, Israel
AOU Policlinico di Modena Struttura complessa di Dermatologia
🇮🇹Modena, MO, Italy
ASST Fatebenefratelli Sacco
🇮🇹Milano, Italy
Istituto Clinico Humanitas IRCSS - UOC di Dermatologia
🇮🇹Milan, Italy
IFO lstituto Dermatologico San Gallicano IRCCS
🇮🇹Roma, Italy
Universita del Sacro Cuore, Policlinico Agostino Gemelli, Istituto Di Dermatologia
🇮🇹Rome, Italy
Kawashima Dermatology Clinic
🇯🇵Ichikawa, Chiba, Japan
Takagi Dermatological Clinic
🇯🇵Obihiro, Hokkaido, Japan
Dermatology Shimizu Clinic
🇯🇵Kobe, Hyogo, Japan
Iidabashi Skin Clinic
🇯🇵Chiyoda-ku, Tokyo, Japan
Fukuwa Clinic
🇯🇵Chuo-ku, Tokyo, Japan
Sumire Dermatology Clinic
🇯🇵Edogawa-ku, Tokyo, Japan
Matsuyama Dermatology Clinic
🇯🇵Nakano-ku, Tokyo, Japan
Sanrui Hifuka
🇯🇵Saitama, Japan
Hallym University Kangnam Sacred Heart Hospital
🇰🇷Seoul, Korea, Republic of
Riga 1st Hospital, Clinic of Dermatology and STD
🇱🇻Riga, Latvia
Aesthetic dermatology clinic of Prof. J. Kisis
🇱🇻Riga, Latvia
Health Centre 4 Ltd. Diagnostics Centre
🇱🇻Riga, Latvia
Childrens Clinical University Hospital State SLLC
🇱🇻Riga, Latvia
Health and Aesthetics Ltd
🇱🇻Riga, Latvia
Health Centre 4 Ltd, Dermatology Clinics
🇱🇻Riga, Latvia
Outpatient Clinic Of Ventspils
🇱🇻Ventspils, Latvia
Hospital Infantil de Mexico Federico Gomez
🇲🇽Del. Cuauhtemoc, Ciudad DE Mexico, Mexico
Clinical Research Institute S.C.
🇲🇽Saltillo, Coahuila, Mexico
Centro de Dermatologia de Monterrey
🇲🇽Monterrey, Nuevo LEON, Mexico
Centro Multidisciplinario para el Desarrollo Especializado de la Investigacion Clinica en Yucatan
🇲🇽Merida, Yucatan, Mexico
JM Research SC
🇲🇽Cuernavaca, Morelos, Mexico
Centro de Investigacion Integral MEDIVEST, S.C.
🇲🇽Chihuahua, Mexico
Servicios Hospitalarios de Mexico S.A. de C.V. (Hospital Ángeles Chihuahua)
🇲🇽Chihuahua, Mexico
Phylasis Clinicas Research S. de R.L. de C.V.
🇲🇽Cuautitlan Izcalli, Mexico
Hospital de Jesus, I.A.P.
🇲🇽Mexico City, Mexico
Cryptex Investigación Clínica, S.A. de C.V.
🇲🇽Mexico City, Mexico
Arke Estudios Clinicos Sa De Cv
🇲🇽Mexico city, Mexico
Trials in Medicine S.C.
🇲🇽Mexico City, Mexico
Eukarya Pharmasite S.C.
🇲🇽Monterrey, Mexico
SMIQ, S. de R. L. de C.V.
🇲🇽Queretaro, Mexico
Sociedad de Metabolismo y Corazon S.C.
🇲🇽Veracruz, Mexico
Universitair Medisch Centrum (UMC) Utrecht
🇳🇱Utrecht, Netherlands
DERMAPOLIS Medical Dermatology Center dr n. med. Edyta Gębska
🇵🇱Chorzow, Poland
Uniwersyteckie Centrum Kliniczne Klinika Dermatologii, Wenerologii i Alergologii
🇵🇱Gdansk, Poland
The Centre for Dermatology
🇨🇦Richmond Hill, Ontario, Canada
York Dermatology Clinic and Research Centre
🇨🇦Richmond Hill, Ontario, Canada
Medicor Research Inc
🇨🇦Sudbury, Ontario, Canada
Sudbury Skin Clinique
🇨🇦Sudbury, Ontario, Canada
Innovaderm Research Inc.
🇨🇦Montreal, Quebec, Canada
Diex Research Sherbrooke Inc.
🇨🇦Sherbrooke, Quebec, Canada
K.Papp Clinical Research Inc.
🇨🇦Waterloo, Ontario, Canada
Wojskowy Instytut Medyczny, Klinika Dermatologiczna
🇵🇱Warszawa, Poland
EMC Instytut Medyczny S.A. Przychodnia przy ul. Lowieckiej
🇵🇱Wroclaw, Poland
Synexus Polska Sp. z o.o. Oddzial we Wroclawiu
🇵🇱Wroclaw, Poland
Lukasz Matusiak "4Health"
🇵🇱Wroclaw, Poland
Centrum Medyczne Oporow
🇵🇱Wroclaw, Poland
Kliniczny Oddzial Chorob Wewnetrznych, Dermatologii i Alergologii
🇵🇱Zabrze, Poland
NRC Institute of Immunology FMBA of Russia
🇷🇺Moscow, Russian Federation
SBI RR "Skin and Venereal Dispensary"
🇷🇺Rostov-on-Don, Russian Federation
SBI RR "Regional Clinical Skin and Veneral Dispensary"
🇷🇺Ryazan, Russian Federation
Limited Liability Company "Sanavita"
🇷🇺Saint Petersburg, Russian Federation
Vitiligo center
🇷🇺Saint-Petersburg, Russian Federation
RSBIH "Smolensk Regional Clinical Hospital"
🇷🇺Smolensk, Russian Federation
Clinical Centre Nis
🇷🇸Nis, Serbia
General Hospital Pancevo
🇷🇸Pancevo, Serbia
SKINKLINIK s.r.o.
🇸🇰Bratislava- Mestská Časť Nové Mesto, Slovakia
Narodny ustav detskych chorob
🇸🇰Bratislava, Slovakia
BeneDerma s.r.o.
🇸🇰Bratislava, Slovakia
Derma therapy spol. s.r.o, Dermatovenerologicka ambulancia
🇸🇰Bratislava, Slovakia
Derma-beauty, s.r.o., Dermatovenerologicka ambulancia
🇸🇰Nitra, Slovakia
"DCC Aleksandrovska" EOOD
🇧🇬Sofia, Bulgaria
"DCC Mladost-M Varna" OOD
🇧🇬Varna, Bulgaria
Dermatology Research Institute
🇨🇦Calgary, Alberta, Canada
Beacon Dermatology
🇨🇦Calgary, Alberta, Canada
Stratica Medical
🇨🇦Edmonton, Alberta, Canada
Alberta Dermasurgery Centre
🇨🇦Edmonton, Alberta, Canada
Pacific Dermaesthetics Inc.
🇨🇦Vancouver, British Columbia, Canada
Winnipeg Clinic
🇨🇦Winnipeg, Manitoba, Canada
Wiseman Dermatology Research Inc.
🇨🇦Winnipeg, Manitoba, Canada
CCA Medical Research
🇨🇦Ajax, Ontario, Canada
SimcoDerm Medical and Surgical Dermatology Center
🇨🇦Barrie, Ontario, Canada
Derm Effects
🇨🇦London, Ontario, Canada
Lynderm Research Inc.
🇨🇦Markham, Ontario, Canada
North Bay Dermatology Centre
🇨🇦North Bay, Ontario, Canada
The Centre for Clinical Trials
🇨🇦Oakville, Ontario, Canada
Oshawa Clinic Dermatology Trials
🇨🇦Oshawa, Ontario, Canada
Dermatology Ottawa Research Centre
🇨🇦Ottawa, Ontario, Canada
SKiN Centre for Dermatology
🇨🇦Peterborough, Ontario, Canada
PMG Research of Winston-Salem, LLC
🇺🇸Winston-Salem, North Carolina, United States
Winston-Salem Dermatology and Surgery Center, PLLC
🇺🇸Winston-Salem, North Carolina, United States
The Ohio State University Wexner Medical Center
🇺🇸Columbus, Ohio, United States
The Ohio State University Dermatology East
🇺🇸Gahanna, Ohio, United States
Lynn Health Science Institute
🇺🇸Oklahoma City, Oklahoma, United States
Newton Clinical Research
🇺🇸Oklahoma City, Oklahoma, United States
Vital Prospects Clinical Research Institute, P.C.
🇺🇸Tulsa, Oklahoma, United States
Portland Clinical Research dba Columbia Asthma & Allergy Clinic
🇺🇸Clackamas, Oregon, United States
Velocity Clinical Research, Medford
🇺🇸Medford, Oregon, United States
Oregon Medical Research Center
🇺🇸Portland, Oregon, United States
Shanghai Dermatology Hospital
🇨🇳Shanghai, China
Kozni ambulance Kutna Hora, s.r.o
🇨🇿Kutná Hora, Czechia
Dermamedica S.R.O.
🇨🇿Nachod, Czechia
Fakultni Nemocnice Ostrava, Kozni oddeleni
🇨🇿Ostrava - Poruba, Czechia
Dr. Rachel Asiniwasis, Medical Professional Corp.
🇨🇦Regina, Saskatchewan, Canada
Centre de Recherche Dermatologique du Quebec metropolitain (CRDQ)
🇨🇦Quebec, Canada
Clinica Dermacross S.A.
🇨🇱Santiago, Region Metropolitana, Chile
Centro Internacional de Estudios Clinicos - CIEC
🇨🇱Santiago, Region Metropolitana, Chile
Hospital Clinico Universidad de Chile
🇨🇱Santiago, Región Metropolitana, Chile
Beijing Friendship Hospital, Capital Medical University
🇨🇳Beijing, Beijing, China
Nemocnice Pardubickeho kraje, a.s., Pardubicka nemocnice
🇨🇿Pardubice, Czechia
The First Affiliated Hospital, Sun Yat-sen University
🇨🇳Guangzhou, Guangdong, China
The University of Hong Kong - Shenzhen Hospital
🇨🇳Shenzhen, Guangdong, China
The second Xiangya Hospital,Central South University
🇨🇳Changsha, Hunan, China
First Affiliated Hospital of Kunming Medical University
🇨🇳Kunming, Yunnan, China
Nemocnica Kosice-Saca, a.s., 1. sukromna nemocnica, Kozna ambulancia
🇸🇰Kosice-Saca, Slovakia
Licca Clinical Research Institute
🇩🇪Augsburg, Germany
Fachklinik Bad Bentheim
🇩🇪Bad Bentheim, Germany
Charite-Universitaetsmedizin Berlin
🇩🇪Berlin, Germany
Hautzentrum Friedrichshain Studien
🇩🇪Berlin, Germany
Rothhaar Studien GmbH
🇩🇪Berlin, Germany
ISA GmbH
🇩🇪Berlin, Germany
Klinikum Bielefeld Rosenhoehe
🇩🇪Bielefeld, Germany
Universitaetsklinikum Bonn
🇩🇪Bonn, Germany
Klinische Forschung Dresden GmbH
🇩🇪Dresden, Germany
Universitaetsklinikum Carl Gustav Carus der Technischen Universitaet Dresden
🇩🇪Dresden, Germany
IKF Pneumologie GmbH & Co KG; Institut für klinische Forschung
🇩🇪Frankfurt, Germany
SRH Wald-Klinikum Gera GmbH
🇩🇪Gera, Germany
Klinische Forschung Hamburg GmbH
🇩🇪Hamburg, Germany
MENSINGDERMA research GmbH
🇩🇪Hamburg, Germany
Medizinische Hochschule Hannover
🇩🇪Hannover, Germany
Universitaetsklinikum Schleswig-Holstein, Campus Kiel
🇩🇪Kiel, Germany
Praxis Dr. med. Beate Schwarz
🇩🇪Langenau, Germany
Velocity Clinical Research Germany GmbH
🇩🇪Leipzig, Germany
Universitaetsklinikum Schleswig-Holstein, Campus Luebeck
🇩🇪Luebeck, Germany
Dermatologische Gemeinschaftspraxis
🇩🇪Mahlow, Germany
Dermatologische Gemeinschaftspraxis Dres. Quist
🇩🇪Mainz, Germany
Universitätsklinikum Marburg
🇩🇪Marburg, Germany
University of Muenster
🇩🇪Muenster, Germany
Ludwig-Maximilians-University Munich
🇩🇪Munich, Germany
Klinische Forschung Schwerin GmbH
🇩🇪Schwerin, Germany
Hautaerztliche Gemeinschaftspraxis Dres. Leitz und Kollegen
🇩🇪Stuttgart, Germany
Clinexpert Kft.
🇭🇺Budapest, Hungary
SE AOK Bor, Nemikortani es Boronkologiai Klinika
🇭🇺Budapest, Hungary
Bp. Főváros XIX. Kerület Önkormányzat Kispesti Eü. Intézete
🇭🇺Budapest, Hungary
Debreceni Egyetem Klinikai Kozpont
🇭🇺Debrecen, Hungary
CRU Hungary Kft.
🇭🇺Encs, Hungary
Synexus Magyarország Egészségügyi Szolgáltató Kft. Synexus Gyula DRS
🇭🇺Gyula, Hungary
Care Clinic Centrum Medyczne
🇵🇱Katowice, Poland
Pro Familia Altera Sp. z o.o.
🇵🇱Katowice, Poland
Centrum Nowoczesnych Terapii "DOBRY LEKARZ" sp. z o.o.
🇵🇱Krakow, Poland
Centrum Badan Klinicznych JCI
🇵🇱Krakow, Poland
NZOZ "DERMED" Centrum Medyczne Sp. z o.o. - Oddzial w Lodzi
🇵🇱Lodz, Poland
Centrum Medyczne Plejady
🇵🇱Krakow, Poland
Krakowskie Centrum Medyczne Sp. z o.o.
🇵🇱Krakow, Poland
Osrodek badan klinicznych AppleTree Clinics
🇵🇱Lodz, Poland
Dermoklinika-Centrum Medyczne s.c. M. Kierstan, J. Narbutt, A. Lesiak
🇵🇱Lodz, Poland
KO-MED Centra Kliniczne Lublin II
🇵🇱Lublin, Poland
Clinical Research Center Sp. z o.o. MEDIC-R Sp. k.
🇵🇱Poznan, Poland
NZOZ "Med-Laser" Borzecki Spolka Jawna
🇵🇱Lublin, Poland
Dermedic Jacek Zdybski
🇵🇱Ostrowiec Swietokrzyski, Poland
Synexus Polska Sp. z o.o. Oddzial w Poznaniu
🇵🇱Poznan, Poland
REUMATIKA - "Centrum Reumatologii" NZOZ 2
🇵🇱Warszawa, Poland
Synexus Polska Sp. z o.o. Oddzial w Warszawie
🇵🇱Warszawa, Poland
Gabinety Lekarskie Rivermed
🇵🇱Poznan, Poland
LIFT-MED Spolka Akcyjna
🇵🇱Rybnik, Poland
Kliniczny Szpital Wojewodzki nr 1 im. F. Chopina, Klinika Dermatologii
🇵🇱Rzeszow, Poland
EMED Centrum Uslug Medycznych Ewa Smialek
🇵🇱Rzeszow, Poland
Andrzej Krolicki, Tomasz Kochanowski "Laser Clinic" S.C.
🇵🇱Szczecin, Poland
Alergo-Med Specjalistyczna Przychodnia Lekarska Sp. z o.o.
🇵🇱Tarnow, Poland
Twoja Przychodnia Szczecinskie Centrum Medyczne
🇵🇱Szczecin, Poland
MICS Centrum Medyczne Warszawa
🇵🇱Warszawa, Poland
Centrum Medyczne AMED
🇵🇱Warszawa, Poland
MTZ Clinical Research Powered by Pratia
🇵🇱Warszawa, Poland
Klinika Ambroziak Sp. z o.o.
🇵🇱Warszawa, Poland
Bexley Dermatology Research
🇺🇸Bexley, Ohio, United States
Emmaus Research Center, Inc.
🇺🇸Anaheim, California, United States
California Dermatology & Clinical Research Institute
🇺🇸Encinitas, California, United States
First OC Dermatology Research Inc
🇺🇸Fountain Valley, California, United States
Marvel Research, LLC
🇺🇸Huntington Beach, California, United States
Keck School of Medicine of University of Southern California
🇺🇸Los Angeles, California, United States
University of Southern California
🇺🇸Los Angeles, California, United States
Clinical Trials Solutions
🇺🇸Miami, Florida, United States
Global Health Clinical Trials Corp
🇺🇸Miami, Florida, United States
Baumann Cosmetic and Research Institute
🇺🇸Miami, Florida, United States
Skin Specialists PC
🇺🇸Omaha, Nebraska, United States
UR Dermatology at College Town
🇺🇸Rochester, New York, United States
Investigational Drug Service
🇺🇸Rochester, New York, United States
Cary Dermatology Center, PA
🇺🇸Cary, North Carolina, United States
M3-Wake Research, Inc.
🇺🇸Raleigh, North Carolina, United States
Carolina Research Center, Inc.
🇺🇸Shelby, North Carolina, United States
PMG Research of Wilmington LLC
🇺🇸Wilmington, North Carolina, United States
PMG Research of Wilmington, LLC
🇺🇸Wilmington, North Carolina, United States
Accellacare - Cary
🇺🇸Cary, North Carolina, United States
Arlington Research Center, Inc.
🇺🇸Arlington, Texas, United States
Center for Clinical Studies, LTD. LLP
🇺🇸Houston, Texas, United States
Austin Institute for Clinical Research, Inc.
🇺🇸Pflugerville, Texas, United States
Texas Dermatology and Laser Specialists
🇺🇸San Antonio, Texas, United States
Dermatology Clinical Research Center of San Antonio
🇺🇸San Antonio, Texas, United States
Virginia Clinical Research, Inc
🇺🇸Norfolk, Virginia, United States
Fort Norfolk Diagnostic Center
🇺🇸Norfolk, Virginia, United States
Pace Dermatology Associates
🇺🇸Tacoma, Washington, United States
Principle Research Solutions
🇺🇸Spokane, Washington, United States
MultiCare Allenmore Hospital
🇺🇸Tacoma, Washington, United States
CARE Clinic Ltd
🇨🇦Red Deer, Alberta, Canada
Dr. Chih-ho Hong Medical Inc
🇨🇦Surrey, British Columbia, Canada
Dermatology Hospital of Jiangxi Province
🇨🇳Nanchang, Jiangxi, China
Dermatology Department, Shanghai Changzheng Hospital
🇨🇳Shanghai, China
Lekarna Fakultni Nemocnice Ostrava
🇨🇿Ostrava - Poruba, Czechia
CCR Ostrava, s.r.o.
🇨🇿Ostrava, Czechia
Lekarna Rezidence Nova Karolina
🇨🇿Ostrava, Czechia
Apavar Lekarna
🇨🇿Ostrava, Czechia
BENU Lekarna
🇨🇿Pardubice, Czechia
PRATIA Pardubice a.s.
🇨🇿Pardubice, Czechia
Lekarna, Nemocnice Pardubickeho kraje, a.s. , Pardubicka nemocnice
🇨🇿Pardubice, Czechia
Lekarna Pod Platany (Pharmacy)
🇨🇿Praha 10, Czechia
Prof. MUDr.Petr Arenberger, DrSc. MBA
🇨🇿Praha 1, Czechia
PRATIA Prague s.r.o.
🇨🇿Praha 3, Czechia
Lekarna U Spasitele
🇨🇿Praha, Czechia
Dermatovenerologicka ambulance
🇨🇿Svitavy, Czechia
Lekarna na Hranicni (Pharmacy)
🇨🇿Svitavy, Czechia
Krajska zdravotni a.s., Masarykova nemocnice o.z.
🇨🇿Usti nad Labem, Czechia
Lekarna Masarykovy nemocnice v Usti nad Labem, o.z.
🇨🇿Usti nad Labem, Czechia
Terveystalo Tampere
🇫🇮Tampere, Finland
Mehiläinen Neo
🇫🇮Turku, Finland
Turun yliopistollinen keskussairaala
🇫🇮Turku, Finland
Dermazentrum Augsburg
🇩🇪Augsburg, Germany
Neutrum Lekarze M. Hlebowicz i Partnerzy Spolka Partnerska
🇵🇱Gdansk, Poland
Szpital Sw. Wojciecha
🇵🇱Gdansk, Poland
Synexus Polska Sp. z o.o. Oddzial w Gdyni
🇵🇱Gdynia, Poland
MULTIKLINIKA Salute Sp. z o.o.
🇵🇱Katowice, Poland
MCBK
🇵🇱Grodzisk Mazowiecki, Poland
Centrum Medyczne Angelius Provita
🇵🇱Katowice, Poland
Gabinet Dermatologiczny Beata Krecisz
🇵🇱Kielce, Poland
Malopolskie Centrum Kliniczne
🇵🇱Krakow, Poland
AWP Klinika Dermatologii Pod Fortem Anna Wojas-Pelc
🇵🇱Krakow, Poland
Centrum Medyczne Promed
🇵🇱Krakow, Poland
Prywatna Praktyka Lekarska - Adam Smialowski INTERMED KSAWEROW
🇵🇱Ksawerow, Poland
Centrum Terapii Wspolczesnej J.M. Jasnorzewska Spolka Komandytowo-Akcyjna
🇵🇱Lodz, Poland
Synexus Polska Sp. z o.o. Oddzial w Katowicach
🇵🇱Katowice, Poland
Silmedic Sp. z o.o., Oddzial w Katowicach
🇵🇱Katowice, Poland
Fakultna nemocnica s poliklinikou Nove Zamky, Dermatovenerologicka klinika
🇸🇰Nove Zamky, Slovakia
SANARE spol.s.r.o.
🇸🇰Svidnik, Slovakia
Hospital Universitari Germans Trias i Pujol
🇪🇸Badalona, Barcelona, Spain
Hospital General Universitario de Alicante
🇪🇸Alicante, Spain
Hospital Universitario Reina Sofia
🇪🇸Cordoba, Spain
Hospital Universitario de La Princesa
🇪🇸Madrid, Spain
Hospital General Universitario Gregorio Maranon
🇪🇸Madrid, Spain
Hospital del Nino Jesus
🇪🇸Madrid, Spain
Hospital Universitario 12 de octubre
🇪🇸Madrid, Spain
Hospital Universitario La Paz
🇪🇸Madrid, Spain
Centro de Especialidades Mollabao (Area Sanitaria de Pontevedra e O Salnes)
🇪🇸Pontevedra, Spain
Hospital de Montecelo
🇪🇸Pontevedra, Spain
Hospital Universitario Virgen de la Macarena
🇪🇸Sevilla, Spain
MAC Clinical Research
🇬🇧Cannock, United Kingdom
University Hospital Bristol NHS Foundation Trust
🇬🇧Bristol, United Kingdom
Accellacare Warwickshire
🇬🇧Coventry, United Kingdom
West Glasgow Ambulatory Care Hospital
🇬🇧Glasgow, United Kingdom
Guy's Hospital-Guy's and St Thomas NHS Foundation Trust
🇬🇧London, United Kingdom
MAC Clinical Research Ltd
🇬🇧Manchester, United Kingdom
Accellacare South London
🇬🇧Orpington, United Kingdom
La Salud Research Clinic, Inc.
🇺🇸Miami, Florida, United States
North York Research Inc.
🇨🇦Toronto, Ontario, Canada
Toronto Research Centre
🇨🇦Toronto, Ontario, Canada
Research Toronto
🇨🇦Toronto, Ontario, Canada
AvantDerm
🇨🇦Toronto, Ontario, Canada
Manna Research Inc.(Toronto)
🇨🇦Toronto, Ontario, Canada
XLR8 Medical Research Inc.
🇨🇦Windsor, Ontario, Canada
Clinique de Radiologie du Saguenay Enr.
🇨🇦Chicoutimi, Quebec, Canada
"DCC Fokus-5-Medical Establishment for OutpatientCare"EOOD
🇧🇬Sofia, Bulgaria
ACIBADEM City Clinic Diagnostic-Consultative Center EOOD
🇧🇬Sofia, Bulgaria
Medical Center Synexus Sofia EOOD-branch Stara Zagora
🇧🇬Stara Zagora, Bulgaria
"ACIBADEM City Clinic Medical Center Varna" EOOD
🇧🇬Varna, Bulgaria
Hospital de Clinicas de Porto Alegre (HCPA)
🇧🇷Porto Alegre, RS, Brazil
"Acibadem City Clinic MHAT Tokuda" EAD
🇧🇬Sofia, Bulgaria
Total Skin and Beauty Dermatology Center, PC
🇺🇸Birmingham, Alabama, United States
Clinical Research Center of Alabama, LLC
🇺🇸Birmingham, Alabama, United States
University of Alabama at Birmingham - Dermatology Research Clinic
🇺🇸Birmingham, Alabama, United States
University of Alabama at Birmingham Hospital Outreach Lab
🇺🇸Birmingham, Alabama, United States
The University of Alabama at Birmingham, Department of Dermatology
🇺🇸Birmingham, Alabama, United States
University of California San Diego Dermatology
🇺🇸San Diego, California, United States
Wallace Medical Group, Inc
🇺🇸Los Angeles, California, United States
Allergy & Asthma Associates of Southern California dba Southern California Research
🇺🇸Mission Viejo, California, United States
Dermatology Specialists, Inc.
🇺🇸Oceanside, California, United States
Peninsula Headlands LLC
🇺🇸Rolling Hills Estates, California, United States
UC Davis Health
🇺🇸Sacramento, California, United States
MedDerm Associates
🇺🇸San Diego, California, United States
Synergy Dermatology
🇺🇸San Francisco, California, United States
San Luis Dermatology and Laser Clinic
🇺🇸San Luis Obispo, California, United States
Southern California Dermatology, Inc.
🇺🇸Santa Ana, California, United States
Wolverine Clinical Trials, Llc
🇺🇸Santa Ana, California, United States
Mosaic Dermatology
🇺🇸Santa Monica, California, United States
Clinical Science Institute
🇺🇸Santa Monica, California, United States
Asthma and Allergy Associates, PC
🇺🇸Colorado Springs, Colorado, United States
Colorado Springs Dermatology Clinic, PC
🇺🇸Colorado Springs, Colorado, United States
Skin Care Research
🇺🇸Boca Raton, Florida, United States
Renaissance Research and Medical Group, Inc
🇺🇸Cape Coral, Florida, United States
Florida Academic Centers Research and Education, LLC
🇺🇸Coral Gables, Florida, United States
Skin Research Institute
🇺🇸Coral Gables, Florida, United States
Moonshine Research Center, Inc.
🇺🇸Doral, Florida, United States
Homestead Research Institute
🇺🇸Homestead, Florida, United States
Clinical Neuroscience Solutions, Inc.
🇺🇸Memphis, Tennessee, United States
Solutions Through Advanced Research, Inc.
🇺🇸Jacksonville, Florida, United States
C & R Research Services USA, Inc
🇺🇸Kendall, Florida, United States
Savin Medical Group LLC
🇺🇸Miami Lakes, Florida, United States
Wellness Clinical Research, LLC
🇺🇸Miami Lakes, Florida, United States
Suncoast Research Associates
🇺🇸Miami, Florida, United States
Nicklaus Children's Hospital
🇺🇸Miami, Florida, United States
Ciocca Dermatology, PA
🇺🇸Miami, Florida, United States
Miami Dermatology & Laser Research, LLC
🇺🇸Miami, Florida, United States
Park Avenue Dermatology
🇺🇸Orange Park, Florida, United States
Outpatient Services Center - AdventHealth Orlando
🇺🇸Orlando, Florida, United States
ASR, LLC
🇺🇸Nampa, Idaho, United States
Ds Research
🇺🇸Clarksville, Indiana, United States
The Indiana Clinical Trials Center
🇺🇸Plainfield, Indiana, United States
Kansas City Dermatology, PA
🇺🇸Overland Park, Kansas, United States
South Miami Medical & Research Group, Inc.
🇺🇸Miami, Florida, United States
INTERMED Medical Research Center, Inc
🇺🇸Miami, Florida, United States
AdventHealth Orlando
🇺🇸Orlando, Florida, United States
AdventHealth Pediatric Dermatology Orlando
🇺🇸Orlando, Florida, United States
Advent Health Orlando - Investigational Drug Services
🇺🇸Orlando, Florida, United States
Pediatric Outpatient Procedures and Sedation
🇺🇸Orlando, Florida, United States
Accel Research Sites - Nona Pediatric Center
🇺🇸Orlando, Florida, United States
Olympian Clinical Research
🇺🇸Tampa, Florida, United States
Clinical Research Trials of Florida, Inc.
🇺🇸Tampa, Florida, United States
Clinical Research Trials of Florida
🇺🇸Tampa, Florida, United States
ForCare Clinical Research
🇺🇸Tampa, Florida, United States
University of South Florida; Asthma, Allergy and Immunology Clinical Research Unit
🇺🇸Tampa, Florida, United States
Integrated Clinical Research
🇺🇸West Palm Beach, Florida, United States
Columbus Regional Research Institute
🇺🇸Columbus, Georgia, United States
IACT Health
🇺🇸Columbus, Georgia, United States
One Health Research Clinic Atlanta, LLC
🇺🇸Johns Creek, Georgia, United States
Dermatologic Surgery Specialists, PC
🇺🇸Macon, Georgia, United States
Meridian Clinical Research
🇺🇸Savannah, Georgia, United States
Midwest Allergy Sinus Asthma, SC
🇺🇸Normal, Illinois, United States
NorthShore University HealthSystem - Dermatology
🇺🇸Skokie, Illinois, United States
NorthShore University HealthSystem Dermatology Clinical Trials Unit
🇺🇸Skokie, Illinois, United States
Dundee Dermatology
🇺🇸West Dundee, Illinois, United States
Dawes Fretzin Dermatology Group, LLC
🇺🇸Indianapolis, Indiana, United States
The South Bend Clinic Center for Research
🇺🇸South Bend, Indiana, United States
Skin Sciences, PLLC
🇺🇸Louisville, Kentucky, United States
Qualmedica Research, LLC.
🇺🇸Owensboro, Kentucky, United States
Onyx Clinical Research
🇺🇸Flint, Michigan, United States
Owensboro Dermatology Associates
🇺🇸Owensboro, Kentucky, United States
Meridian Clinical Research, LLC
🇺🇸Baton Rouge, Louisiana, United States
Avant Research Associates LLC
🇺🇸Crowley, Louisiana, United States
Tulane University Health Sciences Center
🇺🇸New Orleans, Louisiana, United States
Institute for Asthma and Allergy
🇺🇸Chevy Chase, Maryland, United States
DermAssociates, LLC
🇺🇸Rockville, Maryland, United States
Chesapeake Clinical Research, Inc.
🇺🇸White Marsh, Maryland, United States
Tufts Medical Center
🇺🇸Boston, Massachusetts, United States
Massachusetts General Hospital - Clinical Unit for Research Trials in Skin (CURTIS)
🇺🇸Boston, Massachusetts, United States
MetroBoston Clinical Partners, LLC
🇺🇸Brighton, Massachusetts, United States
Clarkston Skin Research
🇺🇸Clarkston, Michigan, United States
Henry Ford Medical Center, New Center One
🇺🇸Detroit, Michigan, United States
Revival Research Institute, LLC
🇺🇸Troy, Michigan, United States
Somerset Skin Centre
🇺🇸Troy, Michigan, United States
Henry Ford Medical Center - Farmington Road
🇺🇸West Bloomfield, Michigan, United States
Clinical Research Institute, Inc.
🇺🇸Minneapolis, Minnesota, United States
Mayo Clinic
🇺🇸Rochester, Minnesota, United States
MediSearch Clinical Trials
🇺🇸Saint Joseph, Missouri, United States
Saint Louis University Dermatology
🇺🇸Saint Louis, Missouri, United States
Medication Management, LLC
🇺🇸Greensboro, North Carolina, United States
Hamzavi Dermatology
🇺🇸Fort Gratiot, Michigan, United States
Forest Hills Dermatology Group
🇺🇸Kew Gardens, New York, United States
Icahn School of Medicine at Mount Sinai
🇺🇸New York, New York, United States
Children's Hospital of Wisconsin Investigational Drug Service
🇺🇸Milwaukee, Wisconsin, United States
Veracity Clinical Research Pty Ltd
🇦🇺Woolloongabba, Queensland, Australia
North Eastern Health Specialists
🇦🇺Campbelltown, South Australia, Australia
Oregon Health & Science University
🇺🇸Portland, Oregon, United States
Paddington Testing Co, Inc.
🇺🇸Philadelphia, Pennsylvania, United States
Synexus Clinical Research US, Inc.
🇺🇸Anderson, South Carolina, United States
MUSC SCTR Research Nexus Clinic and Laboratory
🇺🇸Charleston, South Carolina, United States
Health Concepts
🇺🇸Rapid City, South Dakota, United States
Tanenbaum Dermatology Center
🇺🇸Memphis, Tennessee, United States
International Clinical Research - Tennessee LLC
🇺🇸Murfreesboro, Tennessee, United States
The University of Texas Health Science Center Houston
🇺🇸Bellaire, Texas, United States
Menter Dermatology Research Institute
🇺🇸Dallas, Texas, United States
Virginia Dermatology and Skin Cancer Center
🇺🇸Norfolk, Virginia, United States
Dermatology Associates of Seattle
🇺🇸Seattle, Washington, United States
Dermatology Specialists of Spokane
🇺🇸Spokane, Washington, United States
Multicare Institute for Research and Innovation
🇺🇸Tacoma, Washington, United States
Hospital Universitario Austral
🇦🇷Pilar, Buenos Aires, Argentina
CINME Centro de Investigaciones Metabolicas
🇦🇷C.a.b.a, Argentina
St George Dermatology & Skin Cancer Centre
🇦🇺Kogarah, New South Wales, Australia
Australian Clinical Research Network
🇦🇺Maroubra, New South Wales, Australia
Royal North Shore Hospital
🇦🇺Saint Leonards NSW, Australia
The Skin Hospital
🇦🇺Westmead, New South Wales, Australia
The Skin Centre
🇦🇺Benowa, Queensland, Australia
Skin Health Institute Inc.
🇦🇺Carlton, Victoria, Australia
University Hospital Brussels
🇧🇪Brussels, Belgium
University Hospital Antwerp
🇧🇪Edegem, Belgium
Tecnolab Medicina Diagnostica
🇧🇷Santo Andre, SP, Brazil
IBPClin Pesquisa Clinica
🇧🇷Rio de Janeiro, Brazil
MHAT Dobrich AD
🇧🇬Dobrich, Bulgaria
DermEdge Research
🇨🇦Mississauga, Ontario, Canada
CEC Spa
🇨🇱Santiago, Región Metropolitana, Chile
MIRES (M Y F Estudios Clínicos Limitada)
🇨🇱Santiago, Región Metropolitana, Chile
Peking University First Hospital
🇨🇳Beijing, Beijing, China
The First Affiliated Hospital Of Fujian Medical University
🇨🇳Fuzhou, Fujian, China
Children's Hospital of Wisconsin Translational Research Unit
🇺🇸Milwaukee, Wisconsin, United States
CONEXA Investigación Clínica S.A.
🇦🇷Caba, Buenos Aires, Argentina
Framingham Centro Medico
🇦🇷La Plata, Buenos Aires, Argentina
Servicio de Investigacion de Patolog-ias Alergicas del Instituto ABC - Rosario
🇦🇷Rosario, Santa FE, Argentina
Psoriahue Medicina Interdisciplinaria
🇦🇷C.a.b.a., Argentina
Woden Dermatology
🇦🇺Phillip, Australian Capital Territory, Australia
Eastern Health - Box Hill Hospital
🇦🇺Box Hill, Victoria, Australia
Sinclair Dermatology
🇦🇺East Melbourne, Victoria, Australia
Royal Melbourne Hospital
🇦🇺Parkville, Australia
The Royal Children's Hospital
🇦🇺Parkville, Victoria, Australia
Emeritus Research
🇦🇺Camberwell, Australia
Cliniques Universitaires Saint-Luc
🇧🇪Bruxelles, Belgium
Instituto de Dermatologia e Estética do Brasil LTDA
🇧🇷Rio de Janeiro, RJ, Brazil
Associacao dos Funcionarios Públicos do Estado do Rio Grande do Sul - Hospital Ernesto Dornelles
🇧🇷Porto Alegre, RS, Brazil
Fundacao do ABC - Faculdade de Medicina do ABC
🇧🇷Santo Andre, SP, Brazil
Pesquisare Saude S/S Ltda
🇧🇷Santo Andre, SP, Brazil
Tecnolab - Unidade Matriz
🇧🇷Sao Bernardo do Campo, SP, Brazil
MC Asklepii" OOD
🇧🇬Dupnitsa, Bulgaria
MHAT ''Dr. Tota Venkova'' AD
🇧🇬Gabrovo, Bulgaria
Military Medical Academy MHAT Sofia
🇧🇬Sofia, Bulgaria
Dermatology Clinic "Sofia" - group practice for specialized outpatient medical care
🇧🇬Sofia, Bulgaria
"Mc Synexus Sofia" Eood
🇧🇬Sofia, Bulgaria
Huashan Hospital Fudan University
🇨🇳Shanghai, Shanghai, China
Tianjin Medical University General Hospital, Dermatological Department
🇨🇳Tianjin, Tianjin, China
Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University
🇨🇳Hangzhou, Zhejiang, China
University of British Columbia Department of Dermatology and Skin Science
🇨🇦Vancouver, British Columbia, Canada
Karma Clinical Trials, Inc.
🇨🇦St. John's, Newfoundland and Labrador, Canada
Kingsway Clinical Research
🇨🇦Etobicoke, Ontario, Canada
Intermed groupe santé
🇨🇦Chicoutimi, Quebec, Canada
Centre de Recherche Saint-Louis
🇨🇦Quebec, Canada
Centro Medico SkinMed Limitada
🇨🇱Santiago, Region Metropolitana, Chile
The Third Affiliated Hospital, Sun Yat-sen University
🇨🇳Guangzhou, Guangdong, China
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
🇨🇳Wuhan, Hubei, China
The Third Xiangya Hospital of Central South University, Dermatological department
🇨🇳Changsha, Hunan, China
The First Affiliated Hospital With Nanjing University
🇨🇳Nanjing, Jiangsu, China
Shandong Provincial Institute of Dermatology and Venereology & Shandong Provincial Hospital for Skin
🇨🇳Jinan, Shandong, China
The First Affiliated Hospital of Zhejiang University School of Medicine/Dermatology and STD Dept
🇨🇳Hangzhou, Zhejiang, China
Hangzhou Third Hospital
🇨🇳Hangzhou, Zhejiang, China
Xin Hua Hospital Affiliated to Shanghai Jiaotong University School of Medicine/Dermatology
🇨🇳Shanghai, China
Jinan Central Hospital
🇨🇳Jinan, Shandong, China
The Second Affiliated Hospital of Zhejiang University School of Medicine/Dermatology Dept
🇨🇳Hangzhou, Zhejiang, China
Zhejiang Provincial People's Hospital/Dermatology Department
🇨🇳Hangzhou, Zhejiang, China
The Second Affiliated Hospital of Army Medical University,PLA
🇨🇳Chongqing, China
Lekarna Pod Kankem
🇨🇿Kunta Hora, Czechia
Lekarna U Stribrneho orla (Pharmacy)
🇨🇿Nachod, Czechia
Universitätsklinikum Erlangen
🇩🇪Erlangen, Germany
Soroka University Medical Center
🇮🇱Beer Sheva, Israel
The Chaim Sheba Medical Center
🇮🇱Ramat-Gan, Israel
Tel-Aviv Sourasky Medical Center
🇮🇱Tel-Aviv, Israel
AOU Policlinico Sant'Orsola Malpighi
🇮🇹Bologna, BO, Italy
Universita degli Studi G. D'Annunzio -CeSi-MeT
🇮🇹Chieti, CH, Italy
Ospedale Policlinico San Martino
🇮🇹Genova, GE, Italy
Queen's square Medical Facilities Queen's square Dermatology and Allergology
🇯🇵Yokohama, Kanagawa, Japan
Noguchi Dermatology Clinic
🇯🇵Kamimashiki-gun, Kumamoto, Japan
Osaka Habikino Medical Center
🇯🇵Habikino, Osaka, Japan
Yoshioka Dermatology Clinic
🇯🇵Neyagawa, Osaka, Japan
Dermatology and Ophthalmology Kume Clinic
🇯🇵Sakai, Osaka, Japan
Tokyo Medical University Hospital
🇯🇵Shinjyuku-ku, Tokyo, Japan
Hoshikuma Dermatology・Allergy Clinic
🇯🇵Fukuoka, Japan
Matsuda Tomoko Dermatological Clinic
🇯🇵Fukuoka, Japan
Korea University Ansan Hospital
🇰🇷Ansan-si, Gyeonggi-do, Korea, Republic of
Soon Chun Hyang University Bucheon Hospital
🇰🇷Bucheon-si, Gyeonggi-do, Korea, Republic of
Kyungpook National University Hospital
🇰🇷Daegu, Korea, Republic of
Chungnam National University Hospital CNUH
🇰🇷Daejeon, Korea, Republic of
Chonnam National University Hospital
🇰🇷Gwangju, Korea, Republic of
The Catholic University of Korea, Incheon St. Mary's Hospital
🇰🇷Incheon, Korea, Republic of
Inha University Hospital
🇰🇷Incheon, Korea, Republic of
Korea University Anam Hospital
🇰🇷Seoul, Korea, Republic of
Severance Hospital, Yonsei Univ. Health System
🇰🇷Seoul, Korea, Republic of
The Catholic University of Korea, Seoul St. Mary's Hospital
🇰🇷Seoul, Korea, Republic of
Chung-Ang University Hospital
🇰🇷Seoul, Korea, Republic of
Unidad de Atención Médica e Investigación en Salud
🇲🇽Mérida, Yucatán, Mexico
Derma Norte del Bajio S.C.
🇲🇽Aguascalientes, Mexico
NZOZ Specjalistyczny Osrodek Dermatologiczny DERMAL s.c.
🇵🇱Bialystok, Poland
KLIMED Marek Klimkiewicz
🇵🇱Białystok, Poland
Clinica Dermatoestetica Prywatny Gabinet Dermatologiczny i Alergologiczny
🇵🇱Bydgoszcz, Poland
Synexus Polska Sp. z o.o. Oddzial w Czestochowie
🇵🇱Czestochowa, Poland
Centralny Szpital Kliniczny Ministerstwa Spraw Wewnetrznych i Administracji w Warszawie
🇵🇱Warszawa, Poland
RCMed Oddzial Warszawa
🇵🇱Warszawa, Poland
Carpe Diem Centrum Medycyny Estetycznej
🇵🇱Warszawa, Poland
ETG Warszawa
🇵🇱Warszawa, Poland
SC Centrul Medical de Diagnostic si Tratament Ambulator Neomed SRL
🇷🇴Brasov, JUD. Brasov, Romania
Cabinet Medical de Dermatovenerologie Prof. Dr. Orasan Remus Ioan
🇷🇴Cluj-Napoca, Jud. Cluj, Romania
SC Delta Health Care SRL
🇷🇴Bucharest, Romania
SBIH "Chelyabinsk Regional Clinical Dermatovenerology dispensary"
🇷🇺Chelyabinsk, Russian Federation
Limited Liability Company "Medical Center "Rheuma-Med"
🇷🇺Kemerovo, Russian Federation
Clinic of FSBEI HE Kirov SMU MOH Russia
🇷🇺Kirov, Russian Federation
FSBI "State Research Centre of Dermatovenereology and Cosmetology" MoH RF
🇷🇺Moscow, Russian Federation
LLC "Pierre Wolkenstein Clinic of Skin Diseases"
🇷🇺Saint-Petersburg, Russian Federation
FSBEI HE "St. Petersburg State Pediatric Medical University" MoH RF
🇷🇺Saint-Petersburg, Russian Federation
"Medical Research Institute", LLC
🇷🇺Saint-Petersburg, Russian Federation
FSBEI HE I.P.Pavlov SPbSMU MOH Russia
🇷🇺Saint-Petersburg, Russian Federation
Military Medical Academy
🇷🇸Belgrade, Serbia
Summit Clinical Research, s.r.o.
🇸🇰Bratislava - Mestská Cast Nove Mesto, Slovakia
Hospital Sant Joan de Deu
🇪🇸Esplugues de Llobregat, Barcelona, Spain
Hospital Universitario de Gran Canaria Dr. Negrin
🇪🇸Las Palmas de Gran Canaria, LAS Palmas, Spain
Hospital Universitario Fundacion Alcorcon
🇪🇸Alcorcon, Madrid, Spain
Hospital Universitario Puerta de Hierro de Majadahonda
🇪🇸Majadahonda, Madrid, Spain
Hospital Clinic de Barcelona
🇪🇸Barcelona, Spain
Hospital de la Santa Creu i Sant Pau Servicio de Dermatologia
🇪🇸Barcelona, Spain
Consorcio Hospital General Universitario de Valencia
🇪🇸Valencia, Spain
Hospital Universitario y Politecnico La Fe
🇪🇸Valencia, Spain
Hospital Universitario Miguel Servet
🇪🇸Zaragoza, Spain
Taipei Veterans General Hospital
🇨🇳Taipei, Taiwan (r.o.c), Taiwan
Kaohsiung Medical University Chung-Ho Memorial Hospital
🇨🇳Kaohsiung, Taiwan
Taipei Medical University-Shuang Ho Hospital
🇨🇳New Taipei City, Taiwan
Chung Shan Medical University Hospital
🇨🇳Taichung, Taiwan
Taichung Veterans General Hospital
🇨🇳Taichung, Taiwan
National Cheng-Kung University Hospital
🇨🇳Tainan, Taiwan
National Taiwan University Hospital
🇨🇳Taipei, Taiwan
Mackay Memorial Hospital
🇨🇳Taipei, Taiwan
Chang Gung Memorial Hospital Linkou Branch
🇨🇳Taoyuan City, Taiwan
Medinova Research
🇬🇧Wokingham, Berkshire, United Kingdom
MeDiNova West London Quality Research Sites
🇬🇧Wokingham, Berkshire, United Kingdom
Plymouth Hospitals NHS Trust, Derriford Hospital
🇬🇧Plymouth, Devon, United Kingdom
Royal free London NHS Foundation Trust
🇬🇧London, Greater London, United Kingdom
MeDiNova South London Quality Research Site
🇬🇧Orpington, Kent, United Kingdom
Accellacare North London
🇬🇧Northwood, Middlesex, United Kingdom
Barnsley Hospital NHS Foundation Trust
🇬🇧Barnsley, South Yorkshire, United Kingdom
Sheffield Children's NHS Foundation Trust
🇬🇧Sheffield, South Yorkshire, United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust, Northern General Hospital
🇬🇧Sheffield, South Yorkshire, United Kingdom
Accellacare Yorkshire
🇬🇧Shipley, United Kingdom