Prospective Cohort Study on Catheter Associated Asymptomatic Thrombosis in Intensive Care Unit
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Central Venous Catheters
- Sponsor
- Policlinico Hospital
- Enrollment
- 203
- Locations
- 1
- Primary Endpoint
- Proportion of patients developing Catheter related thrombosis and Incidence of CRT in patients in ICU
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
This study aims to describe the incidence of catheter-related and non-catheter-related thrombosis in a population of adults in ICU and to assess its correlation with alteration of coagulation parameters.
Detailed Description
Central venous catheter (CVC) is now indispensable in the monitoring and care of patients in intensive care (ICU). Unfortunately, one of the complications of its positioning is catheter-related thrombosis (CRT) and its consequences. Despite the widespread use of CVC and the extensive literature describing its complications, areas of uncertainty regarding the onset, treatment and prevention of CRT persist, especially with regard to asymptomatic thrombosis. This study aims to describe the incidence of catheter-related and non-catheter-related thrombosis in a population of adults in ICU and to assess its correlation with alteration of coagulation parameters. The main objective of this study is to assess the proportion of patients developing CRT (proportion) and the incidence of CRT (rate expressed in catheter events/days) in patients in ICU.
Investigators
Mauro Panigada
Principal Investigator
Policlinico Hospital
Eligibility Criteria
Inclusion Criteria
- •patients over the age of 18
- •admitted to intensive care who have for clinical reasons need to place a central venous catheter
- •signing of informed consent
Exclusion Criteria
- •patients under 18 years of age
- •Known cancer status
- •Congenital thrombophilia
Outcomes
Primary Outcomes
Proportion of patients developing Catheter related thrombosis and Incidence of CRT in patients in ICU
Time Frame: Until CVC removal
The main objective of this study is to assess the proportion of patients developing CRT (proportion) and the incidence of CRT (rate expressed in catheter events/days) in patients in ICU.
Secondary Outcomes
- the association of thrombosis with alterations of hemocoagulative parameters(Until CVC removal)
- describe the clinical measures that have been taken following the diagnosis of CRT.describe the clinical measures that have been taken following the diagnosis of CRT.(Until CVC removal)
- Deep venous thrombosis (DVT) proportion and Incidence(Until CVC removal)
- Proportion of various types of thrombotic apposition(Until CVC removal)