MedPath

Study to Evaluate Efficacy and Safety of PF-04965842 With or Without Topical Medications in Subjects Aged 12 Years and Older With Moderate to Severe Atopic Dermatitis

Phase 3
Active, not recruiting
Conditions
Dermatitis, Atopic
Interventions
Registration Number
NCT03422822
Lead Sponsor
Pfizer
Brief Summary

B7451015 is a Phase 3 study to evaluate Abrocitinib with or without Topical Medications in patients aged 12 years and older who have moderate to severe atopic dermatitis and have completed a qualifying parent study. The efficacy and safety of two dosage strengths of Abrocitinib, 100 mg and 200 mg taken orally once daily, will be evaluated over variable lengths of study participation. The study consists of a 92 week initial treatment period followed by a variable length secondary treatment period during which subjects will receive treatment with open-label abrocitinib until availability of commercial product in their country, or until the sponsor terminates the study in that country.

The B7451015 study also includes a sub-study evaluating whether abrocitinib has any potential effects on adolescent bone with regard to abnormal bone findings in knee MRI. The sub-study will be conducted in selected countries at selected sites. Eligible subjects are those who were 12 to \<18 years of age at the screening visit of the qualifying parent study and who are currently participating in the main B7451015 study. The sub-study will include serial Magnetic Resonance Imaging (MRI) annually and continue until all enrolled subjects are 18 years of age and have been imaged at least once or have discontinued/withdrawn.

Detailed Description

Not available

Recruitment & Eligibility

Status
ACTIVE_NOT_RECRUITING
Sex
All
Target Recruitment
3162
Inclusion Criteria
  1. Evidence of a personally signed and dated informed consent document indicating that the subject or their parent(s)/legal guardian, if applicable, have been informed of all pertinent aspects of the study.

  2. Male or female subjects of 12 years of age or older, at the time of informed consent and meets inclusion criterion for minimum body weight (if applicable) from qualifying Parent study. Adolescent subjects below the age of 18 years old (or country-specific age of majority) will only be enrolled in this study if instructed by the sponsor and approved by the country or regulatory/health authority. If these approvals have not been granted, only subjects aged 18 years (or country-specific age of majority) and older will be enrolled.

  3. Willing and able to comply with scheduled visits, treatment plan, laboratory tests and other study procedures.

  4. Must have completed the full treatment period of a qualifying Parent study OR must have completed the full rescue treatment period of a qualifying Parent study (if applicable) OR must have completed the full open-label run-in period in B7451014 and did not meet the protocol-specified response criteria at Week 12.

  5. Female subjects who are of childbearing potential (which includes all female subjects aged 12 years and older, regardless of whether they have experienced menarche) must ot be intending to become pregnant, currently pregnant, or lactating. The following onditions apply:

    1. Female subjects of childbearing potential must have a confirmed negative pregnancy test prior to allocation to treatment.
    2. Female subjects of childbearing potential must agree to use a highly effective method of contraception (as per Section 4.4.1) for the duration of the active treatment period and for at least 28 days after the last dose of investigational product.

For Czech Republic only, 5 b. is revised and 5 c. is added to require:

Female subjects of childbearing potential 15 years of age who are at risk of pregnancy must agree to use a highly effective method of contraception for the duration of the active treatment period and for at least 28 days after the last dose of investigational product.

c. Female subjects less than 15 years of age must not be sexually active, and abstinence per the below definition should be confirmed prior to enrollment. NOTE: Sexual abstinence, defined as completely and persistently refraining from all heterosexual intercourse (including during the entire period of risk associated with the study treatments) may obviate the need for contraception ONLY if this is the preferred and usual lifestyle of the subject.

  1. Female subjects of non-childbearing potential must meet at least 1 of the following criteria:

  2. Have undergone a documented hysterectomy and/or bilateral oophorectomy;

  3. Have medically confirmed ovarian failure; or

  4. Achieved postmenopausal status, defined as follows: cessation of regular menses for at least 12 consecutive months with no alternative pathological or physiological cause and have a serum follicle-stimulating hormone (FSH) level confirming the postmenopausal state. All other female subjects (including female subjects with tubal ligations) are considered to be of childbearing potential. 7. Must agree to avoid prolonged exposure to the sun and not to use tanning booths, sun lamps or other ultraviolet light sources during the study.

    1. Must agree to avoid use of prohibited medications throughout the duration of the study. Exclusion Criteria
    2. Other acute or chronic medical or psychiatric condition including recent (within the past year) or active suicidal ideation or behavior or laboratory abnormality that may increase the risk associated with study participation or investigational product administration or may interfere with the interpretation of study results and, in the judgment of the investigator, would make the subject inappropriate for entry into this study.
    3. Currently have active forms of other inflammatory skin diseases, ie, not AD or have evidence of skin conditions (eg, psoriasis, seborrheic dermatitis, Lupus) at the time of Day -1 that would interfere with evaluation of atopic dermatitis or response to treatment.
    4. Discontinued from treatment (or rescue treatment period/open-label run-in period, if applicable) early in a qualifying Parent study OR triggered a discontinuation criterion at any point during the qualifying Parent study which in the opinion of the investigator, or sponsor, is an ongoing safety concern.
    5. Ongoing adverse event in the qualifying Parent study which in the opinion of the investigator, or sponsor, is an ongoing safety concern.
    6. Investigator site staff members directly involved in the conduct of the study and their family members, site staff members otherwise supervised by the investigator, or subjects who are Pfizer employees, including their family members, directly involved in the conduct of the study.

    There are also additional separate inclusion and exclusion criteria to assess eligibility specifically for the B7451015 MRI sub-study.

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Exclusion Criteria

Not provided

Read More

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Abrocitinib 100 mgPlaceboAbrocitinib 100 mg QD PO
Abrocitinib 200 mgAbrocitinib 100 mgAbrocitinib 200 mg QD PO
Abrocitinib 100 mgAbrocitinib 100 mgAbrocitinib 100 mg QD PO
Abrocitinib 200 mgAbrocitinib 200 mgAbrocitinib 200 mg QD PO
Primary Outcome Measures
NameTimeMethod
Change from baseline in clinical laboratory valuesThroughout study regardless of availability of commercial product until at least 2024, or until the sponsor terminates the study; an estimated maximum of 8 years

Change from baseline in clinical laboratory values

Treatment emergent adverse eventsThroughout study regardless of availability of commercial product until at least 2024, or until the sponsor terminates the study; an estimated maximum of 8 years

The incidence of treatment emergent adverse events

Serious adverse events and adverse events leading to discontinuationThroughout study regardless of availability of commercial product until at least 2024, or until the sponsor terminates the study; an estimated maximum of 8 years

The incidence of serious adverse events and adverse events leading to discontinuation

Change from baseline in electrocardiogram (ECG) measurementsThroughout study regardless of availability of commercial product until at least 2024, or until the sponsor terminates the study; an estimated maximum of 8 years

Change from baseline in electrocardiogram (ECG) measurements

Change from baseline in vital signsThroughout study regardless of availability of commercial product until at least 2024, or until the sponsor terminates the study; an estimated maximum of 8 years

Change from baseline in vital signs

Secondary Outcome Measures
NameTimeMethod
Investigator's Global Assessment (IGA)Baseline, Week 2, Week 4, Week 12, Week 24, Week 36, Week 48, Week 60, Week 72, Week 84, Week 92

Response based on the IGA score of clear (0) or almost clear (1) (on a 5 point scale) and a reduction from baseline of \>=2 points at all scheduled time points

Patient Oriented Eczema Measure (POEM)Baseline, Week 12, Week 24, Week 36, Week 48, Week 60, Week 72, Week 84, Week 92

Change from baseline in POEM at all scheduled time points

Patient Global Assessment (PtGA)Baseline, Week 2, Week 4, Week 12, Week 24, Week 36, Week 48, Week 60, Week 72, Week 84, Week 92

Change from baseline of PtGA at all scheduled time points

Dermatology Life Quality Index (DLQI) or Children's DLQI (CDLQI)Baseline, Week 12, Week 24, Week 36, Week 48, Week 60, Week 72, Week 84, Week 92

Change from baseline in DLQI or CDLQI at all scheduled time points

Hospital Anxiety and Depression Scale (HADS)Baseline, Week 12, Week 24, Week 36, Week 48, Week 60, Week 64, Week 72, Week 84, Week 92, Week 96

Change from baseline in HADS at all scheduled time points

Pruritus Numerical Rating Scale (NRS)Baseline, Week 2, Week 4, Week 12, Week 24, Week 36, Week 48, Week 60, Week 72, Week 84, Week 92

Response based on an improvement greater than or equal to 3 points and greater than or equal to 4 points from baseline in the pruritus NRS at all scheduled time points

Change in height standard deviation score (SDS)Throughout study regardless of availability of commercial product until at least 2024, or until the sponsor terminates the study; an estimated maximum of 8 years

Change in height standard deviation score (SDS) at all scheduled time points

Eczema Area and Severity Index (EASI)Throughout study regardless of availability of commercial product until at least 2024, or until the sponsor terminates the study; an estimated maximum of 8 years

Response based on greater than or equal to 50%, 75% and 90% improvement from baseline in the EASI total score (EASI50, EASI75, and EASI90) at all scheduled time points

Body Surface Area (BSA) affectedThroughout study regardless of availability of commercial product until at least 2024, or until the sponsor terminates the study; an estimated maximum of 8 years

Change from baseline in the percentage BSA affected at all scheduled time points

Steroid-Free DaysThroughout study regardless of availability of commercial product until at least 2024, or until the sponsor terminates the study; an estimated maximum of 8 years

Number of steroid-free days will be assessed throughout the duration of the study.

Serum Hs-CRP LevelsThroughout study regardless of availability of commercial product until at least 2024, or until the sponsor terminates the study; an estimated maximum of 8 years

Serum Hs-CRP levels at all scheduled time points

Proportion of abnormal findings in knee MRI in adolescent subjects exposed to abrocitinib 100mg and 200mg QDThroughout sub-study until all enrolled subjects are 18 years of age and have been imaged at least once or have discontinued or withdrawn; an estimated maximum of 4 years

Proportion of abnormal findings in knee MRI in adolescent subjects exposed to abrocitinib 100mg and 200mg QD

EuroQol Quality of Life 5 Dimension 5 Level Scale (EQ-5D-5L) or EuroQol Quality of Life 5 Dimension Youth Scale (EQ-5D-Y)Baseline, Week 24, Week 48, Week 60, Week 72, Week 92

Change from baseline of EQ-5D-5L or EQ-5D-Y at all scheduled time points

Trial Locations

Locations (541)

University of British Columbia Department of Dermatology and Skin Science

🇨🇦

Vancouver, British Columbia, Canada

The Centre for Clinical Trials

🇨🇦

Oakville, Ontario, Canada

AvantDerm

🇨🇦

Toronto, Ontario, Canada

Research Toronto

🇨🇦

Toronto, Ontario, Canada

Manna Research Inc.(Toronto)

🇨🇦

Toronto, Ontario, Canada

Innovaderm Research Inc.

🇨🇦

Montreal, Quebec, Canada

K.Papp Clinical Research Inc.

🇨🇦

Waterloo, Ontario, Canada

MIRES (M Y F Estudios Clínicos Limitada)

🇨🇱

Santiago, Región Metropolitana, Chile

CEC Spa

🇨🇱

Santiago, Región Metropolitana, Chile

Dermatology Department, Shanghai Changzheng Hospital

🇨🇳

Shanghai, China

Fakultni Nemocnice Ostrava, Kozni oddeleni

🇨🇿

Ostrava - Poruba, Czechia

CCR Ostrava, s.r.o.

🇨🇿

Ostrava, Czechia

Apavar Lekarna

🇨🇿

Ostrava, Czechia

PRATIA Pardubice a.s.

🇨🇿

Pardubice, Czechia

Nemocnice Pardubickeho kraje, a.s., Pardubicka nemocnice

🇨🇿

Pardubice, Czechia

Lekarna Pod Platany (Pharmacy)

🇨🇿

Praha 10, Czechia

Turun yliopistollinen keskussairaala

🇫🇮

Turku, Finland

Lekarna Pod Platany

🇨🇿

Praha 10, Czechia

CCR Prague, s.r.o.

🇨🇿

Praha 3, Czechia

PRATIA Prague s.r.o.

🇨🇿

Praha 3, Czechia

Dermatovenerologicka ambulance

🇨🇿

Svitavy, Czechia

Krajska zdravotni a.s., Masarykova nemocnice o.z.

🇨🇿

Usti nad Labem, Czechia

Terveystalo Tampere

🇫🇮

Tampere, Finland

Lekarna Masarykovy nemocnice v Usti nad Labem, o.z.

🇨🇿

Usti nad Labem, Czechia

Dermazentrum Augsburg

🇩🇪

Augsburg, Germany

Velocity Clinical Research, Leipzig

🇩🇪

Leipzig, Sachsen, Germany

Hautzentrum Friedrichshain Studien

🇩🇪

Berlin, Germany

Charite-Universitaetsmedizin Berlin

🇩🇪

Berlin, Germany

Rothhaar Studien GmbH

🇩🇪

Berlin, Germany

Klinikum Bielefeld Rosenhoehe

🇩🇪

Bielefeld, Germany

Universitaetsklinikum Bonn

🇩🇪

Bonn, Germany

Klinische Forschung Dresden GmbH

🇩🇪

Dresden, Germany

Universitaetsklinikum Carl Gustav Carus der Technischen Universitaet Dresden

🇩🇪

Dresden, Germany

IKF Pneumologie GmbH & Co KG; Institut für klinische Forschung

🇩🇪

Frankfurt, Germany

Medizinische Hochschule Hannover

🇩🇪

Hannover, Germany

Lynderm Research Inc.

🇨🇦

Markham, Ontario, Canada

Toronto Research Centre

🇨🇦

Toronto, Ontario, Canada

Universitaetsklinikum Schleswig-Holstein, Campus Luebeck

🇩🇪

Luebeck, Germany

Dermatologische Gemeinschaftspraxis

🇩🇪

Mahlow, Germany

University of Muenster

🇩🇪

Muenster, Germany

Klinische Forschung Schwerin GmbH

🇩🇪

Schwerin, Germany

Pro Familia Altera Sp. z o.o.

🇵🇱

Katowice, Poland

Debreceni Egyetem Klinikai Kozpont

🇭🇺

Debrecen, Hungary

CRU Hungary Kft.

🇭🇺

Encs, Hungary

Synexus Magyarország Egészségügyi Szolgáltató Kft. Synexus Gyula DRS

🇭🇺

Gyula, Hungary

Trial Pharma Kft.

🇭🇺

Püspökladány, Hungary

Bugát Pál Kórház, Bőrgyógyászati Szakrendelés

🇭🇺

Gyöngyös, Hungary

Pecsi Tudomanyegyetem Klinikai Kozpont, Bor-,Nemikortani es Onkodermatologiai Klinika

🇭🇺

Pecs, Hungary

ALLERGO-DERM BAKOS Kft.

🇭🇺

Szolnok, Hungary

The Chaim Sheba Medical Center

🇮🇱

Ramat-Gan, Israel

Tel-Aviv Sourasky Medical Center

🇮🇱

Tel-Aviv, Israel

AOU Policlinico Sant'Orsola Malpighi

🇮🇹

Bologna, BO, Italy

Ospedale Policlinico San Martino

🇮🇹

Genova, GE, Italy

AOU Policlinico di Modena Struttura complessa di Dermatologia

🇮🇹

Modena, MO, Italy

Gabinet Dermatologiczny Beata Krecisz

🇵🇱

Kielce, Poland

ASST Fatebenefratelli Sacco

🇮🇹

Milano, Italy

IFO lstituto Dermatologico San Gallicano IRCCS

🇮🇹

Roma, Italy

Universita del Sacro Cuore, Policlinico Agostino Gemelli, Istituto Di Dermatologia

🇮🇹

Rome, Italy

Takagi Dermatological Clinic Branch

🇯🇵

Obihiro, Hokkaido, Japan

Kawashima Dermatology Clinic

🇯🇵

Ichikawa, Chiba, Japan

Takagi Dermatological Clinic

🇯🇵

Obihiro, Hokkaido, Japan

Dermatology Shimizu Clinic

🇯🇵

Kobe, Hyogo, Japan

Queen's square Medical Facilities Queen's square Dermatology and Allergology

🇯🇵

Yokohama, Kanagawa, Japan

Noguchi Dermatology Clinic

🇯🇵

Kamimashiki-gun, Kumamoto, Japan

Malopolskie Centrum Kliniczne

🇵🇱

Krakow, Poland

Osaka Habikino Medical Center

🇯🇵

Habikino, Osaka, Japan

Yoshioka Dermatology Clinic

🇯🇵

Neyagawa, Osaka, Japan

Dermatology and Ophthalmology Kume Clinic

🇯🇵

Sakai, Osaka, Japan

The Ohio State University Wexner Medical Center

🇺🇸

Columbus, Ohio, United States

Fukuwa Clinic

🇯🇵

Chuo-ku, Tokyo, Japan

Sumire Dermatology Clinic

🇯🇵

Edogawa-ku, Tokyo, Japan

Matsuyama Dermatology Clinic

🇯🇵

Nakano-ku, Tokyo, Japan

Tokyo Medical University Hospital

🇯🇵

Shinjyuku-ku, Tokyo, Japan

Centrum Medyczne Plejady

🇵🇱

Krakow, Poland

Matsuda Tomoko Dermatological Clinic

🇯🇵

Fukuoka, Japan

Sanrui Hifuka

🇯🇵

Saitama, Japan

Korea University Ansan Hospital

🇰🇷

Ansan-si, Gyeonggi-do, Korea, Republic of

Soon Chun Hyang University Bucheon Hospital

🇰🇷

Bucheon-si, Gyeonggi-do, Korea, Republic of

Chungnam National University Hospital CNUH

🇰🇷

Daejeon, Korea, Republic of

Chonnam National University Hospital

🇰🇷

Gwangju, Korea, Republic of

Korea University Anam Hospital

🇰🇷

Seoul, Korea, Republic of

The Catholic University of Korea, Incheon St. Mary's Hospital

🇰🇷

Incheon, Korea, Republic of

Inha University Hospital

🇰🇷

Incheon, Korea, Republic of

The Catholic University of Korea, Seoul St. Mary's Hospital

🇰🇷

Seoul, Korea, Republic of

Chung-Ang University Hospital

🇰🇷

Seoul, Korea, Republic of

Hallym University Kangnam Sacred Heart Hospital

🇰🇷

Seoul, Korea, Republic of

Health Centre 4 Ltd. Diagnostics Centre

🇱🇻

Riga, Latvia

Aesthetic dermatology clinic of Prof. J. Kisis

🇱🇻

Riga, Latvia

Health Centre 4 Ltd, Dermatology Clinics

🇱🇻

Riga, Latvia

Health and Aesthetics Ltd

🇱🇻

Riga, Latvia

Outpatient Clinic Of Ventspils

🇱🇻

Ventspils, Latvia

Hospital Infantil de Mexico Federico Gomez

🇲🇽

Del. Cuauhtemoc, Ciudad DE Mexico, Mexico

Clinical Research Institute S.C.

🇲🇽

Saltillo, Coahuila, Mexico

JM Research SC

🇲🇽

Cuernavaca, Morelos, Mexico

Derma Norte del Bajio S.C.

🇲🇽

Aguascalientes, Mexico

Centro de Investigacion Integral MEDIVEST, S.C.

🇲🇽

Chihuahua, Mexico

Cryptex Investigación Clínica, S.A. de C.V.

🇲🇽

Mexico City, Mexico

Arke Estudios Clinicos Sa De Cv

🇲🇽

Mexico city, Mexico

Eukarya Pharmasite S.C.

🇲🇽

Monterrey, Mexico

SMIQ, S. de R. L. de C.V.

🇲🇽

Queretaro, Mexico

Sociedad de Metabolismo y Corazon S.C.

🇲🇽

Veracruz, Mexico

ETG Warszawa

🇵🇱

Warszawa, Poland

Universitair Medisch Centrum (UMC) Utrecht

🇳🇱

Utrecht, Netherlands

KLIMED Marek Klimkiewicz

🇵🇱

Białystok, Poland

Clinica Dermatoestetica Prywatny Gabinet Dermatologiczny i Alergologiczny

🇵🇱

Bydgoszcz, Poland

Silmedic Sp. z o.o., Oddzial w Katowicach

🇵🇱

Katowice, Poland

Synexus Polska Sp. z o.o. Oddzial w Czestochowie

🇵🇱

Czestochowa, Poland

Neutrum Lekarze M. Hlebowicz i Partnerzy Spolka Partnerska

🇵🇱

Gdansk, Poland

MCBK

🇵🇱

Grodzisk Mazowiecki, Poland

Synexus Polska Sp. z o.o. Oddzial w Katowicach

🇵🇱

Katowice, Poland

MULTIKLINIKA Salute Sp. z o.o.

🇵🇱

Katowice, Poland

Centrum Badan Klinicznych JCI

🇵🇱

Krakow, Poland

Centrum Nowoczesnych Terapii "DOBRY LEKARZ" sp. z o.o.

🇵🇱

Krakow, Poland

AWP Klinika Dermatologii Pod Fortem Anna Wojas-Pelc

🇵🇱

Krakow, Poland

Centrum Medyczne Promed

🇵🇱

Krakow, Poland

Krakowskie Centrum Medyczne Sp. z o.o.

🇵🇱

Krakow, Poland

Prywatna Praktyka Lekarska - Adam Smialowski INTERMED KSAWEROW

🇵🇱

Ksawerow, Poland

Centrum Terapii Wspolczesnej J.M. Jasnorzewska Spolka Komandytowo-Akcyjna

🇵🇱

Lodz, Poland

Dermoklinika-Centrum Medyczne s.c. M. Kierstan, J. Narbutt, A. Lesiak

🇵🇱

Lodz, Poland

KO-MED Centra Kliniczne Lublin II

🇵🇱

Lublin, Poland

NZOZ "Med-Laser" Borzecki Spolka Jawna

🇵🇱

Lublin, Poland

Dermedic Jacek Zdybski

🇵🇱

Ostrowiec Swietokrzyski, Poland

LIFT-MED Spolka Akcyjna

🇵🇱

Rybnik, Poland

Kliniczny Szpital Wojewodzki nr 1 im. F. Chopina, Klinika Dermatologii

🇵🇱

Rzeszow, Poland

Andrzej Krolicki, Tomasz Kochanowski "Laser Clinic" S.C.

🇵🇱

Szczecin, Poland

Alergo-Med Specjalistyczna Przychodnia Lekarska Sp. z o.o.

🇵🇱

Tarnow, Poland

SBI RR "Regional Clinical Skin and Veneral Dispensary"

🇷🇺

Ryazan, Russian Federation

Taipei Veterans General Hospital

🇨🇳

Taipei, Taiwan (r.o.c), Taiwan

Chung Shan Medical University Hospital

🇨🇳

Taichung, Taiwan

Clinical Trials Solutions

🇺🇸

Miami, Florida, United States

Baumann Cosmetic and Research Institute

🇺🇸

Miami, Florida, United States

Iidabashi Skin Clinic

🇯🇵

Chiyoda-ku, Tokyo, Japan

University of California San Diego Dermatology

🇺🇸

San Diego, California, United States

Clinical Research Institute, Inc.

🇺🇸

Minneapolis, Minnesota, United States

Texas Dermatology and Laser Specialists

🇺🇸

San Antonio, Texas, United States

Peking University First Hospital

🇨🇳

Beijing, Beijing, China

Beijing Friendship Hospital, Capital Medical University

🇨🇳

Beijing, Beijing, China

The First Affiliated Hospital Of Fujian Medical University

🇨🇳

Fuzhou, Fujian, China

The Third Affiliated Hospital, Sun Yat-sen University

🇨🇳

Guangzhou, Guangdong, China

Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology

🇨🇳

Wuhan, Hubei, China

The University of Hong Kong - Shenzhen Hospital

🇨🇳

Shenzhen, Guangdong, China

The Third Xiangya Hospital of Central South University, Dermatological department

🇨🇳

Changsha, Hunan, China

Dermatology Hospital of Jiangxi Province

🇨🇳

Nanchang, Jiangxi, China

Jinan Central Hospital

🇨🇳

Jinan, Shandong, China

Huashan Hospital Fudan University

🇨🇳

Shanghai, Shanghai, China

Shandong Provincial Institute of Dermatology and Venereology & Shandong Provincial Hospital for Skin

🇨🇳

Jinan, Shandong, China

Shanghai Dermatology Hospital

🇨🇳

Shanghai, China

Tianjin Medical University General Hospital, Dermatological Department

🇨🇳

Tianjin, Tianjin, China

First Affiliated Hospital of Kunming Medical University

🇨🇳

Kunming, Yunnan, China

The First Affiliated Hospital of Zhejiang University School of Medicine/Dermatology and STD Dept

🇨🇳

Hangzhou, Zhejiang, China

The Second Affiliated Hospital of Zhejiang University School of Medicine/Dermatology Dept

🇨🇳

Hangzhou, Zhejiang, China

Synergy Dermatology

🇺🇸

San Francisco, California, United States

Total Skin and Beauty Dermatology Center, PC

🇺🇸

Birmingham, Alabama, United States

Clinical Research Center of Alabama, LLC

🇺🇸

Birmingham, Alabama, United States

University of Alabama at Birmingham Hospital Outreach Lab

🇺🇸

Birmingham, Alabama, United States

Henry Ford Medical Center, New Center One

🇺🇸

Detroit, Michigan, United States

Newton Clinical Research

🇺🇸

Oklahoma City, Oklahoma, United States

Oregon Medical Research Center

🇺🇸

Portland, Oregon, United States

Oregon Health & Science University

🇺🇸

Portland, Oregon, United States

Universita degli Studi G. D'Annunzio -CeSi-MeT

🇮🇹

Chieti, CH, Italy

MENSINGDERMA research GmbH

🇩🇪

Hamburg, Germany

ISA GmbH

🇩🇪

Berlin, Germany

Universitätsklinikum Erlangen

🇩🇪

Erlangen, Germany

Prof. MUDr.Petr Arenberger, DrSc. MBA

🇨🇿

Praha 1, Czechia

Hospital del Nino Jesus

🇪🇸

Madrid, Spain

SBI RR "Skin and Venereal Dispensary"

🇷🇺

Rostov-on-Don, Russian Federation

Limited Liability Company "Sanavita"

🇷🇺

Saint Petersburg, Russian Federation

"Medical Research Institute", LLC

🇷🇺

Saint-Petersburg, Russian Federation

Clinical Centre Nis

🇷🇸

Nis, Serbia

Fakultna nemocnica s poliklinikou Nove Zamky, Dermatovenerologicka klinika

🇸🇰

Nove Zamky, Slovakia

University of Alabama at Birmingham - Dermatology Research Clinic

🇺🇸

Birmingham, Alabama, United States

First OC Dermatology Research Inc

🇺🇸

Fountain Valley, California, United States

First OC Dermatology

🇺🇸

Fountain Valley, California, United States

Beach Allergy and Asthma Specialty Group, A Medical Corporation

🇺🇸

Long Beach, California, United States

Wallace Medical Group, Inc

🇺🇸

Los Angeles, California, United States

Mosaic Dermatology

🇺🇸

Santa Monica, California, United States

Wolverine Clinical Trials, Llc

🇺🇸

Santa Ana, California, United States

Clinical Science Institute

🇺🇸

Santa Monica, California, United States

Renaissance Research and Medical Group, Inc

🇺🇸

Cape Coral, Florida, United States

Skin Care Research

🇺🇸

Boca Raton, Florida, United States

Florida Academic Centers Research and Education, LLC

🇺🇸

Coral Gables, Florida, United States

Moonshine Research Center, Inc.

🇺🇸

Doral, Florida, United States

Homestead Research Institute

🇺🇸

Homestead, Florida, United States

Clinical Neuroscience Solutions, Inc.

🇺🇸

Memphis, Tennessee, United States

Solutions Through Advanced Research, Inc.

🇺🇸

Jacksonville, Florida, United States

C & R Research Services USA, Inc

🇺🇸

Kendall, Florida, United States

Savin Medical Group LLC

🇺🇸

Miami Lakes, Florida, United States

Global Health Clinical Trials Corp

🇺🇸

Miami, Florida, United States

Wellness Clinical Research, LLC

🇺🇸

Miami Lakes, Florida, United States

Suncoast Research Associates

🇺🇸

Miami, Florida, United States

La Salud Research Clinic, Inc.

🇺🇸

Miami, Florida, United States

Nicklaus Children's Hospital

🇺🇸

Miami, Florida, United States

Ciocca Dermatology, PA

🇺🇸

Miami, Florida, United States

Park Avenue Dermatology

🇺🇸

Orange Park, Florida, United States

INTERMED Medical Research Center, Inc

🇺🇸

Miami, Florida, United States

Integrated Clinical Research

🇺🇸

West Palm Beach, Florida, United States

IACT Health

🇺🇸

Columbus, Georgia, United States

Meridian Clinical Research

🇺🇸

Savannah, Georgia, United States

One Health Research Clinic

🇺🇸

Norcross, Georgia, United States

ASR, LLC

🇺🇸

Nampa, Idaho, United States

NorthShore University HealthSystem - Dermatology

🇺🇸

Skokie, Illinois, United States

Midwest Allergy Sinus Asthma, SC

🇺🇸

Normal, Illinois, United States

Dundee Dermatology

🇺🇸

West Dundee, Illinois, United States

NorthShore University HealthSystem Dermatology Clinical Trials Unit

🇺🇸

Skokie, Illinois, United States

Ds Research

🇺🇸

Clarksville, Indiana, United States

Dawes Fretzin Dermatology Group, LLC

🇺🇸

Indianapolis, Indiana, United States

Dawes Fretzin Clinical Research Group, LLC

🇺🇸

Indianapolis, Indiana, United States

The Indiana Clinical Trials Center

🇺🇸

Plainfield, Indiana, United States

Kansas City Dermatology, PA

🇺🇸

Overland Park, Kansas, United States

Owensboro Dermatology Associates

🇺🇸

Owensboro, Kentucky, United States

Meridian Clinical Research, LLC

🇺🇸

Baton Rouge, Louisiana, United States

DermAssociates, LLC

🇺🇸

Rockville, Maryland, United States

Chesapeake Clinical Research, Inc.

🇺🇸

White Marsh, Maryland, United States

Tufts Medical Center

🇺🇸

Boston, Massachusetts, United States

MetroBoston Clinical Partners, LLC

🇺🇸

Brighton, Massachusetts, United States

Massachusetts General Hospital - Clinical Unit for Research Trials in Skin (CURTIS)

🇺🇸

Boston, Massachusetts, United States

Onyx Clinical Research

🇺🇸

Flint, Michigan, United States

Somerset Skin Centre

🇺🇸

Troy, Michigan, United States

MediSearch Clinical Trials

🇺🇸

Saint Joseph, Missouri, United States

Saint Louis University Dermatology

🇺🇸

Saint Louis, Missouri, United States

Forest Hills Dermatology Group

🇺🇸

New York, New York, United States

UR Dermatology at College Town

🇺🇸

Rochester, New York, United States

Cary Dermatology Center, PA

🇺🇸

Cary, North Carolina, United States

PMG Research of Raleigh, LLC d/b/a PMG Research of Cary

🇺🇸

Cary, North Carolina, United States

Medication Management, LLC

🇺🇸

Greensboro, North Carolina, United States

Carolina Research Center, Inc.

🇺🇸

Shelby, North Carolina, United States

PMG Research of Wilmington, LLC

🇺🇸

Wilmington, North Carolina, United States

Lynn Health Science Institute

🇺🇸

Oklahoma City, Oklahoma, United States

The Ohio State University Dermatology East

🇺🇸

Gahanna, Ohio, United States

Paddington Testing Co, Inc.

🇺🇸

Philadelphia, Pennsylvania, United States

Synexus Clinical Research US, Inc.

🇺🇸

Anderson, South Carolina, United States

Tanenbaum Dermatology Center

🇺🇸

Memphis, Tennessee, United States

The University of Texas Health Science Center Houston

🇺🇸

Bellaire, Texas, United States

Menter Dermatology Research Institute

🇺🇸

Dallas, Texas, United States

Center for Clinical Studies, LTD.LLP

🇺🇸

Webster, Texas, United States

Austin Institute for Clinical Research, Inc.

🇺🇸

Pflugerville, Texas, United States

Ventavia Research Group

🇺🇸

Hurst, Texas, United States

Center for Clinical Studies, LTD. LLP

🇺🇸

Houston, Texas, United States

Virginia Clinical Research, Inc

🇺🇸

Norfolk, Virginia, United States

Virginia Dermatology and Skin Cancer Center

🇺🇸

Norfolk, Virginia, United States

Pace Dermatology Associates

🇺🇸

Tacoma, Washington, United States

Fort Norfolk Diagnostic Center

🇺🇸

Norfolk, Virginia, United States

Dermatology Specialists of Spokane

🇺🇸

Spokane, Washington, United States

Dermatology Associates of Seattle

🇺🇸

Seattle, Washington, United States

Principle Research Solutions

🇺🇸

Spokane, Washington, United States

MultiCare Allenmore Hospital

🇺🇸

Tacoma, Washington, United States

Multicare Institute for Research and Innovation

🇺🇸

Tacoma, Washington, United States

CONEXA Investigación Clínica S.A.

🇦🇷

Caba, Buenos Aires, Argentina

Framingham Centro Medico

🇦🇷

La Plata, Buenos Aires, Argentina

Hospital Universitario Austral

🇦🇷

Pilar, Buenos Aires, Argentina

Psoriahue Medicina Interdisciplinaria

🇦🇷

C.a.b.a., Argentina

The Royal Children's Hospital

🇦🇺

Parkville, Victoria, Australia

Royal Melbourne Hospital

🇦🇺

Parkville, VIC, Australia

Sinclair Dermatology

🇦🇺

East Melbourne, Victoria, Australia

University Hospital Brussels

🇧🇪

Brussels, Belgium

Cliniques Universitaires Saint-Luc

🇧🇪

Bruxelles, Belgium

Hospital de Clinicas de Porto Alegre (HCPA)

🇧🇷

Porto Alegre, RS, Brazil

Fundacao do ABC - Faculdade de Medicina do ABC

🇧🇷

Santo Andre, SP, Brazil

Tecnolab Medicina Diagnostica

🇧🇷

Santo Andre, SP, Brazil

Pesquisare Saude S/S Ltda

🇧🇷

Santo Andre, SP, Brazil

Tecnolab - Unidade Matriz

🇧🇷

Sao Bernardo do Campo, SP, Brazil

MHAT Dobrich AD

🇧🇬

Dobrich, Bulgaria

MC Asklepii" OOD

🇧🇬

Dupnitsa, Bulgaria

MHAT ''Dr. Tota Venkova'' AD

🇧🇬

Gabrovo, Bulgaria

"Acibadem City Clinic MHAT Tokuda" EAD

🇧🇬

Sofia, Bulgaria

"DCC Aleksandrovska" EOOD

🇧🇬

Sofia, Bulgaria

"DCC Fokus-5-Medical Establishment for OutpatientCare"EOOD

🇧🇬

Sofia, Bulgaria

Military Medical Academy MHAT Sofia

🇧🇬

Sofia, Bulgaria

"Mc Synexus Sofia" Eood

🇧🇬

Sofia, Bulgaria

Dermatology Clinic "Sofia" - group practice for specialized outpatient medical care

🇧🇬

Sofia, Bulgaria

"ACIBADEM City Clinic Medical Center Varna" EOOD

🇧🇬

Varna, Bulgaria

ACIBADEM City Clinic Diagnostic-Consultative Center EOOD

🇧🇬

Sofia, Bulgaria

Medical Center Synexus Sofia EOOD-branch Stara Zagora

🇧🇬

Stara Zagora, Bulgaria

"DCC Mladost-M Varna" OOD

🇧🇬

Varna, Bulgaria

Dermatology Research Institute

🇨🇦

Calgary, Alberta, Canada

Wiseman Dermatology Research Inc.

🇨🇦

Winnipeg, Manitoba, Canada

Pacific Dermaesthetics Inc.

🇨🇦

Vancouver, British Columbia, Canada

Winnipeg Clinic

🇨🇦

Winnipeg, Manitoba, Canada

CCA Medical Research

🇨🇦

Ajax, Ontario, Canada

Kingsway Clinical Research

🇨🇦

Etobicoke, Ontario, Canada

SimcoDerm Medical and Surgical Dermatology Center

🇨🇦

Barrie, Ontario, Canada

Derm Effects

🇨🇦

London, Ontario, Canada

DermEdge Research

🇨🇦

Mississauga, Ontario, Canada

North Bay Dermatology Centre

🇨🇦

North Bay, Ontario, Canada

Oshawa Clinic Dermatology Trials

🇨🇦

Oshawa, Ontario, Canada

Dermatology Ottawa Research Centre

🇨🇦

Ottawa, Ontario, Canada

SKiN Centre for Dermatology

🇨🇦

Peterborough, Ontario, Canada

The Centre for Dermatology

🇨🇦

Richmond Hill, Ontario, Canada

York Dermatology Clinic and Research Centre

🇨🇦

Richmond Hill, Ontario, Canada

North York Research Inc.

🇨🇦

Toronto, Ontario, Canada

Medicor Research Inc

🇨🇦

Sudbury, Ontario, Canada

Sudbury Skin Clinique

🇨🇦

Sudbury, Ontario, Canada

Clinique de Radiologie du Saguenay Enr.

🇨🇦

Chicoutimi, Quebec, Canada

XLR8 Medical Research Inc.

🇨🇦

Windsor, Ontario, Canada

Dr. Rachel Asiniwasis, Medical Professional Corp.

🇨🇦

Regina, Saskatchewan, Canada

Intermed groupe santé

🇨🇦

Chicoutimi, Quebec, Canada

Diex Research Sherbrooke Inc.

🇨🇦

Sherbrooke, Quebec, Canada

Centre de Recherche Dermatologique du Quebec metropolitain (CRDQ)

🇨🇦

Quebec, Canada

Centre de Recherche Saint-Louis

🇨🇦

Quebec, Canada

Clinica Dermacross S.A.

🇨🇱

Santiago, Region Metropolitana, Chile

Hospital Clinico Universidad de Chile

🇨🇱

Santiago, Región Metropolitana, Chile

The First Affiliated Hospital, Sun Yat-sen University

🇨🇳

Guangzhou, Guangdong, China

The second Xiangya Hospital,Central South University

🇨🇳

Changsha, Hunan, China

The First Affiliated Hospital With Nanjing University

🇨🇳

Nanjing, Jiangsu, China

Hangzhou Third Hospital

🇨🇳

Hangzhou, Zhejiang, China

Zhejiang Provincial People's Hospital/Dermatology Department

🇨🇳

Hangzhou, Zhejiang, China

The Second Affiliated Hospital of Army Medical University,PLA

🇨🇳

Chongqing, China

Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University

🇨🇳

Hangzhou, Zhejiang, China

Xin Hua Hospital Affiliated to Shanghai Jiaotong University School of Medicine/Dermatology

🇨🇳

Shanghai, China

Lekarna Pod Kankem

🇨🇿

Kunta Hora, Czechia

Lekarna U Stribrneho orla (Pharmacy)

🇨🇿

Nachod, Czechia

Lekarna Fakultni Nemocnice Ostrava

🇨🇿

Ostrava - Poruba, Czechia

Lekarna Rezidence Nova Karolina

🇨🇿

Ostrava, Czechia

BENU Lekarna

🇨🇿

Pardubice, Czechia

Lekarna, Nemocnice Pardubickeho kraje, a.s. , Pardubicka nemocnice

🇨🇿

Pardubice, Czechia

Licca Clinical Research Institute

🇩🇪

Augsburg, Germany

Fachklinik Bad Bentheim

🇩🇪

Bad Bentheim, Germany

SRH Wald-Klinikum Gera GmbH

🇩🇪

Gera, Germany

Klinische Forschung Hamburg GmbH

🇩🇪

Hamburg, Germany

Universitaetsklinikum Schleswig-Holstein, Campus Kiel

🇩🇪

Kiel, Germany

Praxis Dr. med. Beate Schwarz

🇩🇪

Langenau, Germany

SIBAmed Studienzentrum GmbH

🇩🇪

Leipzig, Germany

Velocity Clinical Research Germany GmbH

🇩🇪

Leipzig, Germany

Universitätsklinikum Marburg

🇩🇪

Marburg, Germany

Dermatologische Gemeinschaftspraxis Dres. Quist

🇩🇪

Mainz, Germany

Ludwig-Maximilians-University Munich

🇩🇪

Munich, Germany

Hautaerztliche Gemeinschaftspraxis Dres. Leitz und Kollegen

🇩🇪

Stuttgart, Germany

Clinexpert Kft.

🇭🇺

Budapest, Hungary

Bp. Főváros XIX. Kerület Önkormányzat Kispesti Eü. Intézete

🇭🇺

Budapest, Hungary

Borsod-Abaúj-Zemplén Megyei Központi Kórház és Gyermek Gasztroenterológia II. emelet

🇭🇺

Miskolc, Hungary

Medmare Bt

🇭🇺

Veszprem, Hungary

Soroka University Medical Center

🇮🇱

Beer Sheva, Israel

Rabin Medical Center

🇮🇱

Petah Tikva, Israel

Istituto Clinico Humanitas IRCSS - UOC di Dermatologia

🇮🇹

Milan, Italy

Hoshikuma Dermatology・Allergy Clinic

🇯🇵

Fukuoka, Japan

Kyungpook National University Hospital

🇰🇷

Daegu, Korea, Republic of

Severance Hospital, Yonsei Univ. Health System

🇰🇷

Seoul, Korea, Republic of

Riga 1st Hospital, Clinic of Dermatology and STD

🇱🇻

Riga, Latvia

Childrens Clinical University Hospital State SLLC

🇱🇻

Riga, Latvia

Centro de Dermatologia de Monterrey

🇲🇽

Monterrey, Nuevo LEON, Mexico

Centro Multidisciplinario para el Desarrollo Especializado de la Investigacion Clinica en Yucatan

🇲🇽

Merida, Yucatan, Mexico

Servicios Hospitalarios de Mexico S.A. de C.V. (Hospital Ángeles Chihuahua)

🇲🇽

Chihuahua,CHIHUAHUA, Mexico

Hospital de Jesus, I.A.P.

🇲🇽

Mexico City, Mexico

Trials in Medicine S.C.

🇲🇽

Mexico City, Mexico

NZOZ Specjalistyczny Osrodek Dermatologiczny DERMAL s.c.

🇵🇱

Bialystok, Poland

DERMAPOLIS Medical Dermatology Center dr n. med. Edyta Gębska

🇵🇱

Chorzow, Poland

Szpital Sw. Wojciecha

🇵🇱

Gdansk, Poland

Uniwersyteckie Centrum Kliniczne Klinika Dermatologii, Wenerologii i Alergologii

🇵🇱

Gdansk, Poland

Synexus Polska Sp. z o.o. Oddzial w Gdyni

🇵🇱

Gdynia, Poland

Dermamedica S.R.O.

🇨🇿

Nachod, Czechia

Kozni ambulance Kutna Hora, s.r.o

🇨🇿

Kutná Hora, Czechia

Lekarna U Spasitele

🇨🇿

Praha, Czechia

Lekarna na Hranicni (Pharmacy)

🇨🇿

Svitavy, Czechia

Osrodek badan klinicznych AppleTree Clinics

🇵🇱

Lodz, Poland

Synexus Polska Sp. z o.o. Oddzial w Poznaniu

🇵🇱

Poznan, Poland

Clinical Research Center Sp. z o.o. MEDIC-R Sp. k.

🇵🇱

Poznan, Poland

Twoja Przychodnia Szczecinskie Centrum Medyczne

🇵🇱

Szczecin, Poland

MICS Centrum Medyczne Warszawa

🇵🇱

Warszawa, Poland

Centrum Medyczne AMED

🇵🇱

Warszawa, Poland

Synexus Polska Sp. z o.o. Oddzial w Warszawie

🇵🇱

Warszawa, Poland

RCMed Oddzial Warszawa

🇵🇱

Warszawa, Poland

Klinika Ambroziak Sp. z o.o.

🇵🇱

Warszawa, Poland

Carpe Diem Centrum Medycyny Estetycznej

🇵🇱

Warszawa, Poland

Synexus Polska Sp. z o.o. Oddzial we Wroclawiu

🇵🇱

Wroclaw, Poland

Centrum Medyczne Oporow

🇵🇱

Wroclaw, Poland

SC Centrul Medical de Diagnostic si Tratament Ambulator Neomed SRL

🇷🇴

Brasov, JUD. Brasov, Romania

Clinic of FSBEI HE Kirov SMU MOH Russia

🇷🇺

Kirov, Russian Federation

SC Delta Health Care SRL

🇷🇴

Bucharest, Romania

Limited Liability Company "Medical Center "Rheuma-Med"

🇷🇺

Kemerovo, Russian Federation

FSBEI HE "St. Petersburg State Pediatric Medical University" MoH RF

🇷🇺

Saint-Petersburg, Russian Federation

Military Medical Academy

🇷🇸

Belgrade, Serbia

RSBIH "Smolensk Regional Clinical Hospital"

🇷🇺

Smolensk, Russian Federation

General Hospital Pancevo

🇷🇸

Pancevo, Serbia

Summit Clinical Research, s.r.o.

🇸🇰

Bratislava - Metska Cast Nove Mesto, Slovakia

SUMMIT CLINICAL RESEARCH, s.r.o., Ambulancia vnutorneho lekarstva

🇸🇰

Bratislava, Slovakia

SKINKLINIK s.r.o.

🇸🇰

Bratislava- Mestská Časť Nové Mesto, Slovakia

Narodny ustav detskych chorob

🇸🇰

Bratislava, Slovakia

BeneDerma s.r.o.

🇸🇰

Bratislava, Slovakia

Derma therapy spol. s.r.o, Dermatovenerologicka ambulancia

🇸🇰

Bratislava, Slovakia

Nemocnica Kosice-Saca, a.s., 1. sukromna nemocnica, Kozna ambulancia

🇸🇰

Kosice-Saca, Slovakia

Derma-beauty, s.r.o., Dermatovenerologicka ambulancia

🇸🇰

Nitra, Slovakia

SANARE spol.s.r.o.

🇸🇰

Svidnik, Slovakia

Hospital Universitari Germans Trias i Pujol

🇪🇸

Badalona, Barcelona, Spain

Hospital Sant Joan de Deu

🇪🇸

Esplugues de Llobregat, Barcelona, Spain

Hospital Universitario Fundacion Alcorcon

🇪🇸

Alcorcon, Madrid, Spain

Hospital de la Santa Creu i Sant Pau Servicio de Dermatologia

🇪🇸

Barcelona, Spain

Hospital General Universitario Gregorio Maranon

🇪🇸

Madrid, Spain

Hospital Universitario Puerta de Hierro de Majadahonda

🇪🇸

Majadahonda, Madrid, Spain

Hospital Clinic de Barcelona

🇪🇸

Barcelona, Spain

Hospital Universitario Reina Sofia

🇪🇸

Cordoba, Spain

Hospital General Universitario de Alicante

🇪🇸

Alicante, Spain

Hospital Universitario de La Princesa

🇪🇸

Madrid, Spain

Hospital Universitario 12 de octubre

🇪🇸

Madrid, Spain

Hospital Universitario La Paz

🇪🇸

Madrid, Spain

Hospital de Montecelo

🇪🇸

Pontevedra, Spain

Hospital Universitario y Politecnico La Fe

🇪🇸

Valencia, Spain

Hospital Universitario Virgen de la Macarena

🇪🇸

Sevilla, Spain

Taipei Medical University-Shuang Ho Hospital

🇨🇳

New Taipei City, Taiwan

Hospital Universitario Miguel Servet

🇪🇸

Zaragoza, Spain

Kaohsiung Medical University Chung-Ho Memorial Hospital

🇨🇳

Kaohsiung, Taiwan

Chang Gung Memorial Hospital Linkou Branch

🇨🇳

Taoyuan City, Taiwan

Medinova Research

🇬🇧

Wokingham, Berkshire, United Kingdom

MeDiNova West London Quality Research Sites

🇬🇧

Wokingham, Berkshire, United Kingdom

MeDiNova South London Quality Research Site

🇬🇧

Orpington, Kent, United Kingdom

Accellacare North London

🇬🇧

Northwood, Middlesex, United Kingdom

Barnsley Hospital NHS Foundation Trust

🇬🇧

Barnsley, South Yorkshire, United Kingdom

Sheffield Teaching Hospitals NHS Foundation Trust, Northern General Hospital

🇬🇧

Sheffield, South Yorkshire, United Kingdom

MAC Clinical Research

🇬🇧

Cannock, United Kingdom

Sheffield Children's NHS Foundation Trust

🇬🇧

Sheffield, South Yorkshire, United Kingdom

University Hospital Bristol NHS Foundation Trust

🇬🇧

Bristol, United Kingdom

Accellacare Warwickshire

🇬🇧

Coventry, United Kingdom

West Glasgow Ambulatory Care Hospital

🇬🇧

Glasgow, United Kingdom

Accellacare South London

🇬🇧

Orpington, United Kingdom

Guy's Hospital-Guy's and St Thomas NHS Foundation Trust

🇬🇧

London, United Kingdom

MAC Clinical Research Ltd

🇬🇧

Manchester, United Kingdom

Accellacare Yorkshire

🇬🇧

Shipley, United Kingdom

The Skin Centre

🇦🇺

Benowa, Queensland, Australia

Investigational Drug Service

🇺🇸

Rochester, New York, United States

St George Dermatology & Skin Cancer Centre

🇦🇺

Kogarah, New South Wales, Australia

Asthma and Allergy Associates, PC

🇺🇸

Colorado Springs, Colorado, United States

Clarkston Skin Research

🇺🇸

Clarkston, Michigan, United States

Henry Ford Medical Center - Farmington Road

🇺🇸

West Bloomfield, Michigan, United States

Miami Dermatology & Laser Research, LLC

🇺🇸

Miami, Florida, United States

Olympian Clinical Research

🇺🇸

Tampa, Florida, United States

ForCare Clinical Research

🇺🇸

Tampa, Florida, United States

Clinical Research Trials of Florida, Inc.

🇺🇸

Tampa, Florida, United States

Center for Clinical Studies

🇺🇸

Tampa, Florida, United States

University of South Florida; Asthma, Allergy and Immunology Clinical Research Unit

🇺🇸

Tampa, Florida, United States

Skin Specialists PC

🇺🇸

Omaha, Nebraska, United States

Children's Hospital of Wisconsin Investigational Drug Service

🇺🇸

Milwaukee, Wisconsin, United States

Children's Hospital of Wisconsin Translational Research Unit

🇺🇸

Milwaukee, Wisconsin, United States

Qualmedica Research, LLC.

🇺🇸

Owensboro, Kentucky, United States

Health Concepts

🇺🇸

Rapid City, South Dakota, United States

Centro de Especialidades Mollabao (Area Sanitaria de Pontevedra e O Salnes)

🇪🇸

Pontevedra, Spain

M3-Wake Research, Inc.

🇺🇸

Raleigh, North Carolina, United States

Beacon Dermatology

🇨🇦

Calgary, Alberta, Canada

CARE Clinic Ltd

🇨🇦

Red Deer, Alberta, Canada

Consorcio Hospital General Universitario de Valencia

🇪🇸

Valencia, Spain

The University of Alabama at Birmingham, Department of Dermatology

🇺🇸

Birmingham, Alabama, United States

Emmaus Research Center, Inc.

🇺🇸

Anaheim, California, United States

California Dermatology & Clinical Research Institute

🇺🇸

Encinitas, California, United States

Marvel Research, LLC

🇺🇸

Huntington Beach, California, United States

Tilda Research Inc.

🇺🇸

Irvine, California, United States

Keck School of Medicine of University of Southern California

🇺🇸

Los Angeles, California, United States

Allergy & Asthma Associates of Southern California dba Southern California Research

🇺🇸

Mission Viejo, California, United States

Dermatology Specialists, Inc.

🇺🇸

Oceanside, California, United States

Peninsula Headlands LLC

🇺🇸

Rolling Hills Estates, California, United States

MedDerm Associates

🇺🇸

San Diego, California, United States

San Luis Dermatology and Laser Clinic

🇺🇸

San Luis Obispo, California, United States

Colorado Springs Dermatology Clinic, PC

🇺🇸

Colorado Springs, Colorado, United States

Southern California Dermatology, Inc.

🇺🇸

Santa Ana, California, United States

South Miami Medical & Research Group, Inc.

🇺🇸

Miami, Florida, United States

Clinical Research Trials of Florida

🇺🇸

Tampa, Florida, United States

Dermatologic Surgery Specialists, PC

🇺🇸

Macon, Georgia, United States

Columbus Regional Research Institute

🇺🇸

Columbus, Georgia, United States

The South Bend Clinic Center for Research

🇺🇸

South Bend, Indiana, United States

Institute for Asthma and Allergy

🇺🇸

Chevy Chase, Maryland, United States

Avant Research Associates LLC

🇺🇸

Crowley, Louisiana, United States

Revival Research Institute, LLC

🇺🇸

Troy, Michigan, United States

Mayo Clinic

🇺🇸

Rochester, Minnesota, United States

Hamzavi Dermatology

🇺🇸

Fort Gratiot, Michigan, United States

Accellacare - Wilmington

🇺🇸

Wilmington, North Carolina, United States

Portland Clinical Research dba Columbia Asthma & Allergy Clinic

🇺🇸

Clackamas, Oregon, United States

Dermatologists of Greater Columbus

🇺🇸

Bexley, Ohio, United States

Velocity Clinical Research, Medford

🇺🇸

Medford, Oregon, United States

Vital Prospects Clinical Research Institute, P.C.

🇺🇸

Tulsa, Oklahoma, United States

Arlington Research Center, Inc.

🇺🇸

Arlington, Texas, United States

International Clinical Research - Tennessee LLC

🇺🇸

Murfreesboro, Tennessee, United States

Dermatology Clinical Research Center of San Antonio

🇺🇸

San Antonio, Texas, United States

Summit Clinical Research, LLC

🇺🇸

Franklin, Virginia, United States

CINME Centro de Investigaciones Metabolicas

🇦🇷

C.a.b.a, Argentina

Servicio de Investigacion de Patolog-ias Alergicas del Instituto ABC - Rosario

🇦🇷

Rosario, Santa FE, Argentina

The Skin Hospital

🇦🇺

Westmead, New South Wales, Australia

Veracity Clinical Research Pty Ltd

🇦🇺

Woolloongabba, Queensland, Australia

Australian Clinical Research Network

🇦🇺

Maroubra, New South Wales, Australia

North Eastern Health Specialists

🇦🇺

Campbelltown, South Australia, Australia

Royal North Shore Hospital

🇦🇺

Saint Leonards NSW, Australia

Skin Health Institute Inc.

🇦🇺

Carlton, Victoria, Australia

Emeritus Research

🇦🇺

Camberwell, Australia

Instituto de Dermatologia e Estética do Brasil LTDA

🇧🇷

Rio de Janeiro, RJ, Brazil

University Hospital Antwerp

🇧🇪

Edegem, Belgium

Associacao dos Funcionarios Públicos do Estado do Rio Grande do Sul - Hospital Ernesto Dornelles

🇧🇷

Porto Alegre, RS, Brazil

IBPClin Pesquisa Clinica

🇧🇷

Rio de Janeiro, Brazil

Dr. Chih-ho Hong Medical Inc

🇨🇦

Surrey, British Columbia, Canada

Centro Medico SkinMed Limitada

🇨🇱

Santiago, Region Metropolitana, Chile

Phylasis Clinicas Research S. de R.L. de C.V.

🇲🇽

Cuautitlan Izcalli, Mexico

Care Clinic Centrum Medyczne

🇵🇱

Katowice, Poland

Centrum Medyczne Angelius Provita

🇵🇱

Katowice, Poland

REUMATIKA - "Centrum Reumatologii" NZOZ 2

🇵🇱

Warszawa, Poland

University of Southern California

🇺🇸

Los Angeles, California, United States

Centro Internacional de Estudios Clinicos - CIEC

🇨🇱

Santiago, Region Metropolitana, Chile

Szegedi Tudomanyegyetem Szent-Györgyi Albert

🇭🇺

Szeged, Hungary

NZOZ "DERMED" Centrum Medyczne Sp. z o.o. - Oddzial w Lodzi

🇵🇱

Lodz, Poland

Woden Dermatology

🇦🇺

Phillip, Australian Capital Territory, Australia

SE AOK Bor, Nemikortani es Boronkologiai Klinika

🇭🇺

Budapest, Hungary

Mehiläinen Neo

🇫🇮

Turku, Finland

EMED Centrum Uslug Medycznych Ewa Smialek

🇵🇱

Rzeszow, Poland

EMC Instytut Medyczny S.A. Przychodnia przy ul. Lowieckiej

🇵🇱

Wroclaw, Poland

Plymouth Hospitals NHS Trust, Derriford Hospital

🇬🇧

Plymouth, Devon, United Kingdom

Hospital Universitario de Gran Canaria Dr. Negrin

🇪🇸

Las Palmas de Gran Canaria, LAS Palmas, Spain

National Taiwan University Hospital

🇨🇳

Taipei, Taiwan

Mackay Memorial Hospital

🇨🇳

Taipei, Taiwan

Takagi Dermatology

🇯🇵

Obihiro-shi, Hokkaido, Japan

Gabinety Lekarskie Rivermed

🇵🇱

Poznan, Poland

MTZ Clinical Research Powered by Pratia

🇵🇱

Warszawa, Poland

Cabinet Medical de Dermatovenerologie Prof. Dr. Orasan Remus Ioan

🇷🇴

Cluj-Napoca, Jud. Cluj, Romania

SBIH "Chelyabinsk Regional Clinical Dermatovenerology dispensary"

🇷🇺

Chelyabinsk, Russian Federation

LLC "Pierre Wolkenstein Clinic of Skin Diseases"

🇷🇺

Saint-Petersburg, Russian Federation

Vitiligo center

🇷🇺

Saint-Petersburg, Russian Federation

FSBEI HE I.P.Pavlov SPbSMU MOH Russia

🇷🇺

Saint-Petersburg, Russian Federation

National Cheng-Kung University Hospital

🇨🇳

Tainan, Taiwan

Eastern Health - Box Hill Hospital

🇦🇺

Box Hill, Victoria, Australia

FSBI "State Research Centre of Dermatovenereology and Cosmetology" MoH RF

🇷🇺

Moscow, Russian Federation

Centralny Szpital Kliniczny Ministerstwa Spraw Wewnetrznych i Administracji w Warszawie

🇵🇱

Warszawa, Poland

Wojskowy Instytut Medyczny, Klinika Dermatologiczna

🇵🇱

Warszawa, Poland

Kliniczny Oddzial Chorob Wewnetrznych, Dermatologii i Alergologii

🇵🇱

Zabrze, Poland

Taichung Veterans General Hospital

🇨🇳

Taichung, Taiwan

Karma Clinical Trials, Inc.

🇨🇦

St. John's, Newfoundland and Labrador, Canada

Lukasz Matusiak "4Health"

🇵🇱

Wroclaw, Poland

NRC Institute of Immunology FMBA of Russia

🇷🇺

Moscow, Russian Federation

UC Davis Health

🇺🇸

Sacramento, California, United States

AdventHealth Orlando

🇺🇸

Orlando, Florida, United States

AdventHealth Pediatric Dermatology Orlando

🇺🇸

Orlando, Florida, United States

Advent Health Orlando - Investigational Drug Services

🇺🇸

Orlando, Florida, United States

Skin Sciences, PLLC

🇺🇸

Louisville, Kentucky, United States

Outpatient Services Center - AdventHealth Orlando

🇺🇸

Orlando, Florida, United States

Pediatric Outpatient Procedures and Sedation

🇺🇸

Orlando, Florida, United States

Accel Research Sites - Nona Pediatric Center

🇺🇸

Orlando, Florida, United States

PMG Research of Winston-Salem, LLC

🇺🇸

Winston-Salem, North Carolina, United States

Winston-Salem Dermatology and Surgery Center, PLLC

🇺🇸

Winston-Salem, North Carolina, United States

Tulane University Health Sciences Center

🇺🇸

New Orleans, Louisiana, United States

MUSC SCTR Research Nexus Clinic and Laboratory

🇺🇸

Charleston, South Carolina, United States

Unidad de Atención Médica e Investigación en Salud

🇲🇽

Mérida, Yucatán, Mexico

Stratica Medical

🇨🇦

Edmonton, Alberta, Canada

Alberta Dermasurgery Centre

🇨🇦

Edmonton, Alberta, Canada

Skin Research Institute

🇺🇸

Coral Gables, Florida, United States

Royal free London NHS Foundation Trust

🇬🇧

London, Greater London, United Kingdom

Icahn School of Medicine at Mount Sinai

🇺🇸

New York, New York, United States

One Health Research Clinic Atlanta, LLC

🇺🇸

Johns Creek, Georgia, United States

Accellacare - Cary

🇺🇸

Cary, North Carolina, United States

PMG Research of Wilmington LLC

🇺🇸

Wilmington, North Carolina, United States

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