Prospective Cohort Study on Catheter Associated Asymptomatic Thrombosis in Intensive Care Unit
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 203
- 试验地点
- 1
- 主要终点
- Proportion of patients developing Catheter related thrombosis and Incidence of CRT in patients in ICU
研究概览
简要总结
This study aims to describe the incidence of catheter-related and non-catheter-related thrombosis in a population of adults in ICU and to assess its correlation with alteration of coagulation parameters.
详细描述
Central venous catheter (CVC) is now indispensable in the monitoring and care of patients in intensive care (ICU). Unfortunately, one of the complications of its positioning is catheter-related thrombosis (CRT) and its consequences. Despite the widespread use of CVC and the extensive literature describing its complications, areas of uncertainty regarding the onset, treatment and prevention of CRT persist, especially with regard to asymptomatic thrombosis.
This study aims to describe the incidence of catheter-related and non-catheter-related thrombosis in a population of adults in ICU and to assess its correlation with alteration of coagulation parameters.
The main objective of this study is to assess the proportion of patients developing CRT (proportion) and the incidence of CRT (rate expressed in catheter events/days) in patients in ICU.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients over the age of 18
- •admitted to intensive care who have for clinical reasons need to place a central venous catheter
- •signing of informed consent
排除标准
- •patients under 18 years of age
- •Known cancer status
- •Congenital thrombophilia
结局指标
主要结局
Proportion of patients developing Catheter related thrombosis and Incidence of CRT in patients in ICU
时间窗: Until CVC removal
The main objective of this study is to assess the proportion of patients developing CRT (proportion) and the incidence of CRT (rate expressed in catheter events/days) in patients in ICU.
次要结局
- the association of thrombosis with alterations of hemocoagulative parameters(Until CVC removal)
- describe the clinical measures that have been taken following the diagnosis of CRT.describe the clinical measures that have been taken following the diagnosis of CRT.(Until CVC removal)
- Deep venous thrombosis (DVT) proportion and Incidence(Until CVC removal)
- Proportion of various types of thrombotic apposition(Until CVC removal)
研究者
Mauro Panigada
Principal Investigator
Policlinico Hospital